Cancer Cell Signaling: Methods and Protocols, Robles-Flores Martha
Автор: Li Xiaochun Название: Hedgehog Signaling: Methods and Protocols ISBN: 1071617001 ISBN-13(EAN): 9781071617007 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This detailed book explores the technical breakthroughs with biophysical and cell biological approaches that have advanced the study of molecular mechanisms underlying the generation and transduction of the hedgehog (HH) signal, indicating the important role of sterols in this pathway. Within its pages, the volume examines techniques involving several key protein components in this pathway, including HH, the signaling ligand; Dispatched, a HH secretion regulator; Patched, the receptor of HH; Smoothened, the signal transducer used to transduce the HH signal across the plasma membrane; and GLI, the transcription factor to turn on HH target genes. Written in the highly successful Methods in Molecular Biology series format, chapters feature introductions to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Hedgehog Signaling: Methods and Protocols provides researchers in clinical and basic science with a fresh and reliable reference for analyzing HH signal transduction through cell biological, biochemical, and biophysical approaches.
Автор: Yotnda Patricia Название: Immunotherapy of Cancer: Methods and Protocols ISBN: 1493957538 ISBN-13(EAN): 9781493957538 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A continuously evolving technique, immunotherapy for the treatment of cancers now incorporates the use of immune cells infused during bone marrow transplants as well as approaches like cell and gene therapy, while stem cell-based therapies, tissue engineering, and targeting have also contributed to the latest successes in pre-clinical immunotherapy studies. In Immunotherapy of Cancer: Methods and Protocols, expert researchers in the field describe detailed procedures for trainees and experts in the area of basic, clinical science who wish to undertake their own cutting-edge immunotherapy studies. In addition to the protocols, the volume also contains two general overviews providing useful updates in each area as well as summaries of recent pre-clinical and clinical trials. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Immunotherapy of Cancer: Methods and Protocols seeks to guide scientists along the path to a further developed system of immunotherapeutic treatments in order to reduce and hopefully eradicate this terrible disease.
Автор: Wan Thomas S. K. Название: Cancer Cytogenetics: Methods and Protocols ISBN: 1493982788 ISBN-13(EAN): 9781493982783 Издательство: Springer Рейтинг: Цена: 11878.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Preface... Table of Contents... Contributing Authors...
1. Cancer Cytogenetics: An Introduction
Thomas S.K. Wan
2. Chromosome Preparation for Myeloid Malignancies
Eleanor K.C. Hui, Thomas S.K. Wan, and Margaret H.L. Ng
3. Chromosome Preparation for Acute Lymphoblastic Leukemia
Mary Shago
4. Chromosome Preparation for Chronic Lymphoid Malignancies
Dorota Koczkodaj and Agata A. Filip
5. Cytogenetic Harvesting of Cancer Cells and Cell Lines
Roderick A.F. MacLeod, Maren E. Kaufmann, and Hans G. Drexler
6. Chromosome Bandings
Huifang Huang and Jiadi Chen
7. Chromosome Recognition
Thomas S.K. Wan, Eleanor K.C. Hui, and Margaret H.L. Ng
8. Application of Fluorescence In Situ Hybridization Technology in Malignancies
Montakarn Tansatit
9. Fluorescence In Situ Hybridization Probe Preparation
Doron Tolomeo, Roscoe R. Stanyon, and Mariano Rocchi
10. Fluorescence In Situ Hybridization Probe Validation for Clinical Use
Jun Gu, Janice L. Smith, and Patricia K. Dowling
11. Fluorescence In Situ Hybridization on Tissue Sections
