Автор: Banfalvi Gaspar Название: Homeostasis - Tumor - Metastasis ISBN: 940077334X ISBN-13(EAN): 9789400773349 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book explains how lifestyle, environment, genetic makeup and social conditions can help maintain or upset the biological balance and lead to cancer. Cover tumor formation as well as mestasis, the spread of tumor cells to distant parts of the organism.
Автор: Beauchemin Название: Metastasis of Colorectal Cancer ISBN: 9048188326 ISBN-13(EAN): 9789048188321 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers colon cancer metastasis from fundamental aspects to clinical practice. Major topics include physiopathology, genetic and epigenetic controls, cancer initiating cells, epithelial-mesenchymal transition, growth factors and signalling, and more.
Автор: Nektarios Tavernarakis Название: Protein Metabolism and Homeostasis in Aging ISBN: 1489979395 ISBN-13(EAN): 9781489979391 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book examines the role of protein metabolism and homeostasis in aging. It offers an overview of the current knowledge in the area, including protein synthesis, accuracy and repair, post-translational modifications, and degradation and turnover.
Автор: Jen-Tsan Ashley Chi Название: Molecular Genetics of Dysregulated pH Homeostasis ISBN: 1493916823 ISBN-13(EAN): 9781493916825 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Most biological reactions and functions occur within a narrow range of pH. Any changes in the pH have great impacts on the biological functional at every level, including protein folding, enzymatic activities and proliferation and cell death. Therefore, maintain the pH homeostasis at the local or systemic level is one of the highest priorities for all multicellular organisms. Many redundant mechanisms are in place to maintain the pH homeostasis, a topic that is well covered in the scientific literature and medical textbooks. However, when the pH homeostasis is disrupted in various physiological adaptations and pathological situations, resulting acidity may trigger significant pathophysiological events and modulate disease outcomes. Therefore, understanding how various cells sense and react to acidity have broad impact in a wide variety of human diseases, including cancer, stroke, myocardial infarction and diabetes, renal and infectious diseases. In this book, many investigators have summarized the molecular genetics on the detailed mechanisms by which different mammalian cells sense and response acidity. These chapters cover the acidity with broad impact in biological understanding and human diseases and review various sensing mechanism and cellular responses to pH alterations in both physiological (taste, pain) and pathological settings (ischemia and cancers). Furthermore, these authors present a broad spectrum of investigative approaches to cellular response to acidosis in a in wide variety of human diseases.
Автор: E. Carafoli; J. Krebs Название: Calcium Homeostasis ISBN: 3642635326 ISBN-13(EAN): 9783642635328 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Автор: Ingrid C. Gelissen; Andrew J. Brown Название: Cholesterol Homeostasis ISBN: 1493968734 ISBN-13(EAN): 9781493968732 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides state-of-the-art techniques for studying various aspects of cholesterol homeostasis, including its uptake, synthesis and efflux from the cell, as well as its trafficking within the cell.
Автор: Susanne Sattler; Teresa Kennedy-Lydon Название: The Immunology of Cardiovascular Homeostasis and Pathology ISBN: 3319576119 ISBN-13(EAN): 9783319576114 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Preface Introduction Section 1: The Immune system in tissue and organ homeostasis Chapter 1: The Immune system beyond the fight against infection Section 2: Immune functions and properties of resident cells in the heart and cardiovascular system Chapter 2: Cardiomyocytes: Paying for the Tolls - The High Cost of the Innate Immune System for the Cardiac Myocyte Chapter 3: Fibroblasts: Properties and immune function of cardiac fibroblasts Chapter 4: Endothelial cells Chapter 5: Pericytes Chapter 6: Tissue-resident macrophages: The role of cardiac tissue macrophages in homeostasis and disease Section 3: The immune system in cardiovascular pathology Chapter 7: Atherosclerosis Chapter 8: Immune mediated heart disease Chapter 9: Vasculitis in the central nervous system Chapter 10: Cardiac Autoimmunity: Myocarditis Section 4: The immune system in repair and regeneration after myocardial infarct Chapter 11: Lymphocytes at the heart of wound healing Chapter 12: The innate immune system in cardiovascular repair and regeneration
Автор: Joan Stein-Streilein Название: Infection, Immune Homeostasis and Immune Privilege ISBN: 303480797X ISBN-13(EAN): 9783034807975 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Organs and tissues that can tolerate little or no inflammation have developed multiple overlapping mechanisms of immune protection in the absence of inflammation. These areas have been designated “immune-privileged sites” by Peter Medawar and include the central nervous system, eye, reproductive tract, testis and possibly the liver. Mechanisms of immune homeostasis found in less immune-regulated organs are often evident in the immune privileged sites and vice versa. It is important that the non-inflammatory mechanisms that contribute to immune privilege allow host defense against infectious organisms. This volume highlights the mechanisms leading to immune privilege in tissues and organs, the deviation of immune responses and the modification of the behavior of the immune cells that manage to cross the blood barriers of tissues, in the context of infection.
Автор: Richard Bucala; J?rgen Bernhagen Название: MIF Family Cytokines in Innate Immunity and Homeostasis ISBN: 331952352X ISBN-13(EAN): 9783319523521 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The role of the cytokine macrophage migration inhibitory factor (MIF) in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well-established.
Автор: Jen-Tsan Ashley Chi Название: Molecular Genetics of Dysregulated pH Homeostasis ISBN: 1493953176 ISBN-13(EAN): 9781493953172 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Most biological reactions and functions occur within a narrow range of pH. Any changes in the pH have great impacts on the biological functional at every level, including protein folding, enzymatic activities and proliferation and cell death. Therefore, maintain the pH homeostasis at the local or systemic level is one of the highest priorities for all multicellular organisms. Many redundant mechanisms are in place to maintain the pH homeostasis, a topic that is well covered in the scientific literature and medical textbooks. However, when the pH homeostasis is disrupted in various physiological adaptations and pathological situations, resulting acidity may trigger significant pathophysiological events and modulate disease outcomes. Therefore, understanding how various cells sense and react to acidity have broad impact in a wide variety of human diseases, including cancer, stroke, myocardial infarction and diabetes, renal and infectious diseases. In this book, many investigators have summarized the molecular genetics on the detailed mechanisms by which different mammalian cells sense and response acidity. These chapters cover the acidity with broad impact in biological understanding and human diseases and review various sensing mechanism and cellular responses to pH alterations in both physiological (taste, pain) and pathological settings (ischemia and cancers). Furthermore, these authors present a broad spectrum of investigative approaches to cellular response to acidosis in a in wide variety of human diseases.
Автор: Alfred Locker Название: Biogenesis Evolution Homeostasis ISBN: 3540061347 ISBN-13(EAN): 9783540061342 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In 1963, 1965 and 1967 "Symposia on Quantitative Biology of Metabolism" were organized on the pretty island of Helgoland (Biologische Anstalt) by me in col- laboration with O.
Описание: Moreover, because a distinct set of biological events is involved in this death, these events themselves become reason- able targets for new pharmacological agents in the treatment of cancer. Michael Dexter June 1994 Martin Raff Andrew Wyllie x 1 Death from inside out: an overVIew ANDREW H.
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