Developmental Human Behavioral Epigenetics, Provenzi, Livio
Автор: Tollefsbol Trygve Название: Epigenetics in Human Disease ISBN: 0128122153 ISBN-13(EAN): 9780128122150 Издательство: Elsevier Science Рейтинг: Цена: 23075.00 р. Наличие на складе: Нет в наличии.
Описание: Epigenetics in Human Disease, Second Edition examines the diseases and conditions on which we have advanced knowledge of epigenetic mechanisms, such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders and cardiovascular disease. In addition to detailing the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, novel epigenetic approaches to treatment are also explored. Fully revised and up-to-date, this new edition discusses topics of current interest in epigenetic research, including stem cell epigenetic therapy, bioinformatic analysis of NGS data, and epigenetic mechanisms of imprinting disorders.
Further sections explore online epigenetic tools and datasets, early-life programming of epigenetics in age-related diseases, the epigenetics of addiction and suicide, and epigenetic approaches to regulating and preventing diabetes, cardiac disease, allergic disorders, Alzheimer's disease, respiratory diseases, and many other human maladies.
Автор: Johannes Backs, Timothy McKinsey Название: Epigenetics in Cardiac Disease ISBN: 3319414550 ISBN-13(EAN): 9783319414553 Издательство: Springer Рейтинг: Цена: 14673.00 р. 20962.00-30% Наличие на складе: Нет в наличии.
Описание: This book describes important advances in our understanding of how environmental conditions affect cardiac gene expression through epigenetic mechanisms. Further, it discusses the roles of chromatin modifications (in particular DNA methylation and histone modifications) and of chromatin regulators in the context of cardiac diseases. The book provides readers with an overview of our current understanding of epigenetic regulation in the heart, and will stimulate further research in this exciting field. Edited and written by internationally respected experts, it addresses the needs of professors, students and researchers working in the fields of cardiac biology and epigenetics.
Автор: Trygve Tollefsbol Название: Medical Epigenetics ISBN: 0128032391 ISBN-13(EAN): 9780128032398 Издательство: Elsevier Science Рейтинг: Цена: 22696.00 р. Наличие на складе: Нет в наличии.
Описание: "
Medical Epigenetics" is an inclusive volume on the medical aspects of epigenetics with a focus on human systems, epigenetic disease that affect these systems, and modes of treating epigenetic-based disorders and diseases. This book provides stand-alone coverage of all human systems relevant to epigenetic maladies and all major aspects of medical epigenetics. It is useful not only to physicians, nurses, medical students, and many others directly involved with healthcare, but also investigators in life sciences, biotech companies, graduate students, and all others who are interested in more applied aspects of epigenetics.
The expansion of the field of epigenetics has brought a wealth of information with respect to variations in phenotypes that are heritable. In addition, many advances have emerged that have shown epigenetic aberrations as central to a number of diseases and disorders that were previously thought to be manifested primarily through genetic factors. Along with the remarkable studies that have been made in our understanding of epigenetic-based diseases and disorders has come new information that allows treatments that target these many epigenetic aberrations. "Medical Epigenetics" brings all of this knowledge together to comprehensively review the state of medical epigenetics in one defining volume.
The basic design of "Medical Epigenetics" is to lead the reader from the fundamental mechanisms of epigenetics as they apply to humans through approaches for treating epigenetic-based diseases. This book begins with the basic tenets of epigenetics in human systems and progresses through general medical aspects of epigenetics, epigenetics or system disorders, multi-system medical epigenetics, pharmacology of epigenetics, and therapeutic epigenetics. "Medical Epigenetics" closes with a chapter on future prospects in medical epigenetics. This book is by far the most complete book in the area of applied epigenetics. Focuses on practical and applied aspects of medical epigeneticsIncludes peer-reviewed chapters with up-to-date coverage of emerging topics in medical epigenetics by leading expertsAppeals to those interested in fundamental epigenetics and inheritance, as well as those with more clinical interests including practicing physicians and other health care professionalsCovers the basic tenets of epigenetics in human systems and progresses through general medical aspects of epigenetics, epigenetics or system disorders, multi-system medical epigenetics, pharmacology of epigenetics, and therapeutic epigenetics
Автор: Tollefsbol, Trygve Название: The Epigenetics of Autoimmunity ISBN: 0128099127 ISBN-13(EAN): 9780128099124 Издательство: Elsevier Science Рейтинг: Цена: 23917.00 р. Наличие на складе: Нет в наличии.
