Attempts to Understand Metastasis Formation III, Ursula G?nthert; Peter M. Schlag; Walter Birchmeie
Автор: Ursula G?nthert; Walter Birchmeier Название: Attempts to Understand Metastasis Formation II ISBN: 3642646980 ISBN-13(EAN): 9783642646980 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In metastasis, tumor cells disseminate from the primary lesion and home to secondary organs where they may remain dormant for a long time. Metastasis formation is still the most feared manifestation for tumor patients and clinicians. Although improvements have been made concerning earlier detection and specific therapy, most of the cancer patients still die ot distant metastases. The purpose of these three volumes is to review the recent progress in molecular metas- tasis research and to attempt to further understand the biol- ogy of this multifocal process. With respect to present day molecular biology, the pioneers of metastasis research established the basic concepts of metasta- sis formation in the 1970s and 1980s, namely, clonal selection of metastatic cells, heterogeneity of metastatic subpopulations, organ specificity of metastasis and the importance of angio- genesis (Fidler, Kripke, Nicolson, Folkman and others). In the 1980s and 1990s, several of the molecules involved were identified and their network interactions elucidated. These three volumes of Current Topics in Microbiology and Immuno- logy compile the most recent developments on these meta- stasis-related molecules; their interactions, regulation, and ways to interfere with their action. It became evident that metastasis-related molecules are confined to distinct cellular compartments, such as the extracellular space, the cell membrane, the cytoplasmic signalling network, and the nuclear regulatory system. For the complex tnetastatic cascade, proteolysis and alterations in adhesive functions are the most obvious and thus one of the most thoroughly investigated processes.
Автор: Beauchemin Название: Metastasis of Colorectal Cancer ISBN: 9048188326 ISBN-13(EAN): 9789048188321 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers colon cancer metastasis from fundamental aspects to clinical practice. Major topics include physiopathology, genetic and epigenetic controls, cancer initiating cells, epithelial-mesenchymal transition, growth factors and signalling, and more.
Автор: Chris Maxwell; Cal Roskelley Название: Genomic Instability and Cancer Metastasis ISBN: 3319352954 ISBN-13(EAN): 9783319352954 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Metastasis is the primary cause of mortality associated with cancer, and tumor genomic heterogeneity is a likely source for the cells that support cancer progression, resistance to therapy, and disease relapse.
Автор: Miriam Dwek; Udo Schumacher; Susan A. Brooks Название: Metastasis Research Protocols ISBN: 1493948873 ISBN-13(EAN): 9781493948871 Издательство: Springer Рейтинг: Цена: 14673.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This new edition offers updates and important new techniques for illuminating the processes underlying research on metastasis. Presents techniques applicable to living cells and tissues, to cell behavior in vitro, to animal models and mathematical constructs.
Автор: Robert B. Dickson; Marc E. Lippman Название: Mammary Tumor Cell Cycle, Differentiation, and Metastasis ISBN: 1461285364 ISBN-13(EAN): 9781461285366 Издательство: Springer Рейтинг: Цена: 72533.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Mammary Tumor Cell Cycle, Differentiation and Metastasis is the fifth volume since 1988 in a series designed to broadly examine current advances in the cellular and molecular biology of breast cancer.
Автор: Ursula G?nthert; Walter Birchmeier Название: Attempts to Understand Metastasis Formation I ISBN: 3642646972 ISBN-13(EAN): 9783642646973 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Miriam Dwek; Susan A. Brooks; Udo Schumacher Название: Metastasis Research Protocols ISBN: 1493956310 ISBN-13(EAN): 9781493956319 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Now in a second, revised edition, this practical companion to the methodologies of researching cancer growth includes topical introductions and stepwise, reproducible protocols for laboratory processes, as well as invaluable troubleshooting tips.
Автор: Volker Schirrmacher; Reinhard Schwartz-Albiez Название: Cancer Metastasis ISBN: 3540504710 ISBN-13(EAN): 9783540504719 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the 2nd Int. Conference of the Metastasis Research Society of a Satellite Workshop, Heidelberg, September 26-29, 1988
Автор: Gaspar Banfalvi Название: Homeostasis - Tumor - Metastasis ISBN: 9402402489 ISBN-13(EAN): 9789402402483 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book explains how lifestyle, environment, genetic makeup and social conditions can help maintain or upset the biological balance and lead to cancer. Cover tumor formation as well as mestasis, the spread of tumor cells to distant parts of the organism.
Автор: Julia V. Burnier; Miguel N Burnier Название: Experimental and Clinical Metastasis ISBN: 148999663X ISBN-13(EAN): 9781489996633 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book discusses basic and clinical aspects as well as translational aspects of metastatic research. It includes the latest developments in the field and provides a clear and extensive review of experimental implications of metastatic disease.
Автор: Marie-Odile Parat Название: Morphine and Metastasis ISBN: 9400792964 ISBN-13(EAN): 9789400792968 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book explores the effect of morphine and other opioids on tumor growth and metastasis. Discusses which type of post surgical pain management can minimize the risk of recurrence or metastasis, animal research on the effects of morphine on tumors and more.
Описание: Convertases are widely expressed activating enzymes involved in various physiological and pathological processes. The purpose of this book is to provide detailed and updated information on the role of these molecules in cancer. This book is the first to summarize current knowledge about the importance of protein precursors maturation by the convertases in tumor progression, angiogenesis and metastasis. In each chapter, the importance of the convertases in the activation of various cancer-related molecules including growth factors, adhesion molecules and proteases is discussed. Also this book covers the role of some convertases in the clinical setting. The book will be of interest to basic researchers as well as clinicians. It will also interest those working in the cancer research area and the pharmaceutical industry, who are looking for new strategies in cancer therapy. Finally, this book is also a useful reference for researchers and clinicians pursuing research on growth factors, adhesion molecules, proteases and their implications in the processes of tumor progression, angiogenesis and metastasis.
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