Alvin S.T. Lim and Tse Hui Lim
12. Cytoplasmic Immunoglobulin Light Chain Revelation and Interphase Fluorescence In Situ Hybridization in MyelomaSarah Moore, Jeffrey M. Suttle, and Mario Nicola
13. Quantitate Fluorescence In Situ Hybridization (QFISH)
Ivan Iourov
14. High Resolution of Fiber-Fluorescence In Situ Hybridization (Fiber-FISH)
Chengsheng Zhang, Eliza Cerveira, Mallory Romanovitch, and Qihui Zhu
16. Multicolor Karyotyping and Fluorescence In Situ Hybridization-Banding (MCB/mBAND)
Thomas Liehr, Moneeb A.K. Othman, and Katharina Rittscher
17. Cytogenetics for Biological Dosimetry
Michelle Ricoul, Tamizh Gnana-Sekaran, Laure Piqueret-Stephan, and Laure Sabatier
18. Recurrent Cytogenetic Abnormalities in Myelodysplastic Syndromes
Meaghan Wall
19. Recurrent Cytogenetic Abnormalities in Acute Myeloid Leukemia
John J. Yang, Tae Sung Park, and Thomas S.K. Wan
20. Recurrent Cytogenetic AJohn Swansbury
21. Recurrent Cytogenetic Abnormalities in Acute Lymphoid Leukemia
Mary Shago
22. Recurrent Cytogenetic Abnormalities in Non-Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia
Edmond S.K. Ma
23. Recurrent Cytogenetic Abnormalities in Multiple Myeloma
Nelson C.N. Chan and Natalie P.H. Chan
24. Cytogenetic Nomenclature and Reporting
Marian Stevens-Kroef, Annet Simons, Katrina Rack, and Rosalind J. Hastings
25. Cytogenetic Resources and Information
E. De Braekeleer, J. L. Huret, H. Mossafa, and P. Dessen
Автор: Webb Michelle Название: Cancer Susceptibility: Methods and Protocols ISBN: 1493957600 ISBN-13(EAN): 9781493957606 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Over the past two decades, spectacular advances have been made in our understanding of the molecular genetics of cancer, leading to the pursuit of identifying genes that, when mutated, result in an increased susceptibility to the disease. In Cancer Susceptibility: Methods and Protocols, experts in the field bring together the most recent technological developments for identifying and screening cancer susceptibility genes. Divided into two clear sections, the book begins with gene identification, which updates and informs scientists working at identifying novel cancer susceptibility genes, while the second part deals with mutation screening technologies that aid scientists and clinicians working to translate this knowledge into the clinic. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cancer Susceptibility: Methods and Protocols is a timely collection that seeks to provide researchers with the tools to predict and combat this terrible disease.
Описание: This volume focuses on a variety of in silico protocols of the latest bioinformatics tools and computational pipelines developed for neo-antigen identification and immune cell analysis from high-throughput sequencing data for cancer immunotherapy.
Автор: Zeineldin Reema Название: Cancer Nanotechnology: Methods and Protocols ISBN: 1493982591 ISBN-13(EAN): 9781493982592 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Part I: Overviews
1. Cancer Nanotechnology: Opportunities for Prevention, Diagnosis, and Therapy
Reema Zeineldin and Joan Syoufjy
2. Improved Targeting of Cancers with Nanotherapeutics
Christian Foster, Andre Watson, Joseph Kaplinsky, and Nazila Kamaly
Part II: Nanotechnology-Based Platforms
3. Multifunctional Liposomes
Bhawani Aryasomayajula, Giuseppina Salzano, and Vladimir P. Torchilin
4. Multifunctional Concentric FRET-Quantum Dot Probes for Tracking and Imaging of Proteolytic Activity
Melissa Massey, Jia Jun Li, and W. Russ Algar
5. Preparation and Characterization of Magnetic Nano-in-Microparticles for Pulmonary Delivery
Amber A. McBride, Dominique N. Price, and Pavan Muttil
6. Multifunctionalization of Gold Nanoshells
