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The Myc Gene: Methods and Protocols, Soucek Laura, Whitfield Jonathan


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Автор: Soucek Laura, Whitfield Jonathan
Название:  The Myc Gene: Methods and Protocols
ISBN: 9781071614754
Издательство: Springer
Классификация:
ISBN-10: 1071614754
Обложка/Формат: Hardcover
Страницы: 349
Вес: 0.82 кг.
Дата издания: 22.06.2021
Язык: English
Размер: 25.91 x 19.81 x 2.29 cm
Ссылка на Издательство: Link
Поставляется из: Германии
Описание: 1. An -omycs Toolbox to Work with MYC

Jonathan R. Whitfield and Laura Soucek

2. Methods of Expression, Purification and Preparation of the c-Myc b-HLH-LZ for its Biophysical Characterization Patrick Delattre, Martin Montagne, and Pierre Lavigne

3. Biophysical and Structural Methods to Study the bHLHzip Region of Human c-MYC

Giovanna Zinzalla

4. Identifying and Validating MYC: protein Interactors in Pursuit of Novel anti-MYC Therapies

Diana Resetca, Alannah S. MacDonald, Tristan M. G. Kenney, Yong Wei, Cheryl H. Arrowsmith, Brian Raught, and Linda Z. Penn

5. Detection of Post-Translational Modifications on MYC

Colin J. Daniel, Xiao-Xin Sun, Yingxiao Chen, Xiaoli Zhang, Mu-Shui Dai, and Rosalie C. Sears

6. MYC Analysis in Cancer and Evolution

Markus Hartl and Klaus Bister

7. Genome-wide analysis of c-MYC-regulated mRNAs and miRNAs, and c-MYC DNA-binding by Next Generation Sequencing

Rene Jackstadt, Markus Kaller, Antje Menssen, and Heiko Hermeking

8. Analysis of Myc Chromatin Binding by Calibrated ChIP-seq Approach

Donald P. Cameron, Vladislav Kuzin, and Laura Baranello

9. A High-Throughput Chromatin Immunoprecipitation Sequencing Approach to Study the Role of MYC on the Epigenetic Landscape

Luca Fagnocchi and Alessio Zippo

10. Methods for Determining Myc-induced Apoptosis

Dan Lu, Catherine Wilson, and Trevor D. Littlewood

11. Measuring MYC-mediated Metabolism in Tumorigenesis

Hsin-Yao Tang, Aaron R. Goldman, Xue Zhang, David W. Speicher, and Chi V. Dang

12. Methods to study Myc-regulated Cellular Senescence - An Update

Fan Zhang, Wesam Bazzar, Mohammad Alzrigat, and Lars-Gunnar Larsson

13. Examining Myc-Dependent Translation Changes in Cellular Homeostasis and Cancer

Joanna R. Kovalski, Yichen Xu, and Davide Ruggero

14. A Versatile in vivo System to Study Myc in Cell Reprogramming

Elena Senis, Lluc Mosteiro, Dirk Grimm, and Maria Abad

15. Using Flow Cytometry to Study Mycs Role in Shaping the Tumor Immune Microenvironment

Sнlvia Casacuberta-Serra

16. Generation of a Tetracycline Regulated Mouse Model of MYC-Induced

T-Cell Acute Lymphoblastic Leukemia

Wadie D. Mahauad-Fernandez, Kavya Rakhra, and Dean W. Felsher

17. Chromogenic in Situ Hybridization (CISH) as a Method for Detection of C-Myc Amplification in Formalin-Fixed Paraffin-Embedded Tumor Tissue: An Update

Natasa Todorovic-Rakovic

18. MYC Copy Number Detection in Clinical Samples using a Digital DNA-Hybridization and Detection Method

Zighereda Ogbah, Francesco Mattia Mancuso, and Ana Vivancos

19. Cell-Based Methods for the Identification of Myc-Inhibitory Small Molecules

Catherine A. Burkhart, Michelle Haber, Murray D. Norris, Andrei V. Gudkov, and Mikhail A. Nikiforov




