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Discovery And Development Of Anti-Inflammatory Agents From Natural Products, Brahmachari, Goutam


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Цена: 28633.00р.
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Автор: Brahmachari, Goutam
Название:  Discovery And Development Of Anti-Inflammatory Agents From Natural Products
ISBN: 9780128169926
Издательство: Elsevier Science
Классификация:

ISBN-10: 0128169923
Обложка/Формат: Paperback
Страницы: 332
Вес: 0.52 кг.
Дата издания: 12.07.2019
Серия: Natural product drug discovery
Язык: English
Размер: 229 x 152 x 18
Ссылка на Издательство: Link
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Поставляется из: Европейский союз
Описание:

Discovery and Development of Anti-inflammatory Agents from Natural Products, the latest volume in the Natural Product Drug Discovery series, presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations, with this volume focusing on molecules of natural origin and their synthetic analogues that have the potential to act against the pathogens responsible for inflammatory diseases. All aspects of each are covered, including isolations and structure elucidations, in vitro and in vivo biological activity, synthetic optimization, investigations of pharmacodynamics and kinetics, and the structure-activity relationships of anti-inflammatory natural products.

Written by active researchers and leading experts, this book brings together an overview of current discoveries and trends in this field. It will be a valuable resource for researchers working to discover promising leads for the development of pharmaceuticals in the prevention and treatment of anti-inflammatory diseases.



Encyclopedia of Drug Discovery and Development: Volume VIII (Traditional and Innovative Solutions in Natural Drug Discovery)

Автор: Burnett Ned
Название: Encyclopedia of Drug Discovery and Development: Volume VIII (Traditional and Innovative Solutions in Natural Drug Discovery)
ISBN: 1632421437 ISBN-13(EAN): 9781632421432
Издательство: Неизвестно
Цена: 25747.00 р.
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Discovery and development of neuroprotective agents from natural products

Название: Discovery and development of neuroprotective agents from natural products
ISBN: 0128095938 ISBN-13(EAN): 9780128095935
Издательство: Elsevier Science
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Цена: 26949.00 р.
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Описание:

Discovery and Development of Neuroprotective Agents from Natural Products draws together global research on medicinal agents from natural sources as starting points for the design of neuroprotective drugs. From the prediction of promising leads and identification of active agents to the extraction of complex molecules, the book explores a range of important topics to support the development of safer, more economical therapeutics for these increasingly prevalent diseases.

Beginning with an overview of current developments in the field, the book goes on to explore the identification, extraction and phytochemistry of such neuroprotective agents as antioxidants, biophenols and naturally occurring anti-inflammatory steroid analogues. Specific natural sources of bioactive agents are reviewed, and the development of these agents into therapeutics for a number of specific neurological disorders, including Alzheimer's disease, Parkinson's disease and ischemic brain stroke, are discussed.

Combining the expertise of specialists from around the world, this in the Natural Products Drug Discovery series aims to support and encourage researchers in the investigation of natural sources as starting points for the development of standardized, safe and effective neuroprotective drugs.


  • Features chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery
  • Includes comprehensive coverage of cutting-edge research advances in the design of drugs from natural products targeted at different kinds of neurodegenerative diseases
  • Offers a practical review of identification, isolation and extraction techniques to support medicinal chemists in the lab
Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases

Автор: Brahmachari, Goutam
Название: Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases
ISBN: 0128157232 ISBN-13(EAN): 9780128157237
Издательство: Elsevier Science
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Цена: 28970.00 р.
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Описание:

Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting points for the design of drugs against Neglected Tropical Diseases (NTDs). From the prediction of promising leads and identification of active agents, to the extraction of complex molecules, the book explores novel, economical and efficacious therapeutics for these diseases. It describes current research and the role of natural products, antimalarial compounds from marine natural products and sesquiterpene lactones, natural antileprotic agents, natural products with potential against Leishmaniasis, Trypanosomiasis and Dengue, and more.

In addition, Quinoline and Isoquinoline alkaloids for developing new antiprotozoal agents are discussed, alongside anti-trypanosomatid heterocyclic compounds as structures for development. Combining the expertise of specialists from around the world, this volume aims to support and encourage researchers in the investigation of natural sources as starting points for the development of novel, safe and effective agents for use against neglected tropical diseases.

  • Includes chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery
  • Draws together cutting-edge research advances in natural product chemistry that are targeted at neglected tropical diseases
  • Highlights the future potential of natural products as sources of novel medicinal compounds against neglected tropical diseases
Discovery and Development of Antidiabetic Agents from Natural Pro

Автор: Brahmachari, Goutam
Название: Discovery and Development of Antidiabetic Agents from Natural Pro
ISBN: 0128094508 ISBN-13(EAN): 9780128094501
Издательство: Elsevier Science
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Цена: 23244.00 р.
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Описание:

Discovery and Development of Antidiabetic Agents from Natural Products brings together global research on the medicinal chemistry of active agents from natural sources for the prevention and treatment of diabetes and associated disorders. From the identification of promising leads, to the extraction and synthesis of bioactive molecules, this book explores a range of important topics to support chemists in the discovery and development of safer, more economical therapeutics that are desperately needed in response to this emerging global epidemic.

Beginning with an overview of bioactive chemical compounds from plants with anti-diabetic properties, the book goes on to outline the identification and extraction of anti-diabetic agents and antioxidants from natural sources. It then explores anti-diabetic plants from specific regions before looking more closely at the background, isolation, and synthesis of key therapeutic compounds and their derivatives, including Mangiferin, Resveratrol, natural saponins, and alpha-glucosidase enzyme inhibitors. The book concludes with a consideration of current and potential future applications.

