Crispr Genome Surgery In Stem Cells And Disease Tissues, Tsang, Stephen H.
Автор: Swerdlow S., Campo E., Harris N. L. Название: WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. Revized 4 ed. ISBN: 928324494X ISBN-13(EAN): 9789283244943 Издательство: WHO Press Рейтинг: Цена: 16294.00 р. 23277.00-30% Наличие на складе: Есть (3 шт.) Описание: ****When not purchasing directly from the official sales agents of the WHO, especially at online bookshops, please note that there have been issues with counterfeited copies. Buy only from known sellers and if there are quality issues, please contact the seller for a refund.***** WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues is a Revised Fourth Edition of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants further include new ICD-O codes, epidemiology, clinical features, macroscopy, prognosis, and predictive factors. This classification, prepared by 132 authors from 23 countries, contains about 1300 color images and tables and more than 4500 references.
Автор: S.H Swerdlow Название: WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues ISBN: 9283224310 ISBN-13(EAN): 9789283224310 Издательство: WHO Press Рейтинг: Цена: 9018.00 р. Наличие на складе: Есть (2 шт.) Описание: WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue is the third volume in the new WHO series on histological and genetic typing of human tumors. This authoritative, concise reference book covers the entire range of leukaemias and lymphomas. It provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, incidence, age and sex distribution, location, clinical signs and symptoms, pathology, genetics, and predictive factors.
The book, prepared by 130 authors from 22 countries, contains more than 1,000 color photographs, numerous magnetic resonance and ultrasound images, CT scans, charts, and 2,500 references.
This book is in the series commonly referred to as the "Blue Book" series.
Contributors: Dr Cem Akin, Dr Loannis Anagnostopoulos, Dr Katsuyuki Aozasa, Dr Daniel A. Arber, Dr Michele Baccarani, Dr Barbara J. Bain, Dr Giovanni Barosi, Dr Lrith Baumann, Dr Marie-Christine Bene, Dr Daniel Benharroch, Dr John M. Bennett, Dr Francoise Berger, Dr Emillo Berti, Dr Gunnar Birgegard, Dr Clara D. Bloomfield, Dr Bettina Borisch, Dr Michael J. Borowitz, Dr Richard D. Brunning, Dr Walter Burgdorf, Dr Elias Campo, Dr Daniel Catovsky, Dr Lorenzo Cerroni, Dr Ethel Cesarman, Dr Amv Chadburn, Dr John K.C. Chan, Dr Wing Chung Chan, Dr Andreas Chott, Dr Robert W. Coupland, Dr Daphne De Jong, Dr Christiane De Wolf-Peeters, Dr Martina Deckert, Dr Jan Delabie, Dr Georges Delsol, Dr Ahmet Dogan, Dr Lyn M. Duncan, Dr Kojo S.J. Elenitoba-Johnson, Dr Luis Escribano, Dr Fabio Facchetti, Dr Brunangelo Falini, Dr Judith A. Ferry, Dr Christopher D.M. Fletcher, Dr Katheryn Foucar, Dr Randy D. Gascoyne, Dr Kevin C. Gatter, Dr Norbert Gattermann, Dr Phillippe Gaulard, Dr Ulrich Germing, Dr D. Gary Gilliland, Dr Heinz Gisslinger, Dr Peter L. Greenberg, Dr Thomas M. Grogan, Dr. Karen L. Grogg, Dr Margarita Guenova, Dr Nancy Lee Harris, Dr Robert Paul Hasserjian, Dr Eva Hellstrom-Lindberg, Dr Hans-Peter Horny, Dr Peter G. Isaacson, Dr Elaine S. Jaffe, Dr Ronald Jaffe, Dr Daniel M. Jones, Dr Marshall E. Kadin, Dr Masahiro Kikuchi, Dr Hiroshi Kimura, Dr Marsha C. Kinney, Dr Phillip M. Kluin, Dr Young-Hyeh Ko, Dr Alla M. Kovrigina, Dr Laszlo Krenacs, Dr W. Michael Kuehl, Dr Jeffery L. Kutok, Dr Hans Michael Kvasnicka, Dr Robert A. Kyle, Dr Richard A. Larson, Dr Michelle M. Le Beau, Dr Lorenzo Leoncini, Dr Alan F. List, Dr Kenneth A. Maclennan, Dr William R. Macon, Dr David Y. Mason, Dr Estella Matutes, Dr Robert W. Mckenna, Dr Chris J.L.M. Meijer, Dr Junia V. Melo, Dr Dean D. Metcalfe, Dr Manuela Mollejo, Dr Peter Moller, Dr Emilli Montserrat, Dr William G. Morice, Dr Hans Konrad Muller-Hermelink, Drshigeo Nakamura, Dr Bharat N. Nathwani, Dr Charlotte M. Niemeyer, Dr Hiroko Ohgaki, Dr Kiochi