Sandra W. Bishnoi and Yujen Lin
7. Fabrication of Photothermal Stable Gold Nanosphere/Mesoporous Silica Hybrid Nanoparticle Responsive to Near-Infrared Light
Bei Cheng and Peisheng Xu
8. Engineering Well-Characterized PEG-Coated Nanoparticles for Elucidating Biological Barriers to Drug Delivery
Qi Yang and Samuel K. Lai
9. Piloting Your Nanovehicle to Overcome Biological Barriers
Steven M. Richards and Robert B. Campbell
10. Detecting Sonolysis of Polyethylene Glycol Upon Functionalizing Carbon Nanotubes
Ruhung Wang, Vasanth S. Murali, and Rockford Draper
11. Methods for Generation and Detection of Non-Stationary Vapor Nanobubbles Around Plasmonic Nanoparticles
Ekaterina Y. Lukianova-Hleb and Dmitri O. Lapotko
Part III: Nanotechnology to Study Cancer
12. Force Measurements for Cancer Cells
Vivek Rajasekharan, Varun K.A. Sreenivasan, and Brenda Farrell
13. Fractal Analysis of Cancer Cell Surface
Igor Sokolov and Maxim E. Dokukin
14. Quantitative Evaluation of the Enhanced Permeability and Retention (EPR) Effect
Luisa M. Russell, Charlene M. Dawidczyk, and Peter C. Searson
Part IV: Nanotechnology for Prevention and Detection/Imaging of Cancer
15. Nanotechnology-Based Cancer Vaccines
Aws Alshamsan
16. Designing Multicomponent Nanosystems for Rapid Detection of Circulating Tumor Cells
Shashwat S. Banerjee, Vrushali Khobragade, and Jayant Khandare
17. Fluorescence and Bioluminescence Imaging of Orthotopic B
Автор: Grutzmann Robert, Pilarsky Christian Название: Cancer Gene Profiling: Methods and Protocols ISBN: 1493979973 ISBN-13(EAN): 9781493979974 Издательство: Springer Рейтинг: Цена: 15998.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
1. Factors Affecting the Use of Human Tissues in Biomedical Research: Implications in the Design and Operation of a Biorepository Daniel S. Atherton, Katherine C. Sexton, Dennis Otali, Walter C. Bell, and William E. Grizzle
2. Tissue Microdissection Anja Rabien and Glen Kristiansen
3. Tissue Microarrays Ana-Maria Dancau, Ronald Simon, Martina Mirlacher, and Guido Sauter
4. Gene Expression Analysis in the Age of Mass Sequencing: An Introduction Christian Pilarsky, Lahiri Kanth Nanduri, and Janine Roy
5. Quantitative DNA Methylation in Cancer Ole Ammerpohl, Andrea Haake, Julia Kolarova, and Reiner Siebert
6. Single Nucleotide Polymorphism to Associate Cancer Risk Victoria Shaw, Katie Bullock, and William Greenhalf
7: Exosomes in Cancer Disease Margot Zцller
8: MicroRNAs (miRNAs) Profiling Lu Gao and Feng Jiang
9. Cancer Gene Profiling for Response Prediction B. Michael Ghadimi and Peter Jo
10. Target Gene Discovery for Novel Therapeutic Agents in Cancer Treatment Sanjay Tiwari, Ole Ammerpohl, and Holger Kalthoff
11. Application of Proteomics in Cancer Biomarker Discovery: GeLC-MS/MS Pedro R. Cutillas and Tatjana Crnogorac-Jurcevic
12. Meta-Analysis of Cancer Gene Profiling Data Janine Roy, Christof Winter, and Michael Schroeder
13. Reproducible, Scalable Fusion Gene Detection from RNA-Seq Vladan Arsenijevic and Brandi N. Davis-Dusenbery
14. Transcriptome Sequencing for the Detection of Chimeric Transcripts Hsueh-Ting Chu
Автор: Pamela J. Russell; Paul Jackson; Elizabeth A. King Название: Prostate Cancer Methods and Protocols ISBN: 0896039781 ISBN-13(EAN): 9780896039780 Издательство: Springer Рейтинг: Цена: 25853.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A collection of basic and advanced molecular methods that reveal those markers essential for diagnoses of specific diseases. The techniques range from in vitro methods to in vivo models of prostate cancer, and include new methods for the accurate diagnosis of prostate cancer, and proteome and microarray analyses.
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