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Natural Products from Actinomycetes: Diversity, Ecology and Drug Discovery, Rai Ravishankar V., Bai Jamuna a.


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Автор: Rai Ravishankar V., Bai Jamuna a.
Название:  Natural Products from Actinomycetes: Diversity, Ecology and Drug Discovery
ISBN: 9789811661310
Издательство: Springer
Классификация:



ISBN-10: 9811661316
Обложка/Формат: Hardcover
Страницы: 524
Вес: 0.90 кг.
Дата издания: 16.04.2022
Язык: English
Издание: 1st ed. 2022
Иллюстрации: 25 tables, color; 1 illustrations, black and white; xiv, 508 p. 1 illus.
Размер: 23.39 x 15.60 x 2.87 cm
Читательская аудитория: Professional & vocational
Подзаголовок: Diversity, ecology and drug discovery
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This book provides in-depth information about the ecology, diversity and applications of Actinomycetes. The book is divided into two major parts. The first part discusses the diversity, chemical biology and ecology of Actinomycetes. It also covers the discovery of natural products from soil, endophytic and marine-derived Actinomycetes. It includes natural product discovery, chemical biology, new methods for discovering secondary metabolites, structure elucidation and biosynthetic research of natural products. The chapters in this part focus on the effects of biological and chemical elicitation at molecular level on secondary metabolism in Actinomycetes. The second part of the book discusses genomic and synthetic biology approaches in Actinomycetes drug discovery. This part includes chapters focused on the application of metabolic engineering to optimize natural product synthesis and the use of omics data in engineering of regulatory genes. It covers the advanced tools of synthetic biology and metabolic engineering including cluster assembly, CRISPR/Cas9 technologies, and chassis strain development for natural product overproduction in Actinomycetes. It describes the use of bioinformatics tools for reprogramming of biosynthetic pathways through polyketide synthase and non-ribosomal peptide synthetase engineering. These advanced genomic and molecular tools are expected to accelerate the discovery and development of new natural products from Actinomycetes with medicinal and other industrial applications. The book is useful to researchers and students in the field of microbiology, pharmaceutical sciences and drug discovery.
Дополнительное описание: Chapter 1. Dimensional Research on Actinomycetes.- Chapter 2. Isolation of Actinobacteria from uncommon habitats like insects and mollusks.- Chapter 3. Diversity, Chemical biology and Ecology of Actinomycetes and the Discovery of Natural Products.- Chapte



Natural Products and Cancer Drug Discovery

Автор: Frank E. Koehn
Название: Natural Products and Cancer Drug Discovery
ISBN: 148999565X ISBN-13(EAN): 9781489995650
Издательство: Springer
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Цена: 22201.00 р.
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Описание: With reliable commentary and analysis in a sector often associated with outlandish claims, this volume provides a valuable overview of how natural products could generate new cancer therapeutics as well as mitigating the deleterious effects of chemotherapy.

A Closer Look at Actinomycetes

Автор: A. A. Mohamed Hatha
Название: A Closer Look at Actinomycetes
ISBN: 1536170461 ISBN-13(EAN): 9781536170467
Издательство: Nova Science
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Цена: 27402.00 р.
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Описание: Actinomycetes are a versatile group of Gram positive bacteria widely distributed in the terrestrial and aquatic environments. The specialty of the actinomycetes is that they have a mycelial appearance unlike most bacteria. This group of bacteria is well known for their ability to produce a range of bioactive molecules, including antibiotics and various kinds of enzymes. As they are known for their ability to produce various antibiotics, the actinomycetes are widely explored by various research groups in search of novel drug molecules. Since the cultivation and maintenance of actinobacteria are not that easy as in the case of other bacteria, they are rather underexplored. With the frequent emergence of multidrug resistant bacteria, which are outpacing the discovery of new antibiotics, there is a renewed interest in actinomycetes from special habitats such as extreme habitats in the marine environment, salt pans, geothermal springs, permanently frozen polar environments etc. Endophytic actinomycetes are also attracting the attention of current researchers in this field. This book titled "A Closer Look at Actinomycetes" is a compilation of articles which deals with interesting topics such as "actinomycetes as microbial drug factories", endophytic fungi from special habitats of Pakistan as well as strategies for exploration of actinomycetes diversity and the taxonomy of actinomycetes should be of great interest to those who are interested in Actinomycetes research. People with interest in general microbiology will also find it an interesting read.

