Synthetic Antibodies: Methods and Protocols, Tiller Thomas
Автор: Steinitz Michael Название: Human Monoclonal Antibodies: Methods and Protocols ISBN: 149398957X ISBN-13(EAN): 9781493989577 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This second edition volume expands on the previous edition with descriptions of recent developments in the field. The chapters in this book cover topics such as monoclonal antibodies for the treatment of melanoma; production and purification of human monoclonal antibodies; humanization and optimization of monoclonal antibodies; rapid chimerization of monoclonal antibodies; epitope mapping via phage display from single gene libraries; recombinant antibodies made by combining phage and yeast display selections; production of stabilized antibody fragments in the E. coli bacterial cytoplasm and transfected mammalian cells; and analysis of CAR T cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Unique and thorough, Human Monoclonal Antibodies: Methods and Protocols, Second Edition is a valuable tool for novice and expert researchers interested in learning more about this evolving field.
Автор: Albitar Maher Название: Monoclonal antibodies / methods and protocols ISBN: 1588295672 ISBN-13(EAN): 9781588295675 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Поставка под заказ.
Описание: Monoclonal Antibodies: Methods and Protocols examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting with opening chapters focusing on the gold standard method for generating mouse monoclonal antibodies through hybridoma technology, future methods for engineering recombinant and humanized antibodies, methods for engineering soluble Fc fusion protein, and the use of antibodies and flow cytometry in the quantification of cell signaling proteins. Specific chapters describe how antibodies are used for the diagnosis and classification of hematologic diseases. Subsequent chapters examine the advantages and most recent advances of using bead-based immunoassays, including the ability of bead-based technology to multiplex and analyze several analytes simultaneously, and the use of beads in detecting fusion proteins resulting from chromosomal translocations. Concluding chapters provide additional examples of methodologies that employ monoclonal antibodies.Monoclonal Antibodies: Methods and Protocols provides descriptions of methods that cover a wide spectrum of applications in the field of monoclonal antibodies. This field will continue to expand and provide new and innovative techniques, not only in the laboratory, but also as a basis that complements targeted therapy.
Автор: Michael Steinitz (Editor) Название: Human Monoclonal Antibodies: Methods and Protocols ISBN: 1627035850 ISBN-13(EAN): 9781627035859 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book details readily reproducible protocols of cellular and molecular methods for the production, purification and application of human monoclonal antibodies. It also includes articles on related topics of human monoclonal and polyclonal antibodies.
Автор: Thomas Tiller Название: Synthetic Antibodies ISBN: 1493968556 ISBN-13(EAN): 9781493968558 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This detailed volume presents a set of protocols useful for researchers in the field of recombinant immunoglobulin and alternative scaffold engineering, aptamer development, and generation of molecularly imprinted polymers (MIPs).
Автор: R. Gieseler; Johann H. Peters; G. K?hler; P. Debba Название: Monoclonal Antibodies ISBN: 3642745342 ISBN-13(EAN): 9783642745348 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous authors
Автор: Hans U. Lutz Название: Naturally Occurring Antibodies (NAbs) ISBN: 1493953311 ISBN-13(EAN): 9781493953318 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Here, pioneering researchers report on the tissue homeostatic, tissue regenerating and regulatory properties of NAbs and NAbs in pooled human IgG. The volume also has a chapter on the history of how pooled plasma was pretreated for safe intravenous use.
Автор: Juan J. Lafaille; Maria A. Curotto de Lafaille Название: IgE Antibodies: Generation and Function ISBN: 3319137247 ISBN-13(EAN): 9783319137247 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites. It highlights the unique mechanisms involved in the regulation of IgE production at both the molecular and cellular level. Furthermore, it discusses in detail novel findings on how the affinity, specificity and cross-reactivity of IgE can fine-tune mast cell responses to allergens. The book also explores the beneficial roles of IgE antibodies in immunity to helminthes and protection against tumors, and how the properties of IgE-mediated immunity are employed in the development of IgE therapeutic antibodies. All chapters were written by respected experts in their fields and will appeal to scientists and clinicians alike.
Автор: Vincent Ossipow; Nicolas Fischer Название: Monoclonal Antibodies ISBN: 1627039910 ISBN-13(EAN): 9781627039918 Издательство: Springer Рейтинг: Цена: 32142.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Part I covers monoclonal antibody generation, Part II deals with monoclonal antibody expression and purification, Part III presents methods for monoclonal antibody characterization and modification, and Part IV describes selected applications of monoclonal antibodies.
Автор: Kaveri Srinivas V., Bayry Jagadeesh Название: Natural Antibodies: Methods and Protocols ISBN: 1493984098 ISBN-13(EAN): 9781493984091 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Поставка под заказ.
Описание: This volume looks at the role of natural antibodies in pathogen elimination, cell survival, inflammation, cancer, and autoimmunity.
Автор: Benjamin Bonavida Название: Resistance to Immunotherapeutic Antibodies in Cancer ISBN: 1489987320 ISBN-13(EAN): 9781489987327 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book examines antibody-mediated anti-cancer therapy, covering the use of mAbs against various cancers, developments in the molecular, biochemical and genetic mechanisms of resistance by various mAbs and novel mAbs to overcome drug and radition resistance.
Автор: Kresina Название: Monoclonal Antibodies ISBN: 0824781163 ISBN-13(EAN): 9780824781163 Издательство: Taylor&Francis Рейтинг: Цена: 49764.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Presents a sampling of new and novel approaches to the amelioration of musculoskeletal disease pathology, emphasizing prevention and therapy. Where applicable, these new technologies are focused on their application to human autoimmune diseases, but the volume mainly discusses and details the use of
Автор: Gunnar Houen Название: Peptide Antibodies ISBN: 1493949993 ISBN-13(EAN): 9781493949991 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: For example, peptide antibodies which are dependent on specific posttranslational modifications are of great interest, such as phosphorylation, citrullination and others, while different forms of recombinant peptide antibodies are gaining interest, notably nanobodies, single chain antibodies, TCR-like antibodies, among others.
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