Steroid-Protein Interactions II, Ulrich Westphal

Автор: Veldhuis
Название: Sex-steroid Interactions With Growth Hormone.1999
ISBN: 0387988106 ISBN-13(EAN): 9780387988108
Издательство: Springer
Цена: 5974.00 р.
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Описание: Sex-Steroid Interactions with Growth Hormone presents the proceedings of an international symposium held from October 22-25 in Naples, Florida. The proceedings provide new insights and concepts gained by molecular, cellular and neuroendocrine research into mechanistic interactions of the reproductive and somatotrophic axes. Chapters include discussions of the impact of sex steroids on growth hormone secretion in both children and adults; sex steroids, growth hormone releasing factor, and somatostatin; how sex steroids modulate growth hormone action on target issues; and differential effects of growth hormone secretagogues in men and women. This volume is designed for physicians, scientists and other health professionals interested or trained in clinical and basic endocrinology, growth or reproduction.

Автор: William L. Duax
Название: Atlas of Steroid Structure
ISBN: 1475704283 ISBN-13(EAN): 9781475704280
Издательство: Springer
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Описание: By decreasing the temperature at which data is collected, the intensities and number of data observed is increased. Finally, in the absence of systematic errors in data collection or refinement, tae greater the number of observed data relative to the number of independent atoms, the better the atomic resolution will be.

Автор: Jack R. Jr. Lancaster; J.F. Parkinson
Название: Nitric Oxide, Cytochromes P450, and Sexual Steroid Hormones
ISBN: 3662035057 ISBN-13(EAN): 9783662035054
Издательство: Springer
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Описание: The discovery of mammalian nitric oxide (NO-) synthesis from I-ar- ginine has led to profound increases in our understanding of basic physiological and pathophysiological processes. This understanding has been achieved by major advances in several areas. Three major ni- tric oxide synthase (NOS) isoforms have been identified at the protein and gene level and their specific tissue localization has been linked to processes subject to regulation by NO-. The molecular basis for the di- verse effects of NO- on cell function has been shown to derive from its chemical reactivity with oxygen-containing species and both heme and non-heme iron-dependent enzymes. The potential regulation of heme- dependent enzymes such as cytochromes P450, guanylate cyclase, cy- clooxygenase, and mitochondrial cytochrome oxidase continues to emerge as a key area in NO- research. In addition, it has become clear that the expression of NOS isoforms and NO- release from cells is subject to regulation by sexual steroids and that, in tum, NO- has the potential to regulate steroid biosynthesis via inhibition of cytochromes P450 involved in steroidogenesis. These recent observations on interactions between the NO-/NOS and cytochrome P450/sexual steroid pathways have important implica- tions for understanding fundamental mechanisms involved in endocri- nological processes. They are also likely to lead to novel insights and novel therapeutic approaches for the management of pathophysiologi- cal conditions associated with alterations in sexual steroid hormones.

Автор: Lieberman Benjamin A.
Название: Steroid Receptor Methods / Protocols and Assays
ISBN: 0896037541 ISBN-13(EAN): 9780896037540
Издательство: Springer
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Цена: 21661.00 р.
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Описание: A distinguished team of principal investigators and their associates describe in step-by-step detail a cross-section of the latest research techniques available for studying the endocrine system. As a basis for sophisticated biochemical analysis of receptor properties, the contributors provide methods for the production and purification of a variety of receptors, including progesterone, glucocorticoid, and androgen. Other protocols allow the reader to experiment with DNA binding characteristics, hormone binding assays, and the use of combinatorial chemistry for drug discovery. A series of novel methods utilizing the latest advances in immunochemistry, yeast two-hybrid screening, and fluorescence are included for the detection and analysis of a variety of cellular proteins that influence steroid receptor effectiveness.

Автор: Johannes D. Veldhuis; Andrea Giustina
Название: Sex-Steroid Interactions with Growth Hormone
ISBN: 1461271878 ISBN-13(EAN): 9781461271871
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Sex-Steroid Interactions with Growth Hormone presents the proceedings of an international symposium held from October 22-25 in Naples, Florida. Chapters include discussions of the impact of sex steroids on growth hormone secretion in both children and adults; how sex steroids modulate growth hormone action on target issues;

Автор: Cheryl S. Watson
Название: The Identities of Membrane Steroid Receptors
ISBN: 146135028X ISBN-13(EAN): 9781461350286
Издательство: Springer
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Цена: 13974.00 р.
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Описание: New experimental tools have been brought to bear on the topic of receptors for steroids which mediate non-genomic actions, and thus investigative activity and focus regarding this type of steroid receptor has recently increased significantly.

Автор: Viqar Uddin Ahmad; Anwer Basha
Название: Spectroscopic Data of Steroid Glycosides
ISBN: 1441921702 ISBN-13(EAN): 9781441921703
Издательство: Springer
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Цена: 58557.00 р.
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Описание: This book is an essential reference guide to spectroscopic, physical and biological activity data of over 3500 steroid glycosides, offering the structures and the data of the naturally occurring glycosides of steroids.

Автор: Benjamin A. Lieberman
Название: Steroid Receptor Methods
ISBN: 161737170X ISBN-13(EAN): 9781617371707
Издательство: Springer
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Цена: 21661.00 р.
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Описание: Because the steroid receptor family is represented by a wonderfully diverse, yet strongly interrelated set of steroid receptor proteins, Steroid Receptor Methods contains protocols for the prod- tion and purification of a variety of receptor forms, including the progesterone, glucocorticoid, and androgen receptors.

Автор: Thomas C. Spelsberg; Rajiv Kumar
Название: Steroid and Sterol Hormone Action
ISBN: 1461292301 ISBN-13(EAN): 9781461292302
Издательство: Springer
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Цена: 34799.00 р.
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Описание: The purpose of this book is to focus attention on recent developments in steroid and sterol hormone action. Steroid hormone recep tor research and the study of nuclear events mediated by steroids are presently the most intensely studied aspects of sterol hormone action and our selection of topics reflects this trend.

Автор: Castoria
Название: Advances in Rapid Sex-Steroid Action
ISBN: 1489989358 ISBN-13(EAN): 9781489989352
Издательство: Springer
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Цена: 26552.00 р.
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Описание: This book examines how rapid steroid actions not only impact disease development and response to conventional therapies for breast and prostate cancers, but have also led to the identification of potential new therapeutic targets and treatment possibilities.

Автор: Kerry L. Burnstein
Название: Steroid Hormones and Cell Cycle Regulation
ISBN: 1461353270 ISBN-13(EAN): 9781461353270
Издательство: Springer
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Описание: From the tissue culture dish to genetically modified mice, this volume explores the long recognized role of steroid hormones in regulating cell proliferation and differentiation.

Автор: Virinder Moudgil
Название: Steroid Receptors in Health and Disease
ISBN: 1468455435 ISBN-13(EAN): 9781468455434
Издательство: Springer
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Описание: During the last two decades, progress in steroid hormone research has resulted in the development of new approaches to contraception as well as diagnosis and treatment of endocrine disorders and cancers.