The Myc Gene: Methods and Protocols, Soucek Laura, Whitfield Jonathan

Автор: Didenko Vladimir V.
Название: In Situ Detection of DNA Damage / Methods and Protocols
ISBN: 0896039528 ISBN-13(EAN): 9780896039520
Издательство: Springer
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Описание: In In Situ Detection of DNA Damage: Methods and Protocols, Vladimir Didenko and a panel of experts describe all the major in situ techniques for studying DNA damage and apoptosis, and how approaches originally designed to label apoptotic cells can be used for DNA damage analysis (and vice versa). The readily reproducible techniques presented here include all those designed to detect specific single- and double-stranded DNA breaks in tissue sections while using polymerases, ligases, nucleases, and kinases. There are also novel instrumental techniques that use ultrasound for in vivo and in situ detection of apoptotic DNA damage, and in situ applications of flow and laser-scanning cytometry for analysis of DNA strand breaks and apoptosis. State-of-the-art and highly practical, In Situ Detection of DNA Damage: Methods and Protocols presents for the first time a complete set of enzymatic methods for determining DNA breaks, and will greatly facilitate the work of all those studying the in situ detection of DNA damage and the labeling of apoptotic cells.

Автор: Zachariou Michael
Название: Affinity Chromatography / Methods and Protocols
ISBN: 1588296598 ISBN-13(EAN): 9781588296597
Издательство: Springer
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Описание: Thirty-eight years after its introduction, affinity chromatography remains a key tool in th armory of separation techniques available to separation and interaction scientists.  Expanded and updated from the first edition, this second edition volume aims to provide the beginner with the practical knowledge needed to develop affinity separations suitable for a variety of applications relevant to the post-genomic era.

Автор: Elvin John
Название: Sherlock Holmes and the Eye of Mad Bear: Based on the Notes of Mycroft Holmes
ISBN: 0992965330 ISBN-13(EAN): 9780992965334
Издательство: Неизвестно
Цена: 1723.00 р.
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Автор: Laura Soucek; Nicole M. Sodir
Название: The Myc Gene
ISBN: 1493960172 ISBN-13(EAN): 9781493960170
Издательство: Springer
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Цена: 14673.00 р.
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Описание: In The Myc Gene: Methods and Protocols, experts in the field summarize the standard and novel techniques that allow the studying of Myc mechanism of action in normal and cancer cells, in vitro and in vivo.

Название: Myc Gene
ISBN: 1627034285 ISBN-13(EAN): 9781627034289
Издательство: Springer
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Цена: 14673.00 р.
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Описание: In The Myc Gene: Methods and Protocols, experts in the field summarize the standard and novel techniques that allow the studying of Myc mechanism of action in normal and cancer cells, in vitro and in vivo.

Автор: Wiatrowski Myc
Название: The Age of Netflix: Critical Essays on Streaming Media, Digital Delivery and Instant Access
ISBN: 0786497475 ISBN-13(EAN): 9780786497478
Издательство: Mare Nostrum (Eurospan)
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Цена: 4990.00 р.
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Описание: Collecting several new essays from scholars around the globe, this collection seeks to participate in the ongoing discourse about Netflix`s place in contemporary culture. These contributors explore the intricacies of the enormous effect Netflix has had on how we consume popular media in the everyday world and examines the streaming giant as a disruptor and cultural institution.

Автор: Michael Potter; Fritz Melchers
Название: C-Myc in B-Cell Neoplasia
ISBN: 3642645607 ISBN-13(EAN): 9783642645600
Издательство: Springer
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Цена: 18167.00 р.
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Описание: The papers in this book were presented at the 14th Mechanisms in B-cell Neoplasia meeting that was held in Bethesda, Maryland October 21-23, 1996. , for their outstanding organizational assistance. With 2 Figures . . . . . . . . . . . . . . . . . . . . . . . .