Ohshima, Dr Mihaela Onciu, Dr Atillio Orazi, Dr German Ott, Dr Marco Paulli, Dr Suat-Cheng Peh, Dr Loann Peterson, Dr Tony Petrella, Dr Stefano A. Pileri, Dr Miguel A. Piris, Dr Stefania Pittaluga, Dr Maurillio Ponzoni, Dr Sibrand Poppema, Dr Anna Porwit, Dr Leticia Quintanilla-Martinez, Dr Elisabeth Ralfiaker, Dr Martine Raphael, Dr Jonathan Said, Dr Christian A. Sander, Dr Masao Seto, Dr Kevin Shannon, Dr Bruce R. Smoller, Dr Ivy Sng, Dr Dominic Spagnolo, Dr Harald Stein, Dr Christer Sundstrom, Dr Steven H. Swerdlow, Dr Ayalew Tefferi, Dr Catherine Thieblemont, Dr Jurgen Thiele, Dr Peter Valent, Dr J.H. Van Krieken, Dr James W. Vardiman, Dr Beatrice Vergier, Dr Neus Villamor, Dr Reinhard Von Wasielewski, Dr Roger A. Warnke, Dr Steven A. Webber, Dr Dennis D. Weisenburger, Dr Lawrence M. Weiss, Dr Sean J. Whittaker, Dr Rein Willemze, Dr Wyndham H. Wilson, D
Название: Genome engineering via crispr-cas9 system ISBN: 0128181400 ISBN-13(EAN): 9780128181409 Издательство: Elsevier Science Рейтинг: Цена: 23075.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Genome Engineering via CRISPR-Cas9 Systems presents a compilation of chapters from eminent scientists from across the globe who have established expertise in working with CRISPR-Cas9 systems. Currently, targeted genome engineering is a key technology for basic science, biomedical and industrial applications due to the relative simplicity to which they can be designed, used and applied. However, it is not easy to find relevant information gathered in a single source. The book contains a wide range of applications of CRISPR in research of bacteria, virus, algae, plant and mammalian and also discusses the modeling of drosophila, zebra fish and protozoan, among others.
Other topics covered include diagnosis, sensor and therapeutic applications, as well as ethical and regulatory issues. This book is a valuable source not only for beginners in genome engineering, but also researchers, clinicians, stakeholders, policy makers, and practitioners interested in the potential of CRISPR-Cas9 in several fields.
Автор: Bailey, Scott Название: CRISPR-Cas Enzymes ISBN: 0128167602 ISBN-13(EAN): 9780128167601 Издательство: Elsevier Science Рейтинг: Цена: 24423.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: CRISPR-Cas Enzymes, Volume 616, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered in this release include CRISPR bioinformatics, A method for one-step assembly of Class 2 CRISPR arrays, Biochemical reconstitution and structural analysis of ribonucleoprotein complexes in Type I-E CRISPR-Cas systems, Mechanistic dissection of the CRISPR interference pathway in Type I-E CRISPR-Cas system, Site-specific fluorescent labeling of individual proteins within CRISPR complexes, Fluorescence-based methods for measuring target interference by CRISPR-Cas systems, Native State Structural Characterization of CRISRP Associated Complexes using Mass Spectrometry, and more.
Описание: With the advent of CRISPR gene-editing technology, designer babies have become a reality. Francoise Baylis insists that scientists alone cannot decide the terms of this new era in human evolution. Members of the public, with diverse interests and perspectives, must have a role in determining our future as a species.
CRISPR in Animals and Animal Models, Volume 152, the latest release in the Progress in Molecular Biology and Translational Science series, explores the genome editing CRISPR system in cells and animal models, its applications, the uses of the CRISPR system, and the past, present and future of CRISPR genome editing. Topics of interest in this updated volume include a section on CRISPR history, The genome editing revolution, Programming CRISPR and its applications, CRISPR Delivery methods, CRISPR libraries and screening, CRISPR investigation in haploid cells, CRISPR in the generation of transgenic animals, CRISPR therapeutics, and Promising strategies and present challenges.
