Infection, Immune Homeostasis and Immune Privilege, Joan Stein-Streilein
Автор: Jen-Tsan Ashley Chi Название: Molecular Genetics of Dysregulated pH Homeostasis ISBN: 1493916823 ISBN-13(EAN): 9781493916825 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Most biological reactions and functions occur within a narrow range of pH. Any changes in the pH have great impacts on the biological functional at every level, including protein folding, enzymatic activities and proliferation and cell death. Therefore, maintain the pH homeostasis at the local or systemic level is one of the highest priorities for all multicellular organisms. Many redundant mechanisms are in place to maintain the pH homeostasis, a topic that is well covered in the scientific literature and medical textbooks. However, when the pH homeostasis is disrupted in various physiological adaptations and pathological situations, resulting acidity may trigger significant pathophysiological events and modulate disease outcomes. Therefore, understanding how various cells sense and react to acidity have broad impact in a wide variety of human diseases, including cancer, stroke, myocardial infarction and diabetes, renal and infectious diseases. In this book, many investigators have summarized the molecular genetics on the detailed mechanisms by which different mammalian cells sense and response acidity. These chapters cover the acidity with broad impact in biological understanding and human diseases and review various sensing mechanism and cellular responses to pH alterations in both physiological (taste, pain) and pathological settings (ischemia and cancers). Furthermore, these authors present a broad spectrum of investigative approaches to cellular response to acidosis in a in wide variety of human diseases.
Автор: E. Carafoli; J. Krebs Название: Calcium Homeostasis ISBN: 3642635326 ISBN-13(EAN): 9783642635328 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Автор: Andrew L. Snow; Michael J. Lenardo Название: Immune Homeostasis ISBN: 1627032894 ISBN-13(EAN): 9781627032896 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book examines experimental techniques for measuring and analyzing immune cell dynamics, with an emphasizes lymphocyte programmed cell deaths in different contexts. It features expert tips and key implementation advice to guarantee successful results.
Автор: Andrew L. Snow; Michael J. Lenardo Название: Immune Homeostasis ISBN: 1493959689 ISBN-13(EAN): 9781493959686 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book examines experimental techniques for measuring and analyzing immune cell dynamics, with an emphasizes lymphocyte programmed cell deaths in different contexts. It features expert tips and key implementation advice to guarantee successful results.
Автор: D.H. Wang Название: Molecular Sensors for Cardiovascular Homeostasis ISBN: 1489991999 ISBN-13(EAN): 9781489991997 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Biological homeostasis is maintained via intact function of an array of molecules detecting changes of microenvironments inside and outside of the biological system. These molecules, including cell membrane proteins and ion channels, are intimately involved in a variety of sensory pathways and respond to environmental stimuli, including altered temperature, pH, mechanical and osmotic stress, intra- and extracellular messengers, as well as changes in energy consumption. The book reveals the state-of-the-science of several newly discovered ion channel families and their role in the pathogenesis of cardiovascular diseases. This work offers comprehensive and up-to-date information for a deeper understanding of the relationship between macro- and micro-environments, ion channels, and pathophysiological responses, and for developing novel therapies for treating devastating cardiovascular illnesses.
Автор: Alfred Locker Название: Biogenesis Evolution Homeostasis ISBN: 3540061347 ISBN-13(EAN): 9783540061342 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In 1963, 1965 and 1967 "Symposia on Quantitative Biology of Metabolism" were organized on the pretty island of Helgoland (Biologische Anstalt) by me in col- laboration with O.
Автор: Nektarios Tavernarakis Название: Protein Metabolism and Homeostasis in Aging ISBN: 1489979395 ISBN-13(EAN): 9781489979391 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book examines the role of protein metabolism and homeostasis in aging. It offers an overview of the current knowledge in the area, including protein synthesis, accuracy and repair, post-translational modifications, and degradation and turnover.
Автор: Gaspar Banfalvi Название: Homeostasis - Tumor - Metastasis ISBN: 9402402489 ISBN-13(EAN): 9789402402483 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book explains how lifestyle, environment, genetic makeup and social conditions can help maintain or upset the biological balance and lead to cancer. Cover tumor formation as well as mestasis, the spread of tumor cells to distant parts of the organism.
Автор: Susanne Sattler; Teresa Kennedy-Lydon Название: The Immunology of Cardiovascular Homeostasis and Pathology ISBN: 3319576119 ISBN-13(EAN): 9783319576114 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Preface Introduction Section 1: The Immune system in tissue and organ homeostasis Chapter 1: The Immune system beyond the fight against infection Section 2: Immune functions and properties of resident cells in the heart and cardiovascular system Chapter 2: Cardiomyocytes: Paying for the Tolls - The High Cost of the Innate Immune System for the Cardiac Myocyte Chapter 3: Fibroblasts: Properties and immune function of cardiac fibroblasts Chapter 4: Endothelial cells Chapter 5: Pericytes Chapter 6: Tissue-resident macrophages: The role of cardiac tissue macrophages in homeostasis and disease Section 3: The immune system in cardiovascular pathology Chapter 7: Atherosclerosis Chapter 8: Immune mediated heart disease Chapter 9: Vasculitis in the central nervous system Chapter 10: Cardiac Autoimmunity: Myocarditis Section 4: The immune system in repair and regeneration after myocardial infarct Chapter 11: Lymphocytes at the heart of wound healing Chapter 12: The innate immune system in cardiovascular repair and regeneration
Автор: Jen-Tsan Ashley Chi Название: Molecular Genetics of Dysregulated pH Homeostasis ISBN: 1493953176 ISBN-13(EAN): 9781493953172 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Most biological reactions and functions occur within a narrow range of pH. Any changes in the pH have great impacts on the biological functional at every level, including protein folding, enzymatic activities and proliferation and cell death. Therefore, maintain the pH homeostasis at the local or systemic level is one of the highest priorities for all multicellular organisms. Many redundant mechanisms are in place to maintain the pH homeostasis, a topic that is well covered in the scientific literature and medical textbooks. However, when the pH homeostasis is disrupted in various physiological adaptations and pathological situations, resulting acidity may trigger significant pathophysiological events and modulate disease outcomes. Therefore, understanding how various cells sense and react to acidity have broad impact in a wide variety of human diseases, including cancer, stroke, myocardial infarction and diabetes, renal and infectious diseases. In this book, many investigators have summarized the molecular genetics on the detailed mechanisms by which different mammalian cells sense and response acidity. These chapters cover the acidity with broad impact in biological understanding and human diseases and review various sensing mechanism and cellular responses to pH alterations in both physiological (taste, pain) and pathological settings (ischemia and cancers). Furthermore, these authors present a broad spectrum of investigative approaches to cellular response to acidosis in a in wide variety of human diseases.
Автор: Banfalvi Gaspar Название: Homeostasis - Tumor - Metastasis ISBN: 940077334X ISBN-13(EAN): 9789400773349 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book explains how lifestyle, environment, genetic makeup and social conditions can help maintain or upset the biological balance and lead to cancer. Cover tumor formation as well as mestasis, the spread of tumor cells to distant parts of the organism.
Автор: Richard Bucala; J?rgen Bernhagen Название: MIF Family Cytokines in Innate Immunity and Homeostasis ISBN: 331952352X ISBN-13(EAN): 9783319523521 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The role of the cytokine macrophage migration inhibitory factor (MIF) in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well-established.
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