In Situ Detection of DNA Damage / Methods and Protocols

Автор: Didenko Vladimir V.
Название: In Situ Detection of DNA Damage / Methods and Protocols
ISBN: 0896039528 ISBN-13(EAN): 9780896039520
Издательство: Springer
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Цена: 5809.00 р.
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Описание: In In Situ Detection of DNA Damage: Methods and Protocols, Vladimir Didenko and a panel of experts describe all the major in situ techniques for studying DNA damage and apoptosis, and how approaches originally designed to label apoptotic cells can be used for DNA damage analysis (and vice versa). The readily reproducible techniques presented here include all those designed to detect specific single- and double-stranded DNA breaks in tissue sections while using polymerases, ligases, nucleases, and kinases. There are also novel instrumental techniques that use ultrasound for in vivo and in situ detection of apoptotic DNA damage, and in situ applications of flow and laser-scanning cytometry for analysis of DNA strand breaks and apoptosis. State-of-the-art and highly practical, In Situ Detection of DNA Damage: Methods and Protocols presents for the first time a complete set of enzymatic methods for determining DNA breaks, and will greatly facilitate the work of all those studying the in situ detection of DNA damage and the labeling of apoptotic cells.

Affinity Chromatography / Methods and Protocols

Автор: Zachariou Michael
Название: Affinity Chromatography / Methods and Protocols
ISBN: 1588296598 ISBN-13(EAN): 9781588296597
Издательство: Springer
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Цена: 2000.00 р.
Наличие на складе: Есть (2 шт.)
Описание: Thirty-eight years after its introduction, affinity chromatography remains a key tool in th armory of separation techniques available to separation and interaction scientists.  Expanded and updated from the first edition, this second edition volume aims to provide the beginner with the practical knowledge needed to develop affinity separations suitable for a variety of applications relevant to the post-genomic era.

Mycroft Holmes

Автор: Abdul-Jabbar Kareem, Waterhouse Anna
Название: Mycroft Holmes
ISBN: 1783291532 ISBN-13(EAN): 9781783291533
Издательство: Titan books ltd.
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Цена: 2790.00 р.
Наличие на складе: Поставка под заказ.

Описание: This story occurs when Mycroft, an athletic Cambridge graduate, assisted the Secretary of State. He becomes embroiled in a mystery in Trinidad - based on actual history.

Mycroft and Sherlock

Автор: Abdul-Jabbar Kareem, Waterhouse Anna
Название: Mycroft and Sherlock
ISBN: 1785659251 ISBN-13(EAN): 9781785659256
Издательство: Titan books ltd.
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Цена: 2790.00 р.
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Описание: The new novel by NBA All-Star Kareem Abdul-Jabbar, starring brothers Mycroft and Sherlock Holmes.

Political Science Research Methods

Автор: Janet Buttolph Johnson, H. T. Reynolds, Jason D. Mycoff
Название: Political Science Research Methods
ISBN: 1544331436 ISBN-13(EAN): 9781544331430
Издательство: Sage Publications
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Цена: 21067.00 р.
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Описание: Political Science Research Methods helps students to understand the logic behind research design by guiding them through a step-by-step process that explains when and why a researcher would pursue different kinds of methods.

