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Natural Antimicrobial Agents, Jean-Michel M?rillon; C?line Riviere


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Автор: Jean-Michel M?rillon; C?line Riviere
Название:  Natural Antimicrobial Agents
ISBN: 9783030097868
Издательство: Springer
Классификация:




ISBN-10: 3030097862
Обложка/Формат: Soft cover
Страницы: 337
Вес: 0.73 кг.
Дата издания: 2018
Серия: Sustainable Development and Biodiversity
Язык: English
Издание: Softcover reprint of
Иллюстрации: 85 tables, color; 13 illustrations, color; 37 illustrations, black and white; xi, 337 p. 50 illus., 13 illus. in color.
Размер: 236 x 218 x 15
Читательская аудитория: Professional & vocational
Основная тема: Life Sciences
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Documenting the latest research in the field of different pathogenic organisms, this book presents the current scenario about promising antimicrobials in the following areas: Part I. Plants as source of antibacterials, Part II. Naturally occurring antifungal natural products, Part III. Antiparasitic natural products, Part IV. Antiviral natural products. Renowned scientists from the globe have been selected as authors to contribute chapters. Use of plants for various ailments is as old as human civilization and continuous efforts are being made to improve medicinal plants or to product their bioactive secondary metabolites in high amounts through various technologies. About 200,000 natural products of plant origin are known and many more are being identified from higher plants and micro-organisms. Some plants based drugs are used since centuries and there is no alternative medicine for many such drugs as cardiac glycosides. Drug discovery from medicinal plants or marine micro-organisms continues to provide an important source of new drug leads. Research on new antibacterials represents a real and timely challenge of this century, particularly for the treatment of infections caused by clinical isolates that show multidrug resistance. The main microorganisms involved in the resistance process have been identified and given the acronym ESKAPE for Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumanii, Pseudomonas aeruginosa and Enterobacteriaceae. Multidrug resistant Mycobacterium tuberculosis including highly drug-resistant strains (XDR-TB) has also emerged as one of the most important clinical challenges of this century. Plants of diverse taxa and marine micro-organisms are rich source of these antimicrobials. An attempt has been made to compile the recent information about natural sources of antibacterials and their sustainable utilization. Increased panic of these pathogens warrants a growing demand for research to undertake the threat of multidrug resistance. The search for new antifungal, antiparasitic and antiviral natural products is far from devoid of interest. According to the WHO report in 2013, malaria still represents some 207 million cases worldwide and more than 3 billion of people are still exposed to this risk. Similarly, about 350 million people are considered at risk of contracting leishmaniasis. The fight against some viruses also requires that the research on natural products continue. For example, even if an antiretroviral with direct action was recently approved in Europe in 2013, its high cost does not allow to offer it to an exposed population in countries where the cost of drugs remains a problem for a large part of the population. These books are useful to researchers and students in microbiology, biotechnology, pharmacology, chemistry and biology as well as medical professionals.
Дополнительное описание: Part I. Plants as source of antibacterials.- 1. New antimicrobials and resistance modifying agents.- 2. Anti-staphylococcal plant natural products.- 3. Natural products in the fight against gram-negative bacteria.- 4. Multidrug resistance Mycobacterium an



Total Synthesis of Natural Products with Antimicrobial Activity

Автор: Giltrap
Название: Total Synthesis of Natural Products with Antimicrobial Activity
ISBN: 9811088055 ISBN-13(EAN): 9789811088056
Издательство: Springer
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Цена: 18167.00 р.
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Описание: This thesis focuses on the development of efficient and scalable total syntheses of natural products that can be used as preferred scaffolds for anti-infective drug discovery. It describes the total synthesis of two classes of antimicrobial non-ribosomal peptides (NRPs) – teixobactin and the skyllamycins – with subsequent biological evaluation. The first part describes the first total synthesis of teixobactin by means of a solid-phase peptide synthesis-macrolactamisation approach, yielding a synthetic natural product that can combat a number of clinically relevant Gram-positive bacterial pathogens. The second part describes the first total synthesis of skyllamycins A-C, a family of structurally complex cyclic NRPs, which inhibit the growth of the Pseudomonas aeruginosa biofilms that are responsible for significant mortality among cystic fibrosis patients.

