LC-MS in Drug Analysis: Methods and Protocols, Langman Loralie J., Snozek Christine L. H.
Автор: Zachariou Michael Название: Affinity Chromatography / Methods and Protocols ISBN: 1588296598 ISBN-13(EAN): 9781588296597 Издательство: Springer Рейтинг: Цена: 2000.00 р. Наличие на складе: Есть (2 шт.) Описание: Thirty-eight years after its introduction, affinity chromatography remains a key tool in th armory of separation techniques available to separation and interaction scientists. Expanded and updated from the first edition, this second edition volume aims to provide the beginner with the practical knowledge needed to develop affinity separations suitable for a variety of applications relevant to the post-genomic era.
Автор: Watson David G. Название: Pharmaceutical Analysis. 5 ed ISBN: 0702078077 ISBN-13(EAN): 9780702078071 Издательство: Elsevier Science Рейтинг: Цена: 5305.00 р. 7578.00-30% Наличие на складе: Есть (5 шт.) Описание: Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of analyses, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals. The mathematics involved is notoriously difficult, but this much-praised textbook, now revised and updated for its fifth edition, guides a student through the complexities with clear writing and the author's expertise from many years' teaching pharmacy students. Two new chapters have been added to the new edition covering methods used in the quality control of biotechnologically produced drugs, and electrochemical biosensors. There is continuous learning reinforcement throughout the book by way of worked calculation examples and self-assessment test questions. Worked calculation examples Self-assessment Additional problems (self tests) Practical boxes Key points boxes Two new chapters: Chapter 16 Methods used in the quality control of biotechnologically produced drugs Chapter 17 Electrochemical biosensors
Автор: Proetzel Gabriele, Wiles Michael V. Название: Mouse Models for Drug Discovery: Methods and Protocols ISBN: 1493981099 ISBN-13(EAN): 9781493981090 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With genetic engineering, systems explored in this book now exist allowing for the simple, efficient, and near universally precise genetic manipulation directly in any organism, including the mouse. Herein, these models are applied to a wide field of disease areas, including diabetes, cardiovascular disease, skin disorders, cancer, neurodegenerative and neuromuscular diseases, retinal disorders, as well as various behavioral models. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and fully updated, Mouse Models for Drug Discovery: Methods and Protocols, Second Edition serves to equip the reader with an extensive overview of techniques to utilize the many possibilities of mice in the drug development process.
Описание: The study of vaccine adjuvants has developed into an exciting area of work. In this authoritative and versatile book, expert researchers in the field provide clear and concise guidance on how to go about assessing the activity of adjuvant products.
Автор: Mavromoustakos Thomas, Tzakos Andreas G., Durdagi Serdar Название: Supramolecules in Drug Discovery and Drug Delivery: Methods and Protocols ISBN: 107160919X ISBN-13(EAN): 9781071609194 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This detailed book aims to provide readers with critical information to accomplish the synthesis of nanosystems for the purpose of supramolecular entities complexing with drugs, targeted drug delivery system characterization, as well as the study of the physical-chemical interactions that govern the stability and properties of these systems.
Описание: Providing an accessible introduction into the use of Total-Reflection X-ray Fluorescence (TXRF) Analysis, both from a theoretical point of view and for practical applications, this new edition of Total-Reflection X-Ray Fluorescence Analysis is completely updated and enlarged to emphasize new methods and techniques.
Автор: Smales C. Mark, James David C. Название: Therapeutic Proteins / Methods and Protocols ISBN: 1588293904 ISBN-13(EAN): 9781588293909 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: World-class researchers share their innovative and proven techniques for the production of therapeutic proteins downstream of the discovery stage. The methods use a variety of sources for producing therapeutic proteins, including bacterial and yeast expression systems, and insect and mammalian cells, and then cover the purification of the resulting protein using both state-of-the-art and traditional methods, such as those sourced from plasma. Additional chapters offer methods for the characterization of therapeutic proteins throughout the production process, along with methods and strategies for viral inactivation and protein formulation. The protocols follow the successful Methods in Molecular Biologyв„ў series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
Автор: Carr Daniel J. J. Название: Interferon Methods and Protocols ISBN: 1588294188 ISBN-13(EAN): 9781588294180 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A compendium of methods to measure type I interferon efficacy as an antiproliferative or an antiviral agent. This book offers researchers tools not only to ascertain the functions of IFN-stimulatory gene products, but also to identify additional molecular pathways that will clarify our understanding of various biological events influenced by IFNs.
