Notch Signaling in Embryology and Cancer: Molecular Biology of Notch Signaling, Reichrath Jцrg, Reichrath Sandra
Автор: Gary C. Schoenwolf et al. Название: Larsen`s Human Embryology, 6e ISBN: 032369604X ISBN-13(EAN): 9780323696043 Издательство: Elsevier Science Рейтинг: Цена: 11115.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Offering a well-organized, straightforward approach to a highly complex subject, Larsen's Human Embryology, 6th Edition, provides easy-to-read, comprehensive coverage of human embryonic development for today's students. It integrates anatomy and histology with cellular and molecular mechanisms, focusing on both normal development and congenital anomalies. Highly illustrated with superb drawings and photographs, it features a strong clinical focus based on the most up-to-date scientific discoveries and understanding.Contains new information on gene editing via CRISPr technology, organoids and the study of human disease, transcription factors and signaling pathways, and single cell sequencing.
Includes clinical scenarios that describe prevention, diagnosis, and treatment of human birth defects and disease. Features a superior art program, online animations, and high-quality drawings and photographs throughout-ideal for today's visual learners. * Includes a strong clinical emphasis through the use of Clinical Tasters, Embryology in Practice, and In the Clinic sections.
Provides additional information on mechanisms of development and research approaches and strategies to establish these mechanisms with In the Research Lab sections. Begins each chapter with an overview of main points as well as a graphical summary, with key terms listed in bold type. Covers the embryology information that today's medical students need to know for Board exams, clinics, and more, in a readable, straightforward manner.
Enhanced eBook version included with purchase. Your enhanced eBook allows you to access 50 narrated animations, multiple-choice questions, and all of the text, figures, and references from the book on a variety of devices.
Автор: Sadler Thomas Название: Langman`s Medical Embryology, International Edition 13e ISBN: 1469897806 ISBN-13(EAN): 9781469897806 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 5577.00 р. Наличие на складе: Поставка под заказ.
Описание: Offering exceptional full color diagrams and clinical images, Langman's Medical Embryology, 13e helps medical, nursing, and health professions students develop a basic understanding of embryology and its clinical relevance. Concise chapter summaries, captivating clinical correlates boxes, clinical problems, and a clear, concise writing style make the subject matter accessible to students and relevant to instructors. The new edition is enhanced by over 100 new and updated illustrations, additional clinical images and photos of early embryologic development, and an expanded chapter on the cardiovascular system. In addition, online teaching and learning resources include the fully searchable text online, as well as an interactive Quiz Bank for students and an image bank.Clinical Correlates boxes illustrated by cases and images cover birth defects, developmental abnormalities, and other clinical phenomena.More than 400 illustrations—including full-color line drawings, scanning electron micrographs, and clinical images—clarify key aspects of embryonic development.Basic genetic molecular biology principles are highlighted throughout the text to link embryology to other critical specialties.Chapter Overview figures provide a visually compelling introduction to each chapter.Problems to Solve (with detailed answers at the back of the book) help you assess your understanding.An expanded glossary defines key terms and concepts.An online interactive USMLE-style Question Bank helps you review for exams and prepare for the Boards.
Автор: Sadler, Dr. T.W., PhD Название: Langman`s Medical Embryology, 14e. ISBN: 1975114841 ISBN-13(EAN): 9781975114848 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 9146.00 р. Наличие на складе: Поставка под заказ.
Описание: Vibrantly illustrated with full-color diagrams and clinical images, Langman's Medical Embryology , 14th Edition helps medical, nursing, and health professions students confidently develop a basic understanding of embryology and its clinical relevance. Concise chapter summaries, captivating clinical correlates boxes, clinical problems, and a clear, concise writing style make the subject matter accessible and engaging to students throughout their courses. Updated content reflects the latest clinical findings on the effects of the Zika virus, urogenital system disorders, and more.
Clinical Correlates boxes tie clinically relevant content to case-based scenarios students may encounter in practice. More than 400 full-color illustrations, micrographs, and clinical images clarify key aspects of embryonic development. Problems to Solve with accompanying answers help assess student understanding.
Chapter summaries and an expanded glossary reinforce understanding of key development stages, terms, and clinical conditions. Illustrated Development Chart visually guides students through the stages of embryonic development at a glance. eBook available for purchase.
Fast, smart, and convenient, today's eBooks can transform learning. These interactive, fully searchable tools offer 24/7 access on multiple devices, the ability to highlight and share notes, and more
Автор: Yagel Название: Fetal Cardiology: Embryology, Genetics, Physiology, Echocardiography Evaluation, Diagnosis and Perinatal Management of Cardiac Diseases ISBN: 0415432650 ISBN-13(EAN): 9780415432658 Издательство: Taylor&Francis Рейтинг: Цена: 14015.00 р. Наличие на складе: Есть (2 шт.) Описание: Logic and Reality is a collection of essays by philosophers, logicians, mathematicians, and computer scientists, celebrating the work of the distinguished philosopher Arthur Prior. Topics range from philosophical discussions of the nature of time and of the nature of logic iteself, to descriptions of computer systems that can reason and take account of the fact that they exist in a temporal world.
