Single-cell Sequencing and Methylation: Methods and Clinical Applications, Yu Buwei, Zhang Jiaqiang, Zeng Yiming
Автор: Urszula Demkow Название: Clinical Applications for Next Generation Sequencing ISBN: 0128017392 ISBN-13(EAN): 9780128017395 Издательство: Elsevier Science Рейтинг: Цена: 12462.00 р. Наличие на складе: Поставка под заказ.
Описание:
Clinical Applications for Next Generation Sequencing provides readers with an outstanding postgraduate resource to learn about the translational use of NGS in clinical environments.
Rooted in both medical genetics and clinical medicine, the book fills the gap between state-of-the-art technology and evidence-based practice, providing an educational opportunity for users to advance patient care by transferring NGS to the needs of real-world patients.
The book builds an interface between genetic laboratory staff and clinical health workers to not only improve communication, but also strengthen cooperation. Users will find valuable tactics they can use to build a systematic framework for understanding the role of NGS testing in both common and rare diseases and conditions, from prenatal care, like chromosomal abnormalities, up to advanced age problems like dementia.
Автор: Lusser Alexandra Название: RNA Methylation: Methods and Protocols ISBN: 1493983040 ISBN-13(EAN): 9781493983049 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides a comprehensive collection of current methods and protocols to study posttranscriptional base modifications in RNA with special focus on methylation.
Rapid technological developments have led to increasingly efficient sequencing approaches. Next Generation Sequencing (NGS) is increasingly common and has become cost-effective, generating an explosion of sequenced data that need to be analyzed. The skills required to apply computational analysis to target research on a wide range of applications that include identifying causes of cancer, vaccine design, new antibiotics, drug development, personalized medicine and higher crop yields in agriculture are highly sought after.
This invaluable book provides step-by-step guides to complex topics that make it easy for readers to perform essential analyses from raw sequenced data to answering important biological questions. It is an excellent hands-on material for teachers who conduct courses in bioinformatics and as a reference material for professionals. The chapters are written to be standalone recipes making it suitable for readers who wish to self-learn selected topics. Readers will gain skills necessary to work on sequenced data from NGS platforms and hence making themselves more attractive to employers who need skilled bioinformaticians to handle the deluge of data.
Автор: Malcolm Billy Название: DNA Methylation: Principles, Methods and Mechanisms ISBN: 168286412X ISBN-13(EAN): 9781682864128 Издательство: Неизвестно Рейтинг: Цена: 24299.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: DNA Methylation can be defined as the method by which methyl groups act on the DNA in order to repress cell processes. DNA methylation is vital for the organic processes taking place inside the human body such as ageing, carcinogenesis and gene expression. The aim of this book is to present researchers that have transformed this discipline and added its advancement. From theories and research to practical applications, case studies related to all contemporary topics of relevance to this field have been included herein. This book will prove useful for students as well as experts in the fields of evolutionary biology, bioengineering, and biochemistry. It is an essential guide for both academicians as well as for those who wish to pursue this discipline further.
Автор: Tan T. W., Lee Eric Название: Beginners Guide to Bioinformatics for High Throughput Sequencing ISBN: 9813231661 ISBN-13(EAN): 9789813231665 Издательство: World Scientific Publishing Рейтинг: Цена: 8712.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Biologists find computing bewildering; yet they are expected to be able to process the voluminous data available from the machines they buy and the datasets that has accumulated in genomic databanks worldwide. It is now increasingly difficult for them to avoid dealing with large volumes of data, that goes beyond just doing manual programming.
Most books in this realm are full of equations and complex code but this book gives a much gentler entry point particularly for biologists, with code snippets users can use to cut and paste, and run on their Linux or MacOSX operating system or cloud instance. It also provides a step by step installation instructions which they can easily follow. Those who are in the field of genome sequencing and already familiar with the procedures of analysis, may also find this book useful in closing some knowledge gaps.
High throughput sequencing requires high throughput and high performance computing. This book provides a gentle entry to high throughput sequencing by dealing with simple skills which the average biologist is increasingly required to master. You will find this book a breeze to read, and some suggestions in this book maybe new to you, something you might want to try out.
Описание: With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers.
Автор: Moshe Szyf Название: DNA Methylation and Cancer Therapy ISBN: 1441934162 ISBN-13(EAN): 9781441934161 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Once techniques to probe the methylation profile of whole genomes as well as specific genes became available, it became clear that DNA methylation patterns are gene and tissue specific and that patterns of gene expression correlate with patterns of methylation.
Автор: Atsushi Kaneda; Yu-ichi Tsukada Название: DNA and Histone Methylation as Cancer Targets ISBN: 3319597841 ISBN-13(EAN): 9783319597843 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book will focus on DNA and histone methylation in epigenetics and describe how it is involved in the molecular mechanisms responsible for the development of cancer. Chapters will summarize the current knowledge of the molecular basis of DNA and histone methylation and explain how it is involved in cancer, describe the features of DNA and histone methylation associated with particular types of cancer, diagnostic/therapeutic applications, and future directions of DNA and histone methylation as cancer targets.
Автор: J. Jost; H. Saluz Название: DNA Methylation ISBN: 3034899157 ISBN-13(EAN): 9783034899154 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The explosive increase in the number of publications dealing with DNA methylation attests to its importance and makes it impossible to write a comprehensive coverage of the literature within the scope of a general review. Since the publication of the 3 most recent books dealing with the subject (DNA methylation by Razin A.
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