Cancer Gene Profiling: Methods and Protocols, Grutzmann Robert, Pilarsky Christian

Автор: Rani Sweta
Название: Microrna Profiling: Methods and Protocols
ISBN: 1493982257 ISBN-13(EAN): 9781493982257
Издательство: Springer
Рейтинг:
Цена: 13974.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: "Published In: United States, 07 December 2016 " --Distributor`s website.

Автор: Simone Mocellin
Название: Microarray Technology and Cancer Gene Profiling
ISBN: 1441922989 ISBN-13(EAN): 9781441922984
Издательство: Springer
Рейтинг:
Цена: 27951.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Given the revolutionary implications that the use of this technology might have in the clinical management of cancer patients, the principles of DNA array-based tumor gene profiling must be clearly understood for the data to be correctly interpreted and appreciated.

Автор: Binnig, Gerd Huss, Ralf Schmidt, Gunter
Название: Tissue phenomics: profiling cancer patients for treatment decisions
ISBN: 981477488X ISBN-13(EAN): 9789814774888
Издательство: Taylor&Francis
Рейтинг:
Цена: 21284.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: In the age of digitization our society is transformed into a new state. In particular, machine intelligence dramatically elevates our capability to create and digest information. Naturally, healthcare is also impacted by this trend and will even be more transformed into a informatic driven discipline in the future. In the most important area of histo-pathology, the interpretation of tissue slices from cancer patients, informatics will have an early and huge impact on treatment decisions and probably will act as the leading discipline for this transformation in medicine. Tissue Phenomics provides a comprehensive methodology aiming at the discovery of the most accurate tissue-based decision support algorithm by close integration of assay development, image analysis and bioinformatics, and optimization feedback loops. In this book the methodology of Tissue Phenomics and its benefits and wealth’s are described. The different components of Tissue Phenomics are explained in the different chapters. In the chapters 2 to 4 of this book different authors describe various approaches on how to convert the wealth of tissue slide pixel data into mineable information using knowledge-based and data-driven image analysis methods. Subsequently, the datafication of images and the bioinformatics part plays a crucial role in generating prognostic and predictive models for disease progression. The integration of other data sources such as genomics, radiomics and patient related information is also important and is described as well. As discussed in chapters 5 and 6, these models may classify patients in distinct groups such as those responding to a given therapy. Since Tissue Phenomics provides a huge set of potentially prognostic features (phenes), one focus of both chapters is robust feature selection methods by advanced Monte-Carlo cross validation algorithms. In chapter 7 we discuss multiple application examples of Tissue Phenomics in academic and commercial settings and its tremendous impact to advances in biomedical sciences. Building on the successes in research, chapters 8 and 9 discuss applications in clinical environments and provide a flavor to the future envision in chapter 10, where tissue datafication and subsequent patient profiling is part of every routine examination, with the goal to best match patients with the most successful therapy, as predicted by tissue phenes.

Автор: Robert Gr?tzmann; Christian Pilarsky
Название: Cancer Gene Profiling
ISBN: 1493932039 ISBN-13(EAN): 9781493932030
Издательство: Springer
Рейтинг:
Цена: 19564.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Cancer Gene Profiling

Автор: Lorraine O`Driscoll
Название: Gene Expression Profiling
ISBN: 149396173X ISBN-13(EAN): 9781493961733
Издательство: Springer
Рейтинг:
Цена: 16769.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: In this book, experts present a broad range of available and developing techniques for the analysis of gene expression at the DNA, RNA, and protein levels. A collection of clearly described and illustrated chapters includes tips and implementation advice.

Автор: Sarah S. Murray
Название: Tumor Profiling
ISBN: 1493990020 ISBN-13(EAN): 9781493990023
Издательство: Springer
Рейтинг:
Цена: 13974.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book provides a practical guide to current methods for profiling and interpreting genomic alterations in tumors. Chapters detail methods to interrogate DNA variation, RNA expression, and epigenetic changes using both next-generation sequencing and microarray techniques, common bioinformatics and annotation tools to glean relevant driver genomic events, and different performance characteristics as well as quality metrics necessary for the robust validation of tumor profiling as a diagnostic test for medical laboratories. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Tumor Profiling: Methods and Protocols aims to be a useful resource for learning about technical details, applications, and strengths and limitations of the latest technologies as applied to this increasingly important field.

Автор: Jian-Bing Fan
Название: Next-Generation MicroRNA Expression Profiling Technology
ISBN: 1493962175 ISBN-13(EAN): 9781493962174
Издательство: Springer
Рейтинг:
Цена: 20263.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: The rapid pace of research in this field continues to drive technical advances that make methods more sensitive and applicable. This volume features many new methodologies described by leading researchers, including reproducible laboratory protocols.

Автор: Rani
Название: MicroRNA Profiling
ISBN: 1493965220 ISBN-13(EAN): 9781493965229
Издательство: Springer
Рейтинг:
Цена: 18167.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This volume includes comprehensive descriptions of miRNA biogenesis and their role in the development and progression of various human diseases. The first few chapters of MicroRNA Profiling: Methods and Protocols discuss the effects of over-expressing and repressing of a target miRNA and their effects on cell viability and proliferation. The next few chapters explore the protocols for total RNA isolation from cells and cell-derived product including formalin fixed paraffin embedded tissue and plant tissue. The last few chapters discuss isolation and characterization of exosomes from medium conditioned by cell lines, serum, and plasma specimens. This book also includes discussions of several software tools, such as miRandola, PicTar, DIANA, and miRWalk. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and cutting-edge, MicroRNA Profiling: Methods and Protocols is a valuable resource for anyone interested in the field of Micro RNAs.

Автор: J?rg Epplen; Thomas Lubjuhnn
Название: DNA Profiling and DNA Fingerprinting
ISBN: 3764360186 ISBN-13(EAN): 9783764360184
Издательство: Springer
Рейтинг:
Цена: 13060.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This text reflects practical approaches to answering a variety of biological and medical questions, using DNA fingerprinting and genetic profiling in a broad sense that also includes statistical evaluation of the data. The book is aimed at students as well as academic teachers and researchers.