MIF Family Cytokines in Innate Immunity and Homeostasis, Richard Bucala; J?rgen Bernhagen

Автор: Banfalvi Gaspar
Название: Homeostasis - Tumor - Metastasis
ISBN: 940077334X ISBN-13(EAN): 9789400773349
Издательство: Springer
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Цена: 23508.00 р.
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Описание: This book explains how lifestyle, environment, genetic makeup and social conditions can help maintain or upset the biological balance and lead to cancer. Cover tumor formation as well as mestasis, the spread of tumor cells to distant parts of the organism.

Автор: Jen-Tsan Ashley Chi
Название: Molecular Genetics of Dysregulated pH Homeostasis
ISBN: 1493916823 ISBN-13(EAN): 9781493916825
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Most biological reactions and functions occur within a narrow range of pH. Any changes in the pH have great impacts on the biological functional at every level, including protein folding, enzymatic activities and proliferation and cell death. Therefore, maintain the pH homeostasis at the local or systemic level is one of the highest priorities for all multicellular organisms. Many redundant mechanisms are in place to maintain the pH homeostasis, a topic that is well covered in the scientific literature and medical textbooks. However, when the pH homeostasis is disrupted in various physiological adaptations and pathological situations, resulting acidity may trigger significant pathophysiological events and modulate disease outcomes. Therefore, understanding how various cells sense and react to acidity have broad impact in a wide variety of human diseases, including cancer, stroke, myocardial infarction and diabetes, renal and infectious diseases. In this book, many investigators have summarized the molecular genetics on the detailed mechanisms by which different mammalian cells sense and response acidity. These chapters cover the acidity with broad impact in biological understanding and human diseases and review various sensing mechanism and cellular responses to pH alterations in both physiological (taste, pain) and pathological settings (ischemia and cancers). Furthermore, these authors present a broad spectrum of investigative approaches to cellular response to acidosis in a in wide variety of human diseases.

Автор: Ingrid C. Gelissen; Andrew J. Brown
Название: Cholesterol Homeostasis
ISBN: 1493968734 ISBN-13(EAN): 9781493968732
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This volume provides state-of-the-art techniques for studying various aspects of cholesterol homeostasis, including its uptake, synthesis and efflux from the cell, as well as its trafficking within the cell.

Автор: Susanne Sattler; Teresa Kennedy-Lydon
Название: The Immunology of Cardiovascular Homeostasis and Pathology
ISBN: 3319576119 ISBN-13(EAN): 9783319576114
Издательство: Springer
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Цена: 22359.00 р.
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Описание: Preface
Introduction
Section 1: The Immune system in tissue and organ homeostasis
Chapter 1: The Immune system beyond the fight against infection
Section 2: Immune functions and properties of resident cells in the heart and cardiovascular system
Chapter 2: Cardiomyocytes: Paying for the Tolls - The High Cost of the Innate Immune System for the Cardiac Myocyte
Chapter 3: Fibroblasts: Properties and immune function of cardiac fibroblasts
Chapter 4: Endothelial cells
Chapter 5: Pericytes
Chapter 6: Tissue-resident macrophages: The role of cardiac tissue macrophages in homeostasis and disease
Section 3: The immune system in cardiovascular pathology
Chapter 7: Atherosclerosis
Chapter 8: Immune mediated heart disease
Chapter 9: Vasculitis in the central nervous system
Chapter 10: Cardiac Autoimmunity: Myocarditis
Section 4: The immune system in repair and regeneration after myocardial infarct
Chapter 11: Lymphocytes at the heart of wound healing
Chapter 12: The innate immune system in cardiovascular repair and regeneration
​

Автор: Yuzuru Ishimura; Hideo Shimada; Makoto Suematsu
Название: Oxygen Homeostasis and Its Dynamics
ISBN: 4431684786 ISBN-13(EAN): 9784431684787
Издательство: Springer
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Цена: 12157.00 р.
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Описание: This first volume in a projected series contains the proceedings of the first of the Keio University International Symposia for Life Sciences and Medicine under the sponsorship of the Keio University Medical Science Fund.

