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Cancer Susceptibility: Methods and Protocols, Webb Michelle


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Автор: Webb Michelle
Название:  Cancer Susceptibility: Methods and Protocols
ISBN: 9781493957606
Издательство: Springer
Классификация:

ISBN-10: 1493957600
Обложка/Формат: Paperback
Страницы: 295
Вес: 0.54 кг.
Дата издания: 23.08.2016
Серия: Methods in molecular biology
Язык: English
Издание: Softcover reprint of
Иллюстрации: 20 tables, black and white; xi, 295 p.
Размер: 25.40 x 17.78 x 1.65 cm
Читательская аудитория: General (us: trade)
Подзаголовок: Methods and protocols
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание: Over the past two decades, spectacular advances have been made in our understanding of the molecular genetics of cancer, leading to the pursuit of identifying genes that, when mutated, result in an increased susceptibility to the disease. In Cancer Susceptibility: Methods and Protocols, experts in the field bring together the most recent technological developments for identifying and screening cancer susceptibility genes. Divided into two clear sections, the book begins with gene identification, which updates and informs scientists working at identifying novel cancer susceptibility genes, while the second part deals with mutation screening technologies that aid scientists and clinicians working to translate this knowledge into the clinic. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cancer Susceptibility: Methods and Protocols is a timely collection that seeks to provide researchers with the tools to predict and combat this terrible disease.
Дополнительное описание: Identifying Cancer Susceptibility Genes.- The Identification of Colon Cancer Susceptibility Genes by Using Genome-Wide Scans.- Prioritizing Candidate Genetic Modifiers of BRCA1 and BRCA2 Using a Combinatorial Analysis of Global Expression and Polymorphism



In Situ Detection of DNA Damage / Methods and Protocols

Автор: Didenko Vladimir V.
Название: In Situ Detection of DNA Damage / Methods and Protocols
ISBN: 0896039528 ISBN-13(EAN): 9780896039520
Издательство: Springer
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Цена: 5809.00 р.
Наличие на складе: Есть (4 шт.)
Описание: In In Situ Detection of DNA Damage: Methods and Protocols, Vladimir Didenko and a panel of experts describe all the major in situ techniques for studying DNA damage and apoptosis, and how approaches originally designed to label apoptotic cells can be used for DNA damage analysis (and vice versa). The readily reproducible techniques presented here include all those designed to detect specific single- and double-stranded DNA breaks in tissue sections while using polymerases, ligases, nucleases, and kinases. There are also novel instrumental techniques that use ultrasound for in vivo and in situ detection of apoptotic DNA damage, and in situ applications of flow and laser-scanning cytometry for analysis of DNA strand breaks and apoptosis. State-of-the-art and highly practical, In Situ Detection of DNA Damage: Methods and Protocols presents for the first time a complete set of enzymatic methods for determining DNA breaks, and will greatly facilitate the work of all those studying the in situ detection of DNA damage and the labeling of apoptotic cells.

Affinity Chromatography / Methods and Protocols

Автор: Zachariou Michael
Название: Affinity Chromatography / Methods and Protocols
ISBN: 1588296598 ISBN-13(EAN): 9781588296597
Издательство: Springer
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Цена: 2000.00 р.
Наличие на складе: Есть (2 шт.)
Описание: Thirty-eight years after its introduction, affinity chromatography remains a key tool in th armory of separation techniques available to separation and interaction scientists.  Expanded and updated from the first edition, this second edition volume aims to provide the beginner with the practical knowledge needed to develop affinity separations suitable for a variety of applications relevant to the post-genomic era.

Genetic Susceptibility to Cancer

Автор: Seymour Garte
Название: Genetic Susceptibility to Cancer
ISBN: 0792383834 ISBN-13(EAN): 9780792383833
Издательство: Springer
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Цена: 27951.00 р.
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Описание: Recent research has discovered that for many of these `sporadic` (non-familial) cancer cases, defects or aberrations in certain metabolic genes not previously associated with genetic cancer risk may contribute to either causing the disease or at least increasing the chances of developing cancer.

Genetic Susceptibility to Cancer

Автор: Seymour Garte
Название: Genetic Susceptibility to Cancer
ISBN: 1461372658 ISBN-13(EAN): 9781461372653
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Recent research has discovered that for many of these `sporadic` (non-familial) cancer cases, defects or aberrations in certain metabolic genes not previously associated with genetic cancer risk may contribute to either causing the disease or at least increasing the chances of developing cancer.

Standardization of Epidemiologic Studies of Host Susceptibility

Автор: Janice S. Dorman
Название: Standardization of Epidemiologic Studies of Host Susceptibility
ISBN: 1489912150 ISBN-13(EAN): 9781489912152
Издательство: Springer
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Цена: 20962.00 р.
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Описание: Proceedings of a NATO ARW held in Pittsburgh, Pennsylvania, June 23-27, 1992.

Cancer Gene Profiling: Methods and Protocols

Автор: Grutzmann Robert, Pilarsky Christian
Название: Cancer Gene Profiling: Methods and Protocols
ISBN: 1493979973 ISBN-13(EAN): 9781493979974
Издательство: Springer
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Цена: 15998.00 р.
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Описание:

1. Factors Affecting the Use of Human Tissues in Biomedical Research: Implications in the Design and Operation of a Biorepository
Daniel S. Atherton, Katherine C. Sexton, Dennis Otali, Walter C. Bell, and William E. Grizzle

2. Tissue Microdissection
Anja Rabien and Glen Kristiansen

3. Tissue Microarrays
Ana-Maria Dancau, Ronald Simon, Martina Mirlacher, and Guido Sauter

4. Gene Expression Analysis in the Age of Mass Sequencing: An Introduction
Christian Pilarsky, Lahiri Kanth Nanduri, and Janine Roy

5. Quantitative DNA Methylation in Cancer
Ole Ammerpohl, Andrea Haake, Julia Kolarova, and Reiner Siebert

6. Single Nucleotide Polymorphism to Associate Cancer Risk
Victoria Shaw, Katie Bullock, and William Greenhalf

7: Exosomes in Cancer Disease
Margot Zцller

8: MicroRNAs (miRNAs) Profiling
Lu Gao and Feng Jiang

9. Cancer Gene Profiling for Response Prediction
B. Michael Ghadimi and Peter Jo

10. Target Gene Discovery for Novel Therapeutic Agents in Cancer Treatment
Sanjay Tiwari, Ole Ammerpohl, and Holger Kalthoff

11. Application of Proteomics in Cancer Biomarker Discovery: GeLC-MS/MS
Pedro R. Cutillas and Tatjana Crnogorac-Jurcevic

12. Meta-Analysis of Cancer Gene Profiling Data
Janine Roy, Christof Winter, and Michael Schroeder

13. Reproducible, Scalable Fusion Gene Detection from RNA-Seq
Vladan Arsenijevic and Brandi N. Davis-Dusenbery

14. Transcriptome Sequencing for the Detection of Chimeric Transcripts
Hsueh-Ting Chu

Bioinformatics for Cancer Immunotherapy: Methods and Protocols

Автор: Boegel Sebastian
Название: Bioinformatics for Cancer Immunotherapy: Methods and Protocols
ISBN: 1071603264 ISBN-13(EAN): 9781071603260
Издательство: Springer
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Цена: 16769.00 р.
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Описание: This volume focuses on a variety of in silico protocols of the latest bioinformatics tools and computational pipelines developed for neo-antigen identification and immune cell analysis from high-throughput sequencing data for cancer immunotherapy.


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