Clinical Applications of Mass Spectrometry in Drug Analysis: Methods and Protocols, Garg Uttam
Автор: Uttam Garg Название: Clinical Applications of Mass Spectrometry in Drug Analysis ISBN: 1493932519 ISBN-13(EAN): 9781493932511 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Clinical Applications of Mass Spectrometry in Drug Analysis
Автор: Reinhard Nie?ner, Andreas Sch?ffer Название: Organic Trace Analysis ISBN: 3110441144 ISBN-13(EAN): 9783110441147 Издательство: Walter de Gruyter Рейтинг: Цена: 11148.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
"Organic Trace Analysis" presents the basics of trace analysis, from sample preparation to the measurement: Students are introduced to statistical evaluation, quality control technologies, sampling and preparation of organic traces, as well as to enrichment and separation of samples. Spectroscopic techniques as chromatography, capillary electrophoresis, mass spectrometry, and receptor-based bioanalysis are presented in detail.
Описание: Exploring the methodologies and applications ofcomputational tools in drug design, this book is a practical introduction to chemoinformatics, molecular modelling and computational chemistry for researchers.
Автор: Joosten Heinz-Gerd, Golloch Alfred, Flock Jorg Название: Atomic Emission Spectrometry: AES - Spark, Arc, Laser Excitation ISBN: 3110527685 ISBN-13(EAN): 9783110527681 Издательство: Walter de Gruyter Цена: 18586.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Atomic Emission Spectrometry is a powerful analytical method which is utilized in academia and industry for quantitative and qualitative elemental analysis. This publication is an excellent guide to the technique, explaining the underlying theory and covering practical measurement applications. Extremely well-written and organized, this book is a beneficial instrument for every scientist or professional working with AES.
Автор: Zweigenbaum Jerry Название: Mass Spectrometry in Food Safety: Methods and Protocols ISBN: 1493957678 ISBN-13(EAN): 9781493957675 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: As a key component of human survival, a safe and sufficient food supply is essential for a healthy and productive population throughout the world, so assurance that the food supply is clean and free of harmful substances is a global concern. In Mass Spectrometry in Food Safety: Methods and Protocols, experts in the field provide context to the subject through reviews of regulations in various countries, the current state-of-the art, and specific, detailed scientific methods being employed today. The volume thoroughly covers the key areas in food safety, such as detection of low level chemical residues, pesticide analysis aided by chromatographic techniques, and the revealing of mycotoxins and chemical contaminants from packaging materials. Written in the highly successful Methods in Molecular Biology™ series format, method chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Pertinent and cutting-edge, Mass Spectrometry in Food Safety: Methods and Protocols serves researchers with both understanding and appreciation for the contribution of mass spectrometry and its vital application to food testing and food safety.
Описание: Serving as a practical handbook about ADMET for drug therapy, this book presents effective technologies, methods, applications, data interpretation, and decision-making tactics for pharmaceutical and preclinical scientists.
Автор: Langman Loralie J., Snozek Christine L. H. Название: LC-MS in Drug Analysis: Methods and Protocols ISBN: 1493961993 ISBN-13(EAN): 9781493961993 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Liquid-Chromatography-Mass-Spectrometry procedures have been shown to be successful when applied to drug development and analysis. LC-MS in Drug Analysis: Methods and Protocols provides detailed LC-MS/MS procedures for the analysis of several compounds of clinical significance. The first chapters provide the reader with an overview of mass spectroscopy, its place in clinical practice, its application of MS to TDM and toxicology, and the merits of LC-MS(/MS) and new sample preparation techniques. The following chapters discuss different approaches to screening for drugs of abuse and for general unknowns, as well as targeted measurement of specific analytes or classes of analytes including abused drugs, toxic compounds, and therapeutic agents. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, LC-MS in Drug Analysis: Methods and Protocols seeks to serve both professionals and novices with its well-honed methodologies.