Автор: Joan Stein-Streilein
Название: Infection, Immune Homeostasis and Immune Privilege
ISBN: 303480797X ISBN-13(EAN): 9783034807975
Издательство: Springer
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Цена: 23757.00 р.
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Описание: Organs and tissues that can tolerate little or no inflammation have developed multiple overlapping mechanisms of immune protection in the absence of inflammation. These areas have been designated “immune-privileged sites” by Peter Medawar and include the central nervous system, eye, reproductive tract, testis and possibly the liver. Mechanisms of immune homeostasis found in less immune-regulated organs are often evident in the immune privileged sites and vice versa. It is important that the non-inflammatory mechanisms that contribute to immune privilege allow host defense against infectious organisms. This volume highlights the mechanisms leading to immune privilege in tissues and organs, the deviation of immune responses and the modification of the behavior of the immune cells that manage to cross the blood barriers of tissues, in the context of infection.

Автор: Gaspar Banfalvi
Название: Homeostasis - Tumor - Metastasis
ISBN: 9402402489 ISBN-13(EAN): 9789402402483
Издательство: Springer
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Цена: 19589.00 р.
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Описание: This book explains how lifestyle, environment, genetic makeup and social conditions can help maintain or upset the biological balance and lead to cancer. Cover tumor formation as well as mestasis, the spread of tumor cells to distant parts of the organism.

Автор: Andrew L. Snow; Michael J. Lenardo
Название: Immune Homeostasis
ISBN: 1493959689 ISBN-13(EAN): 9781493959686
Издательство: Springer
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Цена: 16769.00 р.
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Описание: This book examines experimental techniques for measuring and analyzing immune cell dynamics, with an emphasizes lymphocyte programmed cell deaths in different contexts. It features expert tips and key implementation advice to guarantee successful results.

Автор: Jen-Tsan Ashley Chi
Название: Molecular Genetics of Dysregulated pH Homeostasis
ISBN: 1493953176 ISBN-13(EAN): 9781493953172
Издательство: Springer
Рейтинг:
Цена: 13974.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Most biological reactions and functions occur within a narrow range of pH. Any changes in the pH have great impacts on the biological functional at every level, including protein folding, enzymatic activities and proliferation and cell death. Therefore, maintain the pH homeostasis at the local or systemic level is one of the highest priorities for all multicellular organisms. Many redundant mechanisms are in place to maintain the pH homeostasis, a topic that is well covered in the scientific literature and medical textbooks. However, when the pH homeostasis is disrupted in various physiological adaptations and pathological situations, resulting acidity may trigger significant pathophysiological events and modulate disease outcomes. Therefore, understanding how various cells sense and react to acidity have broad impact in a wide variety of human diseases, including cancer, stroke, myocardial infarction and diabetes, renal and infectious diseases. In this book, many investigators have summarized the molecular genetics on the detailed mechanisms by which different mammalian cells sense and response acidity. These chapters cover the acidity with broad impact in biological understanding and human diseases and review various sensing mechanism and cellular responses to pH alterations in both physiological (taste, pain) and pathological settings (ischemia and cancers). Furthermore, these authors present a broad spectrum of investigative approaches to cellular response to acidosis in a in wide variety of human diseases.

Автор: Andrew L. Snow; Michael J. Lenardo
Название: Immune Homeostasis
ISBN: 1627032894 ISBN-13(EAN): 9781627032896
Издательство: Springer
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Цена: 15372.00 р.
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Описание: This book examines experimental techniques for measuring and analyzing immune cell dynamics, with an emphasizes lymphocyte programmed cell deaths in different contexts. It features expert tips and key implementation advice to guarantee successful results.

Автор: Alain Beschin; Werner E. G. M?ller
Название: Invertebrate Cytokines and the Phylogeny of Immunity
ISBN: 3642622364 ISBN-13(EAN): 9783642622366
Издательство: Springer
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Цена: 16769.00 р.
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Описание: Based on the assumption that invertebrates as well as vertebrates possess factors regulating hematopoiesis, response to infection or wounding, studies dealing with the evolution of immunity have focused on the isolation and characterization of putative cytokine-related molecules from invertebrates.