Описание: This volume provides readers with wide-ranging coverage of CRISPR systems and their applications in various plant species. The chapters in this book discuss topics such as plant DNA repair and genome editing; analysis of CRISPR-induced mutations; multiplexed CRISPR/Cas9 systems; CRISPR-Cas12a (Cpf1) editing systems; and non-agrobacterium based CRISPR delivery systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and thorough, Plant Genome Editing with CRISPR Systems: Methods and Protocols is a valuable resource for any researcher interested in learning about and using CRISPR systems in plants.
Автор: Stephen Tsang; George M. Church Название: Precision Medicine, CRISPR, and Genome Engineering ISBN: 331963903X ISBN-13(EAN): 9783319639031 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents descriptive overviews of gene editing strategies across multiple species while also offering in-depth insight on complex cases of application in the field of tissue engineering and regenerative medicine.
Название: Crispr/cas9 system: applications and technology ISBN: 1536164267 ISBN-13(EAN): 9781536164268 Издательство: Nova Science Рейтинг: Цена: 13462.00 р. Наличие на складе: Невозможна поставка.
Описание: This compilation focuses on the CRISPR/Cas9 system, a genome editing tool that has been hailed as the most profound molecular biology discovery in the past decade. By employing the natural process of bacterial immunity towards bacteriophages, the tool allows researchers to precisely excise and edit parts of the genetic sequence to modify them. The authors summarize the molecular pathogenesis of hepatocellular carcinoma, available treatments/drugs and their limitations, the landscape of CRISPR targeting hepatocellular carcinoma, limitations and potential targets in future. The closing review summarises the use of CRISPR/Cas9 gene editing in ophthalmology and focuses on the advancement of gene editing in the cornea. The majority of corneal dystrophies are the result an autosomal dominant inheritance pattern within the TGFBI gene, which presents an ideal model suited for a CRISPR/Cas9 knock out methodology.
Автор: Yonglun Luo Название: CRISPR Gene Editing ISBN: 1493991698 ISBN-13(EAN): 9781493991693 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This detailed volume guides readers through strategic planning and user-friendly guidelines in order to select the most suitable CRISPR-Cas system and target sites with high activity and specificity. Methods covering CRISPR gRNA design, CRISPR delivery, CRISPR activity quantification (indel quantification), and examples of applying CRISPR gene editing in human pluripotent stem cells, primary cells, gene therapy, and genetic screening are included. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and invaluable, CRISPR Gene Editing: Methods and Protocols will assist undergraduates, graduates, and researchers with detailed guidelines and methods for the vitally important CRISPR gene editing field.
Chapter 3 is available open access under a CC BY 4.0 license via link.springer.com.
Автор: Ridge Yolanda Название: Crispr: A Powerful Way to Change DNA ISBN: 1773214233 ISBN-13(EAN): 9781773214238 Издательство: Неизвестно Рейтинг: Цена: 1886.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
We can change the world with genetic modification--but should we?
CRISPR stands for clustered regularly interspaced short palindromic repeats. If it sounds complicated, it is--but it's also one of the most powerful ways we can shape the future. And it's poised to completely upend the way we think about science.
Author Yolanda Ridge tackles this topic in a friendly and accessible tone, with two introductory chapters covering the basics of DNA and genetic modification before taking readers through the ways that this ground-breaking science could affect them by potentially:
- eliminating diseases like malaria and cancer,
- improving the stability of our food supply, and
- helping to manage conservation efforts for threatened animals and environments.
But all of these possible advancements come with risks, the biggest being that the consequences are unknown. Chapters end with "Stop, Go, Yield" sections encouraging readers to consider the pros and cons of using CRISPR. "Cutting Questions" give readers the opportunity to further reflect on the ethics of the science.
CRISPR is a game changer. This important book, with detailed scientific illustrations, brings much needed clarity to a topic that will affect readers for generations to come.
Автор: Rodolphe Barrangou; John van der Oost Название: CRISPR-Cas Systems ISBN: 3642429297 ISBN-13(EAN): 9783642429293 Издательство: Springer Рейтинг: Цена: 32142.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered. In this book, experts summarize the state of the art in this exciting field.
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