The Myc/Max/Mad Transcription Factor Network

Автор: Robert N. Eisenman
Название: The Myc/Max/Mad Transcription Factor Network
ISBN: 3642421415 ISBN-13(EAN): 9783642421419
Издательство: Springer
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Цена: 27950.00 р.
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Описание: Scientists often look askance at their colleagues whose research appears too strongly focused on a single gene or gene product. We are supposed to be interested in the “big picture” and excessive zeal in pursuit of a single pixel might seem to border on an obsession that is likely to yield only details. However as this volume of Current Topics in Microbiology and Immunology demonstrates, this is certainly not the case for myc. Intense study of this en- matic proto-oncogene over the last twenty years has only broadened our view of its functions and led to insights into mechanisms relating to transcriptional regulation as well as to cell growth, proliferation, differentiation, apoptosis and organismal development. The myc gene originally came to light as a retroviral oncogene (v-myc) associated with a wide range of acute neoplasms. It was later shown to be a virally transduced cellular gene (c-myc) which is a member of family of on- genes (c-myc,N-myc,L-myc). These family members are themselves subject to a bewildering assortment of genetic rearrangements associated with many different types of tumors derived from many different types of cells. These rearrangements (including chromosomal translocation, viral integration, and gene ampli?cation) act to uncouple expression of the myc family genes from their normal physiological regulators. The chapter by LIU and LEVENS - scribes the key pathways leading to regulation of myc expression, showing that such regulation occurs at several different levels and through multiple mechanisms.

The Myc Gene

Автор: Laura Soucek; Nicole M. Sodir
Название: The Myc Gene
ISBN: 1493960172 ISBN-13(EAN): 9781493960170
Издательство: Springer
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Цена: 14673.00 р.
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Описание: In The Myc Gene: Methods and Protocols, experts in the field summarize the standard and novel techniques that allow the studying of Myc mechanism of action in normal and cancer cells, in vitro and in vivo.

Myc Gene

Название: Myc Gene
ISBN: 1627034285 ISBN-13(EAN): 9781627034289
Издательство: Springer
Рейтинг:
Цена: 14673.00 р.
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Описание: In The Myc Gene: Methods and Protocols, experts in the field summarize the standard and novel techniques that allow the studying of Myc mechanism of action in normal and cancer cells, in vitro and in vivo.

The Age of Netflix: Critical Essays on Streaming Media, Digital Delivery and Instant Access

Автор: Wiatrowski Myc
Название: The Age of Netflix: Critical Essays on Streaming Media, Digital Delivery and Instant Access
ISBN: 0786497475 ISBN-13(EAN): 9780786497478
Издательство: Mare Nostrum (Eurospan)
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Цена: 4990.00 р.
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Описание: Collecting several new essays from scholars around the globe, this collection seeks to participate in the ongoing discourse about Netflix`s place in contemporary culture. These contributors explore the intricacies of the enormous effect Netflix has had on how we consume popular media in the everyday world and examines the streaming giant as a disruptor and cultural institution.

C-Myc in B-Cell Neoplasia

Автор: Michael Potter; Fritz Melchers
Название: C-Myc in B-Cell Neoplasia
ISBN: 3642645607 ISBN-13(EAN): 9783642645600
Издательство: Springer
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Цена: 18167.00 р.
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Описание: The papers in this book were presented at the 14th Mechanisms in B-cell Neoplasia meeting that was held in Bethesda, Maryland October 21-23, 1996. , for their outstanding organizational assistance. With 2 Figures . . . . . . . . . . . . . . . . . . . . . . . .

Arrow and Superhero Television: Essays on Themes and Characters of the Series

Автор: James F. Iaccino, Cory Barker, Myc Wiatrowski
Название: Arrow and Superhero Television: Essays on Themes and Characters of the Series
ISBN: 0786497874 ISBN-13(EAN): 9780786497874
Издательство: Mare Nostrum (Eurospan)
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Цена: 3326.00 р.
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Описание: This collection of new essays focuses on The CW network`s hit television series Arrow - based on DC Comic`s Green Arrow - and its spin-offs. The contributors explore the reasons behind Arrow`s success, the series` representation of bodies, its portrayal of women, its shifting political ideologies, and audience reception and influence on storylines.

c-Myc Function in Neoplasia

Автор: C.V. Dang; Linda A. Lee
Название: c-Myc Function in Neoplasia
ISBN: 3662226839 ISBN-13(EAN): 9783662226834
Издательство: Springer
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Цена: 15672.00 р.
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Описание: c-myc was one of the very first proto- oncogenes to be identified and because it normally plays pivotal roles in both cell proliferation and cell death has enticed many to investigate the molecular mechanisms by which it transforms cells.


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