Автор: Benjamin M.J Owens; Matthew A. Lakins Название: Stromal Immunology ISBN: 3030086216 ISBN-13(EAN): 9783030086213 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Research into and interest in the role of stromal cells in immunology has exploded over the past 15 years. The conventional view that placed non-hematopoietic stromal cells as passive, structural, and supportive entities has now been replaced with an appreciation that these cells have active, dynamic roles during immune responses, and thus impact on the pathophysiology of multiple immune-mediated diseases. This book serves to provide solid grounding in the fundamentals of stromal immunology, focusing on the biological aspects of their function in addition to highlighting key areas for the development of the field in the future. The book is also a unique source of information on emerging concepts that place stromal cells from outside lymphoid organs as major contributors to the biology of diverse conditions, such as rheumatoid arthritis, chronic parasitic infection, inflammatory bowel disease, and cancer.
Автор: Koji Yasutomo Название: Notch Signaling ISBN: 9811352801 ISBN-13(EAN): 9789811352805 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Поставка под заказ.
Описание: Also, the studies regarding the functions of Notch in immune cells and tumor cells have motivated researchers and pharmaceutical companies to develop drugs for treating immune-mediated diseases and tumors.
Описание: This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer.
1. Notch signaling in prevention ant therapy: fighting cancer with a two-sided sword
2. Transcription factor RBPJ as a molecular switch in regulating the Notch response
3. Unraveling of Hidden Secrets: The tumour suppressor Lethal (2) giant discs (Lgd)/CC2D1, Notch Signaling and Cancer
4. Notch and endometrial cancer
5. Notch and Esophageal Squamous Cell Carcinoma
6. Notch signaling and liver cancer
7. Notch inHead and Neck Cancer
8. Notch Signaling and Human Papillomavirus-Associated Oral Tumorigenesis
9. The impact of Notch signalingfor carcinogenesis and progression of non-melanoma skin cancer: lessons learned fromcancer stem cells, tumor angiogenesis, and beyond
10. Notch Signaling in Thyroid Cancer
11. The Relevance of Notch Signaling in Cancer Progression
12. Notch Signaling and the Breast Cancer Microenvironment
13. Notch pathway: a journey from notching phenotypes to cancer immunotherapy
Index
Автор: Peiman Hematti; Armand Keating Название: Mesenchymal Stromal Cells ISBN: 1493941291 ISBN-13(EAN): 9781493941292 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this book, leading authorities actively involved in this field provide state-of-the-art knowledge of the basic biology, translational requirements and latest clinical experience with Mesenchymal Stromal Cell (MSC) biology.
Автор: Peiman, Hematti Название: Mesenchymal Stromal Cells ISBN: 0128028262 ISBN-13(EAN): 9780128028261 Издательство: Elsevier Science Рейтинг: Цена: 14654.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Mesenchymal Stromal Cells: Translational Pathways to Clinical Adoption provides the latest information on the necessary steps for successful production of stem cells for a clinical trial. Written by professionals with hands-on experience in bringing MSC therapies to the clinic, and building on the biology and mechanisms of action, this unique book covers the development and production of clinical-grade products that are suitable for use in humans. From design of a cell production facility, to obtaining regulatory approval and reimbursement issues, it is a useful guide for researchers and administrators across biomedical research.
Автор: Mariana Garcia Название: Mesenchymal Stromal Cells as Tumor Stromal Modulators ISBN: 0128031026 ISBN-13(EAN): 9780128031025 Издательство: Elsevier Science Рейтинг: Цена: 18696.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Mesenchymal stromal/ stem cells (MSCs) represent a heterogeneous cell population with immunomodulating, tissue repairing, differentiating, migratory and angiogenic abilities, making them important tools for clinical and translational research. An understanding of the role of MSCs in modulating tumor growth provides a glimpse into their role in non-pathological tissue remodeling and potential regenerative tissue therapies. Mesenchymal Stromal Cells as Tumor Stromal Modulators is a comprehensive source for the understanding of the role of MSCs as ubiquitous connective tissue cell components, which may have both direct and indirect effects on the tumor microenvironment and potential for regenerative therapeutics for various diseases. Using cancer as a model disease, this book explores the transformative role MSCs play in the recruitment of disease cells, cell repair and immunological defenses.
Автор: Owens Название: Stromal Immunology ISBN: 3319781251 ISBN-13(EAN): 9783319781259 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Research into and interest in the role of stromal cells in immunology has exploded over the past 15 years.
Автор: Weimbs, Thomas Название: Methods In Kidney Cell Biology Part B,154 ISBN: 0128203358 ISBN-13(EAN): 9780128203354 Издательство: Elsevier Science Рейтинг: Цена: 23412.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Methods in Kidney Cell Biology, Part B, Volume 154 represents state-of-the-art techniques in renal research that are ideal for veterans, graduate students, postdoctoral fellows, clinical scientists and principal investigators. Topics in the new release include Single glomerular proteomics - a novel method in translational glomerular cell biology, Measurement of cytosolic and intraciliary calcium in live cells, Differentiation of human kidney organoids from pluripotent stem cells, Quantifying autophagic flux in kidney tissue using structured illumination microscopy, the Generation of primary cells from ADPKD and normal human kidneys, ADPKD cell proliferation and Cl-dependent fluid secretion, In vitro cyst formation of ADPKD cells, and much more.
Описание: This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer.
