Автор: Thorsteinn Loftsson Название: Essential Pharmacokinetics ISBN: 0128014113 ISBN-13(EAN): 9780128014110 Издательство: Elsevier Science Рейтинг: Цена: 8983.00 р. Наличие на складе: Поставка под заказ.
Описание: Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists is an introduction to the concepts of pharmacokinetics intended for graduate students and new researchers working in the pharmaceutical sciences. This book describes the mathematics used in the mammillary model as well as the application of pharmacokinetics to pharmaceutical product development, and is useful as both a self-study and classroom resource. Content coverage includes detailed discussions of common models and important pharmacokinetic concepts such as biological half-life, clearance, excretion, multiple dosage regimens and more. Numerous equations, practical examples and figures are incorporated to clearly illustrate the theoretical background of pharmacokinetic behavior of drugs and excipients.
Описание: This unique text helps students and healthcare professionals master the fundamentals of pharmacokinetics and pharmacodynamics. Written by distinguished international experts, it provides readers with an introduction to the basic principles underlying the establishment and individualization of dosage regimens and their optimal use in drug therapy. Up-to-date examples featuring currently prescribed drugs illustrate how pharmacokinetics and pharmacodynamics relate to contemporary drug therapy. Study problems at the end of each chapter help students and professionals gain a firm grasp of the material covered within the text.
Автор: Bauer Название: Handbook of clinical pharmacokinetics ISBN: 007142542X ISBN-13(EAN): 9780071425421 Издательство: McGraw-Hill Рейтинг: Цена: 6347.00 р. Наличие на складе: Поставка под заказ.
Описание: Designed for pharmacists and clinicians responsible for adjusting drug dosages based on the patient blood serum concentrations and other parameters, this indispensable, portable reference offers a variety of ways to perform pharmacokinetic calculations. It also features calculation methods, algorithms for choosing the best calculation method, and case studies.
Название: Drug Metabolism, Pharmacokinetics and Bioanalysis ISBN: 3038979163 ISBN-13(EAN): 9783038979166 Издательство: Неизвестно Рейтинг: Цена: 9409.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Drug metabolism/pharmacokinetics and drug interaction studies have been extensively carried out in order to secure the druggability and safety of new chemical entities throughout the development of new drugs. Recently, drug metabolism and transport by phase II drug metabolizing enzymes and drug transporters, respectively, as well as phase I drug metabolizing enzymes, have been studied. A combination of biochemical advances in the function and regulation of drug metabolizing enzymes and automated analytical technologies are revolutionizing drug metabolism research. There are also potential drug-drug interactions with co-administered drugs due to inhibition and/or induction of drug metabolic enzymes and drug transporters. In addition, drug interaction studies have been actively performed to develop substrate cocktails that do not interfere with each other and a simultaneous analytical method of substrate drugs and their metabolites using a tandem mass spectrometer. This Special Issue has the aim of highlighting current progress in drug metabolism/pharmacokinetics, drug interactions, and bioanalysis.
Описание: Updated with the latest clinical advances, Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics, Fifth Edition, explains the relationship between drug administration and drug response, taking a conceptual approach that emphasizes clinical application rather than science and mathematics. Bringing a real-life perspective to the topic, the book simplifies concepts and gives readers the knowledge they need to better evaluate drug applications.
Key updates reflect advances in PK/PD as related to clinical decision making and drug research and development.
An emphasis on the clinical relevance of drugs makes the book especially applicable to pharmacy students preparing for a career in clinical practice.
Hundreds of graphs and tables provide visual representations of key pharmacokinetic/pharmacodynamic principles and effects.
More than 200 carefully written study questions, with answers and in-depth explanations, help readers enhance their conceptual understanding and learn and retain key information.
New and updated examples connect chapter content to real-world settings.
Interactive online simulations give students practice using different pharmacokinetic/pharmacodynamic models and parameters.
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Описание: In the pharmaceutical industry, the incorporation of the disciplines of pharma- kinetics, pharmacodynamics, and drug metabolism (PK/PD/DM) into various drug development processes has been recognized to be extremely important for approp- ate compound selection and optimization.
Автор: Tekade, Rakesh K. Название: Biopharmaceutics And Pharmacokinetics Considerations ISBN: 0128144254 ISBN-13(EAN): 9780128144251 Издательство: Elsevier Science Рейтинг: Цена: 26444.00 р. Наличие на складе: Поставка под заказ.
Описание:
Biopharmaceutics and Pharmacokinetics Considerations examines the history as well as the current state of the field within pharmaceutical sciences and concisely explains the history of biopharmaceutics and pharmacokinetics including key developments. It provides a biopharmaceutics and pharmacokinetics approach to addressing issues in formulation development and ethical considerations in handling animals. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biopharmaceutics and pharmacokinetics within drug discovery and drug development. Each chapter delves into a particular aspect of this fundamental field to cover the principles, methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to study the chemical and physical properties of drugs and the biological effects they produce as well as the movement of drugs within the body. This book provides a comprehensive examination suitable for researchers working in the pharmaceutical, cosmetics, biotechnology, and related industries as well as advanced students in these fields.
Автор: Tozer Название: Essent Pharmacokinetics 2E Vst Xml Ebook ISBN: 1496325958 ISBN-13(EAN): 9781496325952 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 7864.00 р. Наличие на складе: Поставка под заказ.
Автор: Hedaya, Mohsen A. , Puri, Basant K. Название: Making Sense of Pharmacokinetics and Pharmacodynamics ISBN: 0367140934 ISBN-13(EAN): 9780367140939 Издательство: Taylor&Francis Рейтинг: Цена: 8419.00 р. Наличие на складе: Поставка под заказ.
Описание: Making Sense of Pharmacokinetics and Pharmacodynamics has been written as a practical and accessible guide to help the student and more experienced practitioner navigate these complex areas in order to understand better how drugs work and how, in turn, this knowledge underpins appropriate prescribing decisions.
Автор: Aldo Rescigno Название: Foundations of Pharmacokinetics ISBN: 1475787391 ISBN-13(EAN): 9781475787399 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book has its origin in my experience as a teacher of pharmacokinetics in many universities in four different continents. Chapters 13 to 17 show how different parameters of importance in pharmacokinetics can be exactly defined and measured.
Автор: Wagner, John G. Название: Pharmacokinetics for the Pharmaceutical Scientist ISBN: 0367402408 ISBN-13(EAN): 9780367402402 Издательство: Taylor&Francis Рейтинг: Цена: 9798.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A major presentation of pharmacokinetics by a leading international expert, this is a complete book on modeling the pharmacokinetics of drugs. It provides methods for: estimating drug disposition parameters from data obtained after intravascular or extravascular drug administration, estimating rate and extent of drug bioavailability, and comparing rate and extent of drug availability following administration of several different dosage forms of a drug. Authored by one of the founders of the field and written with insight that can only be obtained from years of experience, it is one of the very few advanced texts in the field.
Автор: Hedaya Mohsen A. Название: Basic Pharmacokinetics, Second Edition ISBN: 1439850739 ISBN-13(EAN): 9781439850732 Издательство: Taylor&Francis Рейтинг: Цена: 15310.00 р. Наличие на складе: Поставка под заказ.
Описание: Knowledge of pharmacokinetics is critical to understanding the absorption, distribution, metabolism, and excretion of drugs. Accessible to a wide variety of readers, this volume demonstrates the quantitative pharmacokinetic relations and the interplay between pharmacokinetic parameters. Accompanying the book are downloadable resources with self-
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