Описание: The Epigenetics of Autoimmunity covers a topic directly related to translational epigenetics. Via epigenetic mechanisms, a number of internal and external environmental risk factors, including smoking, nutrition, viral infection and the exposure to chemicals, could exert their influence on the pathogenesis of autoimmune diseases. Such factors could impact the epigenetic mechanisms, which, in turn, build relationship with the regulation of gene expression, and eventually triggering immunologic events that result in instability of immune system. Since epigenetic aberrations are known to play a key role in a long list of human diseases, the translational significance of autoimmunity epigenetics is very high. . To bridge the gap between environmental and genetic factors, over the past few years, great progress has been made in identifying detailed epigenetic mechanisms for autoimmune diseases. Furthermore, with rapid advances in technological development, high-throughput screening approaches and other novel technologies support the systematic investigations and facilitate the epigenetic identification. This book covers autoimmunity epigenetics from a disease-oriented perspective and several chapters are presented that provide advances in wide-spread disorders or diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), multiple sclerosis (MS), type 1 diabetes (T1DM), systemic sclerosis (SSc), primary Sj?gren's syndrome (pSS) and autoimmune thyroid diseases (AITDs). . These emerging epigenetic studies provide new insights into autoimmune diseases, raising great expectations among researchers and clinicians. This seminal book on this topic comprehensively covers the most recent advances in this exciting and rapidly developing new science. They might reveal not only new clinical biomarkers for diagnosis and disease progression, but also novel targets for potential epigenetic therapeutic treatment.
Автор: Waddington Название: The Epigenetics of Birds ISBN: 1107440475 ISBN-13(EAN): 9781107440470 Издательство: Cambridge Academ Рейтинг: Цена: 5859.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Originally published in 1952 as part of the Cambridge Biological Studies series, this book presents contemporary theories on embryology using the example of the bird embryo. Waddington reviews the modern experimental embryology of birds, and touches on topics such as plumage development and the developmental actions of mutant genes.
Описание: An accessible introduction to behavioral epigenetics, The Developing Genome explores how experiences influence genetic activity. We develop as we do not because of the genes we have, but because of what our genes do.
Описание: For as much as we know about DNA and gene expression, many more mysteries remain to be solved. Epigenetics and epigenomics seek to study heritable modifications in gene expression that do not involve underlying DNA sequences to further human health changes. Examining the Causal Relationship Between Genes, Epigenetics, and Human Health provides innovative research methods and applications of chemical activation or deactivation of genes without altering the original DNA sequence. While highlighting topics including gene expression, personalized medicine, and public policy, this book is ideal for researchers, geneticists, biologists, medical professionals, students, and academics seeking current research on the expanding fields of genomics, epigenomics, proteomics, pharmacogenomics, and genome-wide association studies.
Автор: Drew Augustus Название: Epigenetics and Human Health ISBN: 1632416522 ISBN-13(EAN): 9781632416520 Издательство: Неизвестно Рейтинг: Цена: 23335.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Carsten Carlberg; Ferdinand Moln?r Название: Human Epigenetics: How Science Works ISBN: 3030229068 ISBN-13(EAN): 9783030229061 Издательство: Springer Рейтинг: Цена: 10480.00 р. Наличие на складе: Нет в наличии.
Описание: The first five chapters explain the molecular basis of epigenetics, while the following seven chapters provide examples for the impact of epigenetics in human health and disease.
Автор: Rousseaux Название: Epigenetics and Human Reproduction ISBN: 3642147720 ISBN-13(EAN): 9783642147722 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans. Edited by preeminent experts, Sophie Rousseaux and Saadi Khochbin, this volume in the ‘Epigenetics and Human Health’ series discusses the role of epigenetics in human reproduction
Автор: Trygve Tollefsbol Название: Epigenetics in Human Disease, ISBN: 0123884152 ISBN-13(EAN): 9780123884152 Издательство: Elsevier Science Цена: 16506.00 р. Наличие на складе: Нет в наличии.
Описание:
Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable, attempts are made to not only detail the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, but also novel epigenetic approaches to the treatment of these diseases. Chapters are also presented on human imprinting disorders, respiratory diseases, infectious diseases and gynecological and reproductive diseases. Since epigenetics plays a major role in the aging process, advances in the epigenetics of aging are highly relevant to many age-related human diseases. Therefore, this volume closes with chapters on aging epigenetics and breakthroughs that have been made to delay the aging process through epigenetic approaches. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike. Comprehensive coverage of fundamental and emergent science and clinical usageSide-by-side coverage of the basis of epigenetic diseases and their treatmentsEvaluation of recent epigenetic clinical breakthroughs
Автор: Sophie Rousseaux; Saadi Khochbin Название: Epigenetics and Human Reproduction ISBN: 3642265820 ISBN-13(EAN): 9783642265822 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The rapidly expanding field of epigenetics examines heritable traits that are not attributable to changes in the DNA sequence. Edited by two preeminent experts, this volume is part of a wider series and analyzes the role of epigenetics in human reproduction.
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