Basic and Applied Pharmacokinetics Self-Assessment, John E. Murphy
Автор: Hedaya, Mohsen A. Название: Basic Pharmacokinetics ISBN: 0367752158 ISBN-13(EAN): 9780367752156 Издательство: Taylor&Francis Рейтинг: Цена: 5511.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Bonate Название: Pharmacokinetics in Drug Development ISBN: 3319390511 ISBN-13(EAN): 9783319390512 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this volume, the specific challenges and problems facing the evaluation of new oncology agents are explored with regards to pharmacokinetic, pharmacodynamic modeling and clinical pharmacology development strategies. This book delivers, with an emphasis on the oncology therapeutic area, the goals set in the first three volumes: namely – to provide clinical pharmacologists practical insights for the application of pharmacology, pharmacokinetics and pharmacodynamics for new drug development strategies. Pharmacokinetic-pharmacodynamic concepts for tyrosine kinases, the evaluation of cardiac repolarization prolongation through QTc interval effects, efficacy- and safety-response analyses to support new drug approvals, clinical and preclinical tumor growth modeling, and flat- vs weight-based dose selection are showcased from an oncology clinical pharmacologist’s point-of-view. Oncology development strategies are surveyed for new FDA-approvals to identify patterns in expectations at time of first approval. The special considerations necessary to address combination drug development, metronomics, biosimilars and breakthrough therapies are also presented.
Автор: Wolfgang Название: HB of Basic Pharmacokinetics.2004 ISBN: 1582120544 ISBN-13(EAN): 9781582120546 Издательство: McGraw-Hill Рейтинг: Цена: 6004.00 р. Наличие на складе: Поставка под заказ.
Описание: The classic textbook of principles and techniques for practitioners, researchers, and undergraduate and graduate students involved in various applications of pharmacokinetics. Spanning 38 detailed chapters and an appendix providing pharmacokinetic data profiles on more than 420 drugs, this book includes information that is both current and accurate. Presented in a manner that fosters clinical application, readers will gain an understanding of the more precise equations for determining pharmacokinetic values.
Автор: Harald Sch?tz Название: Benzodiazepines II ISBN: 3642740332 ISBN-13(EAN): 9783642740336 Издательство: Springer Рейтинг: Цена: 19591.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The following considerations seem worth mentioning in connection with the preparation of Volume II: - To ensure continuity with Volume I as far as possible, the list of references was consecutively numbered (references 1 to 3779 in Volume I, references 3780 to 11338 in Volume II).
Автор: Jambhekar, Sunil S. Breen, Philip J. Название: Basic pharmacokinetics ISBN: 0853699801 ISBN-13(EAN): 9780853699804 Издательство: Pharmaceutical Press Рейтинг: Цена: 10692.00 р. Наличие на складе: Поставка под заказ.
Автор: Rosenbaum Sara E. Название: Basic Pharmacokinetics and Pharmacodynamics ISBN: 1119143152 ISBN-13(EAN): 9781119143154 Издательство: Wiley Рейтинг: Цена: 10922.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a comprehensive foundation for the contemporary application of pharmacokinetics and pharmacodynamics. The second edition updates and strengthens existing chapters and adds new topics to address current needs including physiologically based pharmacokinetic modeling, pharmacogenomics and predicting drug-drug interactions.
Автор: Bauer Название: Applied Clinical Pharmacokinetics ISBN: 0071794581 ISBN-13(EAN): 9780071794589 Издательство: McGraw-Hill Рейтинг: Цена: 12697.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Helps you learn the clinical application of pharmacokinetics. This book delivers clear and clinically relevant coverage of drug dosing and drug monitoring that no other text can match. It offers the standardized techniques and approaches to patient-specific dosing, and information on pharmacokinetically monitored drugs.
Описание: The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with empirical, compartmental, and stochastic pharmacokinetic models, and the fourth mainly with nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods. The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with empirical, compartmental, and stochastic pharmacokinetic models, and the fourth mainly with nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods. www.springeronline.com
Автор: Bauer, Larry A. Название: Applied clinical pharmacokinetics ISBN: 0071476288 ISBN-13(EAN): 9780071476287 Издательство: McGraw-Hill Рейтинг: Цена: 7720.00 р. Наличие на складе: Поставка под заказ.
Описание: Features coverage of drug dosing and monitoring. This book focuses on the standardized techniques and approaches to patient-specific dosing. It also contains sections on dosing strategies in the chapters and a chapter on sirolimus.
Автор: Shargel Название: Applied Biopharmaceutics & Pharmacokinetics ISBN: 0071240055 ISBN-13(EAN): 9780071240055 Издательство: McGraw-Hill Цена: 4288.00 р. Наличие на складе: Поставка под заказ.
Описание: The primary emphasis of this book is on the application and understanding of concepts. Basic theoretical discussions of the principles of biopharmaceutics and pharmacokinetics are provided, along with illustrative examples and practice problems and solutions to help the student gain skill in practical problem solving.
Описание: These volumes are designed to be the most complete guide to pharmacokinetics (PK) and its role in drug development. Geared toward graduate level students and scientists in the areas of clinical pharmacology and PK, the volumes will fill a gap between the academic science and the practical application of that knowledge in drug development. Volume 1 discusses the role that PK plays in selected clinical study designs, including first-time-in-man, biopharmaceuticals, and special population studies. Volume 2 details the key regulatory and development paradigms in which PK supplements decision-making during drug development.
Описание: These volumes are designed to be the most complete guide to pharmacokinetics (PK) and its role in drug development. Geared toward graduate level students and scientists in the areas of clinical pharmacology and PK, the volumes will fill a gap between the academic science and the practical application of that knowledge in drug development. Volume 1 discusses the role that PK plays in selected clinical study designs, including first-time-in-man, biopharmaceuticals, and special population studies. Volume 2 details the key regulatory and development paradigms in which PK supplements decision-making during drug development.
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