1. Mass Spectrometry in Clinical Laboratory: Applications in Therapeutic Drug Monitoring and Toxicology Uttam Garg and Yan Victoria Zhang
2. Quantitation of Flecainide, Mexiletine, Propafenone, and Amiodarone in Serum or Plasma Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Matthew H. Slawson and Kamisha L. Johnson-Davis 3. Quantitation of the Oral Anticoagulants Dabigatran, Rivaroxaban, Apixaban, and Warfarin in Plasma Using Ultra-Performance Liquid Chromatography with Tandem Mass Spectrometry (UPLC-MS/MS) Jaime H. Noguez and James C. Ritchie 4. Simultaneous Quantitation of Lamotrigine, Levetiracetam, 10-Hydroxycarbazepine, Topiramate, and Zonisamide in Serum Using HPLC-MS/MS Dean C. Carlow, Heng Shi, and Ryan C. Schofield 5. Quantification of the Triazole Antifungal Compounds Voriconazole and Posaconazole in Human Serum or Plasma Using Liquid Chromatography Electrospray Tandem Mass Spectrometry (HPLC-ESI-MS/MS) Alejandro R. Molinelli and Charles H. Rose, IV 6. Quantitation of Haloperidol, Fluphenazine, Perphenazine, and Thiothixene in Serum or Plasma Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Matthew H. Slawson and Kamisha L. Johnson-Davis 7. Quantitation of Total Buprenorphine and Norbuprenorphine in Meconium by LC-MS/MS Stephanie J. Marin and Gwendolyn A. McMillin 8. Quantitation of Buprenorphine, Norbuprenorphine, Buprenorphine Glucuronide, Norbuprenorphine Glucuronide, and Naloxone in Urine by LC-MS/MS Stephanie J. Marin and Gwendolyn A. McMillin 9. A Simple Liquid Chromatography Tandem Mass Spectrometry Method for Quantification of Plasma Busulfan Shuang Deng, Michael Kiscoan, Clint Frazee, Susan Abdel-Rahman, Jignesh Dalal, and Uttam Garg 10. High-Throughput Quantitation of Busulfan in Plasma Using Ultra-Fast Solid Phase Extraction Tandem Mass Spectrometry (SPE-MS/MS) Loralie J. Langman, Darlington Danso, Enger Robert, and Paul J. Jannetto 11. Quantification of 11-Carboxy-Delta-9-Tetrahydrocannbinol (THC-COOH) in Meconium Using Gas Chromatography Mass Spectrometry (GC/MS) Judy Peat, Brehon Davis, Clint Frazee, and Uttam Garg 12. Quantitation of Carisoprodol and Meprobamate in Urine and Plasma Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Matthew H. Slawson and Kamisha L. Johnson-Davis 13. Cetirizine Quantification by High Performance Liquid Chromatography Tandem Mass Spectrometry (LC/MS/MS) Ada Munar, Clint Frazee, Bridgette Jones, and Uttam Garg 14. Quantification of Docetaxel in Serum Using Turbulent Flow Liquid Chromatography Electrospray Tandem Mass Spectrometry (TFC-HPLC-ESI-MS/MS) Christopher A. Crutchfield, Mark A. Marzinke and William Clarke 15. Comprehensive Urine Drug Screen by Gas-Chromatography Mass Spectrometry (GC/MS) Bheemraj Ramoo, Melissa Funke, Clint Frazee, and Uttam Garg 16. Broad Spectrum Drug Screening Using Liquid Chromatography-Hybrid Triple Quadrupole Linear Ion Trap Mass Spectrometry Judy Stone 17. High Resolution Mass Spectrometry for Untargeted Drug Screening Alan H.B. Wu and Jennifer Colby 18. Quantitation of Ethyl Glucuronide and Ethyl Sulfate in Urine Using Liquid Chromatography-Tandem Mass Spectrometry(LC-MS/MS) Matthew H. Slawson and Kamisha L. Johnson-Davis 19. Quantification of Hydroxychloroquine in Blood Using Turbulent Flow Liquid Chromatography-Tandem mass Soectrometry (TFLC-MS/MS) Allison B. Chambliss, Anna K. Fьzйry, and William A. Clarke 20. Quantification of Iohexol in Serum by High Performance Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) Faye B. Vicente, Gina Vespa, Alan Miller, and Shannon Haymond 21. Quantitation of Teriflunomide in Human Serum/Plasma Across a 4
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