Автор: Barry K.B Berkovitz, G. R. Holland, Bernard J. Moxham Название: Oral Anatomy, Histology and Embryology. 5 ed. IE ISBN: 0723438137 ISBN-13(EAN): 9780723438137 Издательство: Elsevier Science Рейтинг: Цена: 6631.00 р. Наличие на складе: Поставка под заказ.
Описание:
Now entering its 40th anniversary, the fifth edition of Oral Anatomy, Histology and Embryology has been thoroughly overhauled, updated and augmented to meet the needs of dental students worldwide. Now available with new pedagogic features and an enhanced illustration program, Oral Anatomy, Histology and Embryology 5th edition also comes with a free online program containing a wide selection of MCQs and additional learning exercises to allow readers to test and reinforce their knowledge.
Автор: Singh Название: Textbook of Clinical Embryology, 2e ISBN: 8131248828 ISBN-13(EAN): 9788131248829 Издательство: Elsevier India Рейтинг: Цена: 1525.00 р. Наличие на складе: Есть (3 шт.)
Описание: This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer.
Автор: Ronald W. Dudek Название: BRS; Embryology. 6 ED ISBN: 1451190387 ISBN-13(EAN): 9781451190380 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 6862.00 р. Наличие на складе: Поставка под заказ.
Описание: Succeed on the USMLE, other board exams, and course exams with this updated Sixth Edition of BRS Embryology. Acclaimed for its easy-to-read, easy-to-scan outline format, this bestselling book includes over 220 USMLE-style questions with complete answers and explanations, as well as exams at the end of each chapter and an end-of-book Comprehensive Examination. Enhanced by outstanding radiographs, sonograms, computed tomography scans, and clinical photographs of various congenital malformations, this proven book covers the facts and concepts tested on the USMLE within the context of human embryologic development. Offered in both print and online formats, the book boosts confidence and provides maximum accessibility and portability for in-class or on-the-go learning. Maximize study time with the Board Review Series quick scan outline format. Prepare for the board exam with more than 220 USMLE-style questions and answers. Focus your board review prep using the icons that highlight the information key to the USMLE exam. See the connection between human embryologic knowledge and clinical medicine through Clinical Considerations sections. Master key facts and information with illustrations and tables that summarize information for convenient review. Practice for the board examination using the comprehensive end-of-book exam. Enhance your visual understanding with high quality radiographic/ diagnostic and clinical images that clarify key facts and conceptsFind key information fast with anytime, anywhere access to the fully searchable text on the free companion website, which also features interactive quizzing.
1. Notch signaling in prevention ant therapy: fighting cancer with a two-sided sword
2. Transcription factor RBPJ as a molecular switch in regulating the Notch response
3. Unraveling of Hidden Secrets: The tumour suppressor Lethal (2) giant discs (Lgd)/CC2D1, Notch Signaling and Cancer
4. Notch and endometrial cancer
5. Notch and Esophageal Squamous Cell Carcinoma
6. Notch signaling and liver cancer
7. Notch inHead and Neck Cancer
8. Notch Signaling and Human Papillomavirus-Associated Oral Tumorigenesis
9. The impact of Notch signalingfor carcinogenesis and progression of non-melanoma skin cancer: lessons learned fromcancer stem cells, tumor angiogenesis, and beyond
10. Notch Signaling in Thyroid Cancer
11. The Relevance of Notch Signaling in Cancer Progression
12. Notch Signaling and the Breast Cancer Microenvironment
13. Notch pathway: a journey from notching phenotypes to cancer immunotherapy
Index
Автор: Tilman Borggrefe; Benedetto Daniele Giaimo Название: Molecular Mechanisms of Notch Signaling ISBN: 3030077896 ISBN-13(EAN): 9783030077891 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Поставка под заказ.
Описание: This book describes the Notch signaling pathway with a focus on molecular mechanisms. The Notch signaling pathway is a seemingly simple pathway that does not involve any second messenger. Upon ligand binding two consecutive proteolytic cleavages of the NOTCH receptor release the Notch intracellular domain from the membrane. The Notch intracellular domain migrates into the nucleus and activates gene expression. Recently, new technologies allowed us to better understand this pivotal signaling cascade and revealed new regulatory mechanisms. The different chapters cover many aspects of the Notch signaling focusing on the mechanisms governing the receptor/ligand interaction as well as on the downstream intracellular signaling events. Aspects of both canonical and non-canonical signaling are discussed and the function of Notch signaling in physiological and pathological contexts are elucidated. This book is not only intended for experts but it should also be a useful resource for young, sprouting scientists or interested scientists from other research areas, who may use this book as a stimulating starting point for further discoveries and developments.
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