Drug Discovery from Natural Products

Название: Drug Discovery from Natural Products
ISBN: 1849733619 ISBN-13(EAN): 9781849733618
Издательство: Royal Society of Chemistry
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Цена: 33790.00 р.
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Описание: An integrated review of the most recent trends in natural products drug discovery and key lead candidates that are outstanding for their chemistry and biology in novel drug development.

The Role of Natural Products in Drug Discovery

Автор: J. Mulzer; R. Bohlmann
Название: The Role of Natural Products in Drug Discovery
ISBN: 3662040441 ISBN-13(EAN): 9783662040447
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Natural Products have been important sources of useful drugs from prehistoric times to the present. This book gives an overview about this field and provides important recent contributions to the discovery of new drugs generated by research on natural products.

Discovery And Development Of Anti-Inflammatory Agents From Natural Products

Автор: Brahmachari, Goutam
Название: Discovery And Development Of Anti-Inflammatory Agents From Natural Products
ISBN: 0128169923 ISBN-13(EAN): 9780128169926
Издательство: Elsevier Science
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Цена: 28633.00 р.
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Описание:

Discovery and Development of Anti-inflammatory Agents from Natural Products, the latest volume in the Natural Product Drug Discovery series, presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations, with this volume focusing on molecules of natural origin and their synthetic analogues that have the potential to act against the pathogens responsible for inflammatory diseases. All aspects of each are covered, including isolations and structure elucidations, in vitro and in vivo biological activity, synthetic optimization, investigations of pharmacodynamics and kinetics, and the structure-activity relationships of anti-inflammatory natural products.

Written by active researchers and leading experts, this book brings together an overview of current discoveries and trends in this field. It will be a valuable resource for researchers working to discover promising leads for the development of pharmaceuticals in the prevention and treatment of anti-inflammatory diseases.

Bioactive Natural Products in Drug Discovery

Автор: Singh Joginder, Meshram Vineet, Gupta Mahiti
Название: Bioactive Natural Products in Drug Discovery
ISBN: 9811513961 ISBN-13(EAN): 9789811513961
Издательство: Springer
Цена: 13974.00 р.
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Описание: This book highlights different natural products that are derived from the plants and microbes that have shown potential as the lead compounds against infectious diseases and cancer.

Bioactive Natural Products in Drug Discovery

Автор: Singh Joginder, Meshram Vineet, Gupta Mahiti
Название: Bioactive Natural Products in Drug Discovery
ISBN: 9811513937 ISBN-13(EAN): 9789811513930
Издательство: Springer
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Цена: 13974.00 р.
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Описание: This book highlights different natural products that are derived from the plants and microbes that have shown potential as the lead compounds against infectious diseases and cancer.

Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases

Автор: Brahmachari, Goutam
Название: Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases
ISBN: 0128157232 ISBN-13(EAN): 9780128157237
Издательство: Elsevier Science
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Цена: 28970.00 р.
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Описание:

Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting points for the design of drugs against Neglected Tropical Diseases (NTDs). From the prediction of promising leads and identification of active agents, to the extraction of complex molecules, the book explores novel, economical and efficacious therapeutics for these diseases. It describes current research and the role of natural products, antimalarial compounds from marine natural products and sesquiterpene lactones, natural antileprotic agents, natural products with potential against Leishmaniasis, Trypanosomiasis and Dengue, and more.

In addition, Quinoline and Isoquinoline alkaloids for developing new antiprotozoal agents are discussed, alongside anti-trypanosomatid heterocyclic compounds as structures for development. Combining the expertise of specialists from around the world, this volume aims to support and encourage researchers in the investigation of natural sources as starting points for the development of novel, safe and effective agents for use against neglected tropical diseases.

  • Includes chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery
  • Draws together cutting-edge research advances in natural product chemistry that are targeted at neglected tropical diseases
  • Highlights the future potential of natural products as sources of novel medicinal compounds against neglected tropical diseases

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