Автор: James F. Iaccino, Cory Barker, Myc Wiatrowski
Название: Arrow and Superhero Television: Essays on Themes and Characters of the Series
ISBN: 0786497874 ISBN-13(EAN): 9780786497874
Издательство: Mare Nostrum (Eurospan)
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Цена: 3326.00 р.
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Описание: This collection of new essays focuses on The CW network`s hit television series Arrow - based on DC Comic`s Green Arrow - and its spin-offs. The contributors explore the reasons behind Arrow`s success, the series` representation of bodies, its portrayal of women, its shifting political ideologies, and audience reception and influence on storylines.

Автор: C.V. Dang; Linda A. Lee
Название: c-Myc Function in Neoplasia
ISBN: 3662226839 ISBN-13(EAN): 9783662226834
Издательство: Springer
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Цена: 15672.00 р.
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Описание: c-myc was one of the very first proto- oncogenes to be identified and because it normally plays pivotal roles in both cell proliferation and cell death has enticed many to investigate the molecular mechanisms by which it transforms cells.

Автор: Robert N. Eisenman
Название: The Myc/Max/Mad Transcription Factor Network
ISBN: 3642421415 ISBN-13(EAN): 9783642421419
Издательство: Springer
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Цена: 27950.00 р.
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Описание: Scientists often look askance at their colleagues whose research appears too strongly focused on a single gene or gene product. We are supposed to be interested in the “big picture” and excessive zeal in pursuit of a single pixel might seem to border on an obsession that is likely to yield only details. However as this volume of Current Topics in Microbiology and Immunology demonstrates, this is certainly not the case for myc. Intense study of this en- matic proto-oncogene over the last twenty years has only broadened our view of its functions and led to insights into mechanisms relating to transcriptional regulation as well as to cell growth, proliferation, differentiation, apoptosis and organismal development. The myc gene originally came to light as a retroviral oncogene (v-myc) associated with a wide range of acute neoplasms. It was later shown to be a virally transduced cellular gene (c-myc) which is a member of family of on- genes (c-myc,N-myc,L-myc). These family members are themselves subject to a bewildering assortment of genetic rearrangements associated with many different types of tumors derived from many different types of cells. These rearrangements (including chromosomal translocation, viral integration, and gene ampli?cation) act to uncouple expression of the myc family genes from their normal physiological regulators. The chapter by LIU and LEVENS - scribes the key pathways leading to regulation of myc expression, showing that such regulation occurs at several different levels and through multiple mechanisms.

Автор: Abdul-Jabbar Kareem, Waterhouse Anna
Название: Mycroft and Sherlock
ISBN: 1785659251 ISBN-13(EAN): 9781785659256
Издательство: Titan books ltd.
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Цена: 2790.00 р.
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Описание: The new novel by NBA All-Star Kareem Abdul-Jabbar, starring brothers Mycroft and Sherlock Holmes.

Автор: John C. Barrett, Michael J. Boyd
Название: From Stonehenge to Mycenae: The Challenges of Archaeological Interpretation
ISBN: 1474291899 ISBN-13(EAN): 9781474291897
Издательство: Bloomsbury Academic
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Цена: 14256.00 р.
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Описание:

This book reconsiders how we can understand archaeology on a grand scale by abandoning the claims that material remains stand for the people and institutions that produced them, or that genetic change somehow caused cultural change. Our challenge is to understand the worlds that made great projects like the building of Stonehenge or Mycenae possible. The radiocarbon revolution made the old view that the architecture of Mycenae influenced the building of Stonehenge untenable. But the recent use of 'big data' and of genetic histories have led archaeology back to a worldview where 'big problems' are assumed to require 'big solutions'.

Making an animated plea for bottom-up rather than top-down solutions, the authors consider how life was made possible by living in the local and materially distinct worlds of the period. By considering how people once built connections between each other through their production and use of things, their movement between and occupancy of places, and their treatment of the dead, we learn about the kinds of identities that people constructed for themselves. Stonehenge did not require an architect from Mycenae for it to be built, but the builders of Stonehenge and Mycenae would have shared a mutual recognition of the kinds of humans that they were, and the kinds of practices these monuments were once host to.