Predictive Drug Testing on Human Tumor Cells, V. Hofmann; M.E. Berens; G. Martz
Автор: Pal, Ranadip Название: Predictive Modeling of Drug Sensitivity ISBN: 0128052740 ISBN-13(EAN): 9780128052747 Издательство: Elsevier Science Рейтинг: Цена: 12801.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Predictive Modeling of Drug Sensitivity gives an overview of drug sensitivity modeling for personalized medicine that includes data characterizations, modeling techniques, applications, and research challenges. It covers the major mathematical techniques used for modeling drug sensitivity, and includes the requisite biological knowledge to guide a user to apply the mathematical tools in different biological scenarios.
This book is an ideal reference for computer scientists, engineers, computational biologists, and mathematicians who want to understand and apply multiple approaches and methods to drug sensitivity modeling. The reader will learn a broad range of mathematical and computational techniques applied to the modeling of drug sensitivity, biological concepts, and measurement techniques crucial to drug sensitivity modeling, how to design a combination of drugs under different constraints, and the applications of drug sensitivity prediction methodologies.
Автор: Xu Название: Predictive Toxicology in Drug Safety ISBN: 0521763649 ISBN-13(EAN): 9780521763646 Издательство: Cambridge Academ Рейтинг: Цена: 19800.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is a handbook on drug discovery toxicology for scientists working in this field dedicated to the development of safe drugs. It provides information on the present knowledge of drug side effects and their mitigation strategy during drug discovery, gives guidance for risk assessment and promotes evidence-based toxicology.
Описание: By guiding in the application of techniques and tools for predicting ADMET outcomes in drug candidates, Predictive ADMET offers a road map for drug discovery scientists to generate effective and safe drugs for unmet medical needs.
Автор: A.N. Worden; D.V. Parke; J. Marks Название: The Future of Predictive Safety Evaluation ISBN: 9401079366 ISBN-13(EAN): 9789401079365 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Reproduction and fetal development in humans and experimental animals may be adversely affected by a wide range of drugs and environmental agents.
Автор: D.V. Parke; A.N. Worden; J. Marks Название: The Future of Predictive Safety Evaluation ISBN: 9401083363 ISBN-13(EAN): 9789401083362 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The earliest writings speak of such toxicity and, from the times of ancient Egypt and in the Old Tes- tament, controls have existed[l]. The Royal College of Physicians, for example, was originally established to control the activities of physicians within London.
Описание: An IT System for Personalized Medicine (ITS-PM) for HCC will provide the means to identify and determine the relative value of the wide number of variables, including clinical assessment of the patient -- functional status, liver function, degree of cirrhosis, and comorbidities;
Автор: Gary P. Moss; Darren R. Gullick; Simon C. Wilkinso Название: Predictive Methods in Percutaneous Absorption ISBN: 3662508311 ISBN-13(EAN): 9783662508312 Издательство: Springer Рейтинг: Цена: 16977.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book sheds new light on the development and use of quantitative models to describe the process of skin permeation.
Автор: Gary P. Moss; Darren R. Gullick; Simon C. Wilkinso Название: Predictive Methods in Percutaneous Absorption ISBN: 3662473704 ISBN-13(EAN): 9783662473702 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book sheds new light on the development and use of quantitative models to describe the process of skin permeation. It critically reviews the development of quantitative predictive models of skin absorption and discusses key recommendations for model development. Topics presented include an introduction to skin physiology; the underlying theories of skin absorption; the physical laboratory-based processes used to generate skin absorption data, which is in turn used to construct mathematical models describing the skin permeation process; algorithms of skin permeability including quantitative structure-activity (or permeability) relationships (QSARs or QSPRs); relationships between permeability and molecular properties; the development of formulation-focused approaches to models of skin permeability prediction; the use of artificial membranes, e.g. polydimethylsiloxane as alternatives to mammalian skin; and lastly, the use of novel Machine Learning methods in developing the next generation of predictive skin permeability models. The book will be of interest to all researchers in academia and industry working in pharmaceutical discovery and development, as well as readers from the field of occupational exposure and risk assessment, especially those whose work involves agrochemicals, bulk chemicals and cosmetics.
Автор: Godfrey Grech; Iris Grossman Название: Preventive and Predictive Genetics: Towards Personalised Medicine ISBN: 3319153439 ISBN-13(EAN): 9783319153438 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Pharmacogenomics supports personalized medicine by translating genome-based knowledge into clinical practice, offering enhanced benefit for patients and health-care systems at large. Current routine practice for diagnosing and treating patients is conducted by correlating parameters such as age, gender and weight with risks and expected treatment outcomes. In the new era of personalized medicine the healthcare provider is equipped with improved ability to prevent, diagnose, treat and predict outcomes on the basis of complex information sources, including genetic and genomic data. Targeted therapy and reliable prediction of expected outcomes offer patients access to better healthcare management, by way of identifying the therapies effective for the relevant patient group, avoiding prescription of unnecessary treatment and reducing the likelihood of developing adverse drug reactions.
Автор: Levenback Название: Prognostic & Predictive Factors Gynecologic Cancers ISBN: 0415391725 ISBN-13(EAN): 9780415391726 Издательство: Taylor&Francis Рейтинг: Цена: 30624.00 р. Наличие на складе: Поставка под заказ.
Описание: Gynecologic oncology takes a fresh look at a critical aspect of cancer treatment planning
Автор: Walker Название: Prognostic and Predictive Factors in Breast Cancer 2E ISBN: 0415422256 ISBN-13(EAN): 9780415422253 Издательство: Taylor&Francis Рейтинг: Цена: 26796.00 р. Наличие на складе: Поставка под заказ.
Описание: The first edition of this groundbreaking text established itself as the definitive reference on a topic of extreme interest and relevance to those involved in breast cancer management.This new Second Edition is filled with over 250 full-color images, illustrations, and photographs, and showcases cutting-edge translational research not included in the first edition. The broader scope of information in this text is essential reading for gynecologic surgeons, oncologists, pathologists, and molecular biologists.
Автор: Godfrey Grech; Iris Grossman Название: Preventive and Predictive Genetics: Towards Personalised Medicine ISBN: 3319380575 ISBN-13(EAN): 9783319380575 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Targeted therapy and reliable prediction of expected outcomes offer patients access to better healthcare management, by way of identifying the therapies effective for the relevant patient group, avoiding prescription of unnecessary treatment and reducing the likelihood of developing adverse drug reactions.
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