Antimicrobial Susceptibility Testing

Автор: James A. Poupard; Lori R. Walsh; Bruce Kleger
Название: Antimicrobial Susceptibility Testing
ISBN: 1475792085 ISBN-13(EAN): 9781475792089
Издательство: Springer
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Цена: 20962.00 р.
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Описание: J ames Poupard Lori Walsh Bruee Kleger ix CONTENTS 1 Introduction 1: CURRENT METHODS The Evolution of Antimicrobial Susceptibility Testing Methods . Bartlett Areas of Recent Emphasis of the National Committee for Clinical Laboratory Standards Subcommittee on Antimicrobial Susceptibility Testing .

Total Synthesis of Natural Products with Antimicrobial Activity

Автор: Giltrap
Название: Total Synthesis of Natural Products with Antimicrobial Activity
ISBN: 9811342458 ISBN-13(EAN): 9789811342455
Издательство: Springer
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Цена: 18167.00 р.
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Описание: This thesis focuses on the development of efficient and scalable total syntheses of natural products that can be used as preferred scaffolds for anti-infective drug discovery.

Mechanism of Action of Antimicrobial and Antitumor Agents

Автор: J. F. Snell; J. W. Corcoran; K. L. Arora; F. E. Ha
Название: Mechanism of Action of Antimicrobial and Antitumor Agents
ISBN: 3642463061 ISBN-13(EAN): 9783642463068
Издательство: Springer
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Цена: 6986.00 р.
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Описание: This volume is the third in the series devoted to Antibiotics initiated by Springer Verlag in 1967.

Antimicrobial Agents: Antibacterials and Antifungals Agents 2005

Автор: Bryskier
Название: Antimicrobial Agents: Antibacterials and Antifungals Agents 2005
ISBN: 1555812376 ISBN-13(EAN): 9781555812379
Издательство: Wiley
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Цена: 18216.00 р.
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Описание: Offers many antibiotics and antimicrobial compounds: in development, experimental, and in use. This title covers chemistry and synthesis, classification, structure-activity relationships, mechanisms of action and resistance, breakpoints, in vitro/in vivo activities, epidemiology, pharmacokinetics, metabolism, and adverse events.

Antimicrobial Compounds

Автор: Villa Tomas G.
Название: Antimicrobial Compounds
ISBN: 364240443X ISBN-13(EAN): 9783642404436
Издательство: Springer
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Цена: 23508.00 р.
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Описание: This book reviews the current state-of-the-art in antimicrobial research and discusses new strategies for the design and discovery of novel therapies. It combines basic research with clinical applications.

Antimicrobial Peptides

Автор: Paul Robert Hansen
Название: Antimicrobial Peptides
ISBN: 1493967355 ISBN-13(EAN): 9781493967353
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This volume provides basic and advanced laboratory protocols for the non-specialist and the experienced researcher. Chapters are divided into three parts covering synthesis and characterization of AMPs, studying the interaction of AMPs with model systems or bacteria, and assaying selected biological activities of AMPs. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Antimicrobial Peptides: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Antimicrobial Nanoarchitectonics

Автор: Grumezescu, Alexander Mih
Название: Antimicrobial Nanoarchitectonics
ISBN: 0323527337 ISBN-13(EAN): 9780323527330
Издательство: Elsevier Science
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Цена: 26107.00 р.
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Описание:

Antimicrobial Nanoarchitectonics: From Synthesis to Applications brings together recent research in antimicrobial nanoparticles, specifically in the sustained and controlled delivery of antimicrobials. Particular attention is given to i) reducing the side effects of antibiotics, ii) increasing the pharmacological effect, and iii) improving aqueous solubility and chemical stability of different antimicrobials. In addition, antimicrobial nanoparticles in drug delivery are discussed extensively. The book also evaluates the pros and cons of using nanostructured biomaterials in the prevention and eradication of infections. It is an important reference resource for materials scientists and bioengineers who want to learn how nanomaterials are used in antimicrobial therapy.


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