Описание: In the last quarter century, advances in mass spectrometry (MS) have been at the forefront of efforts to map complex biological systems including the human metabolome, proteome, and microbiome. All of these developments have allowed MS to become a well-established molecular level technology for microorganism characterization. MS has demonstrated its considerable advantage as a rapid, accurate, and cost-effective method for microorganism identification, compared to conventional phenotypic techniques. In the last several years, applications of MS for microorganism characterization in research, clinical microbiology, counter-bioterrorism, food safety, and environmental monitoring have been documented in thousands of publications. Regulatory bodies in Europe, the US, and elsewhere have approved MS-based assays for infectious disease diagnostics. As of mid-2015, more than 3300 commercial MS systems for microorganism identification have been deployed worldwide in hospitals and clinical labs. While previous work has covered broader approaches in using MS to characterize microorganisms at the species level or above, this book focuses on strain-level and subtyping applications. In twelve individual chapters, innovators, leaders and practitioners in the field from around the world have contributed to a comprehensive overview of current and next-generation approaches for MS-based microbial characterization at the subspecies and strain levels. Chapters include up-to-date reference lists as well as web-links to databases, recommended software, and other useful tools. The emergence of new, antibiotic-resistant strains of human or animal pathogens is of extraordinary concern not only to the scientific and medical communities, but to the general public as well. Developments of novel MS-based assays for rapid identification of strains of antibiotic-resistant microorganisms are reviewed in the book as well. Microbiologists, bioanalytical scientists, infectious disease specialists, clinical laboratory and public health practitioners as well as researchers in universities, hospitals, government labs, and the pharmaceutical and biotechnology industries will find this book to be a timely and valuable resource.
Автор: Nair, Hari Название: Mass Spectrometry for the Clinical Laboratory ISBN: 0128008717 ISBN-13(EAN): 9780128008713 Издательство: Elsevier Science Рейтинг: Цена: 12462.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Mass Spectrometry for the Clinical Laboratory is an accessible guide to mass spectrometry and the development, validation, and implementation of the most common assays seen in clinical labs. It provides readers with practical examples for assay development, and experimental design for validation to meet CLIA requirements, appropriate interference testing, measuring, validation of ion suppression/matrix effects, and quality control. These tools offer guidance on what type of instrumentation is optimal for each assay, what options are available, and the pros and cons of each. Readers will find a full set of tools that are either directly related to the assay they want to adopt or for an analogous assay they could use as an example.
Written by expert users of the most common assays found in a clinical laboratory (clinical chemists, toxicologists, and clinical pathologists practicing mass spectrometry), the book lays out how experts in the field have chosen their mass spectrometers, purchased, installed, validated, and brought them on line for routine testing.
The early chapters of the book covers what the practitioners have learned from years of experience, the challenges they have faced, and their recommendations on how to build and validate assays to avoid problems. These chapters also include recommendations for maintaining continuity of quality in testing. The later parts of the book focuses on specific types of assays (therapeutic drugs, Vitamin D, hormones, etc.). Each chapter in this section has been written by an expert practitioner of an assay that is currently running in his or her clinical lab.
Автор: Avis Mark Название: Applications of Clinical Pharmacology in Drug Development ISBN: 1682861988 ISBN-13(EAN): 9781682861981 Издательство: Неизвестно Цена: 24138.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Clinical pharmacology plays a vital role in drug development to ascertain how the drug affects the human subject. The aim of this book is to discuss some essential researches and advancements in this field through concepts like drug toxicity, therapeutic drugs, clinical trials, pharmacokinetics, etc. In this book, using various studies and examples, constant effort has been made to make the understanding of the different applications of clinical pharmacology in drug development as easy and informative as possible, for the readers.
A visual guide for the interpretation of complex 1H-NMR spectra with a concise and illustrative practice problems section. This book is an easy-to-grasp source for (organic) chemists and students that want to understand and practice NMR spectroscopy.
Описание: * Greatly expanded and completely revised * Covers now not only drug application of biopharmaceuticals but also their use in diagnostics and vaccine development. * Includes material on quality control, safety issue, patent and legal regulations .
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