Combining the expertise of specialists from around the world, this volume aims to support and encourage medicinal chemists investigating natural sources as starting points for the development of standardized, safe, and effective antidiabetic therapeutics.

Biological Efficacy of Natural and Chemically Modified Products against Oral Inflammatory Lesions

Название: Biological Efficacy of Natural and Chemically Modified Products against Oral Inflammatory Lesions
ISBN: 3038979929 ISBN-13(EAN): 9783038979920
Издательство: Неизвестно
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Цена: 9409.00 р.
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Описание:

Oral health is general health. If the oral cavity is kept healthy, the whole body is always healthy. Bacteria in the oral cavity do not stay in the oral cavity, but rather they travel throughout the body and can induce various diseases. Periodontal pathogens are involved in tooth loss. The number of remaining teeth decreases with age. People with more residual teeth can bite food well and live longer with lower incidence of dementia. There are many viruses in the oral cavity that also cause various diseases. Bacteria and viruses induce and aggravate inflammation, and therefore should be removed from the oral cavity. In the natural world, there are are many as yet undiscovered antiviral, antibacterial and anti-inflammatory substances. These natural substances, as well as chemically modified derivatives, help our oral health and lead us to more fulfilling, high quality lives. This Special Issue, entitled "Biological Efficacy of Natural and Chemically Modified Products against Oral Inflammatory Lesions", was written by specialists from a diverse variety of fields. It serves to provide readers with up-to-date information on incidence rates in each age group, etiology and treatment of stomatitis, and to investigate the application of such treatments as oral care and cosmetic materials.

Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Products

Автор: Taro Noguchi
Название: Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Products
ISBN: 9811066221 ISBN-13(EAN): 9789811066221
Издательство: Springer
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Цена: 15372.00 р.
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Описание: This thesis mainly describes the development of a screening process for a mirror-image library of chiral natural products. It demonstrates how, by using mirror-image proteins for the screening of available natural products, unavailable mirror-image isomers of natural products can be screened in a mirror process.

Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Products

Автор: Taro Noguchi
Название: Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Products
ISBN: 9811349177 ISBN-13(EAN): 9789811349171
Издательство: Springer
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Цена: 13974.00 р.
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Описание:

This thesis mainly describes the development of a screening process for a mirror-image library of chiral natural products. It demonstrates how, by using mirror-image proteins for the screening of available natural products, unavailable mirror-image isomers of natural products can be screened in a mirror process. Moreover, as mirror-image isomers including target proteins and natural products are mainly prepared by means of chemical synthesis, the screening strategy presented here suggests the importance of organic chemistry. Natural products are commonly used as valuable resources for drug discovery. However, as they are mostly produced as single enantiomeric forms, researchers have tested o
nly natural products bearing one stereochemistry available in nature. As natural products and their enantiomers have identical physicochemical properties and different biological activities, mirror-image isomers of natural products are promising candidates for novel medicinal resources. In an effort to identify anticancer agents from the mirror-image library, chemical protein syntheses of some target oncoproteins, MDM2, MDMX and Grb2, and their applications to the chemical array screening process were achieved. In the course of this process the NP843 enantiomer, which is the enantiomer of an ?-tocopherol derivative, was successfully identified as a novel MDM2-p53 interaction inhibitor. These results clearly show that a mirror-image library of chiral natural products represents an invaluable medicinal resource. Accordingly, the chemistry-based screening strategy described in this thesis will be of great interest to a broad range of chemists involved in natural product, medicinal, and synthetic chemistry.
Natural Products and Cancer Drug Discovery

Автор: Frank E. Koehn
Название: Natural Products and Cancer Drug Discovery
ISBN: 148999565X ISBN-13(EAN): 9781489995650
Издательство: Springer
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Цена: 22201.00 р.
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Описание: With reliable commentary and analysis in a sector often associated with outlandish claims, this volume provides a valuable overview of how natural products could generate new cancer therapeutics as well as mitigating the deleterious effects of chemotherapy.

The Role of Natural Products in Drug Discovery

Автор: J. Mulzer; R. Bohlmann
Название: The Role of Natural Products in Drug Discovery
ISBN: 3662040441 ISBN-13(EAN): 9783662040447
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Natural Products have been important sources of useful drugs from prehistoric times to the present. This book gives an overview about this field and provides important recent contributions to the discovery of new drugs generated by research on natural products.

Encyclopedia of Drug Discovery and Development: Volume III (Cancer Treatment and Anti-Infectives)

Автор: Burnett Ned
Название: Encyclopedia of Drug Discovery and Development: Volume III (Cancer Treatment and Anti-Infectives)
ISBN: 1632421380 ISBN-13(EAN): 9781632421388
Издательство: Неизвестно
Цена: 19955.00 р.
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Drug Discovery from Natural Products

Название: Drug Discovery from Natural Products
ISBN: 1849733619 ISBN-13(EAN): 9781849733618
Издательство: Royal Society of Chemistry
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Цена: 33790.00 р.
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Описание: An integrated review of the most recent trends in natural products drug discovery and key lead candidates that are outstanding for their chemistry and biology in novel drug development.

Natural Products as Antiviral Agents

Автор: C.K. Chu; H.G. Cutler
Название: Natural Products as Antiviral Agents
ISBN: 1461365090 ISBN-13(EAN): 9781461365099
Издательство: Springer
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Цена: 15672.00 р.
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Описание: During the past fifty years, thousands of natural products have been isolated from plants, fungi, and bacteria.


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