Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems, Katdare, Ashok
Автор: Harry G. Brittain Название: Profiles of Drug Substances, Excipients, and Related Methodology, ISBN: 0128033002 ISBN-13(EAN): 9780128033005 Издательство: Elsevier Science Рейтинг: Цена: 28633.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. This organizational structure meets the needs of the pharmaceutical community and allows for the development of a timely vehicle for publishing review materials on this topic. The scope of the Profiles series encompasses review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients.
Автор: Melgardt M. de Villiers; Pornanong Aramwit; Glen S Название: Nanotechnology in Drug Delivery ISBN: 0387776672 ISBN-13(EAN): 9780387776675 Издательство: Springer Рейтинг: Цена: 32652.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Introduces various aspects of the fundamentals of nanotechnology based drug delivery systems and the application of these systems for the delivery of small molecules, proteins, peptides, oligonucleotides and genes. This book describes how these systems overcome challenges offered by biological barriers to drug absorption and drug targeting.
Автор: Ronald Borchardt; Edward Kerns; Michael Hageman; D Название: Optimizing the "Drug-Like " Properties of Leads in Drug Discovery ISBN: 1493950479 ISBN-13(EAN): 9781493950478 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Drug discovery and development is a very complex, costly, and ti- consuming process. Because of the uncertainties associated with predicting the pharmacological effects and the toxicity characteristics of new chemical entities in man, their clinical development is quite prone to failure. In recent years, phar- ceutical companies have come under increasing pressure to introduce new blockbuster drugs into the marketplace more rapidly. Companies have responded to these pressures by introducing new technologies and new strategies to expedite drug discovery and development. Drug discovery and development have traditionally been divided into three separate processes (i. e. , discovery research, preclinical development, and clinical development) that ideally should be integrated both organizationally and functionally. Instead, separate and distinct discovery research, preclinical development, and clinical development divisions were created within many companies during the 1980s and 1990s, Because of their isolation, scientists in the discovery research divisions often were advancing drug candidates into preclinical development that had marginal drug-like properties. For the purpose of this presentation, “drug-like” properties refer to the molecule’s physicochemical, absorption-distribution-metabolism-excretion (ADME), and toxicological properties. Lacking optimal drug-like properties often caused these drug candidates to fail in preclinical or clinical development.
Автор: Michael Kinch Название: A Prescription for Change: The Looming Crisis in Drug Development ISBN: 1469647575 ISBN-13(EAN): 9781469647579 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 4703.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The introduction of new medicines has dramatically improved the quantity and quality of individual and public health while contributing trillions of dollars to the global economy. In spite of these past successes--and indeed because of them--our ability to deliver new medicines may be quickly coming to an end. Moving from the beginning of the twentieth century to the present, A Prescription for Change reveals how changing business strategies combined with scientific hubris have altered the way new medicines are discovered, with dire implications for both health and the economy.
To explain how we have arrived at this pivotal moment, Michael Kinch recounts the history of pharmaceutical and biotechnological advances in the twentieth century. Kinch relates stories of the individuals and organizations that built the modern infrastructure that supports the development of innovative new medicines. He shows that an accelerating cycle of acquisition and downsizing is cannibalizing that infrastructure Kinch demonstrates the dismantling of the pharmaceutical and biotechnological research and development enterprises could also provide opportunities to innovate new models that sustain and expand the introduction of newer and better breakthrough medicines in the years to come.
Автор: Ajit S Narang; Sai H S. Boddu Название: Excipient Applications in Formulation Design and Drug Delivery ISBN: 331937107X ISBN-13(EAN): 9783319371078 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In recent years, emerging trends in the design and development of drug products have indicated ever greater need for integrated characterization of excipients and in-depth understanding of their roles in drug delivery applications.
Описание: Presents comprehensive reviews covering various aspects of drug development and formulation of drugs. This book profiles creatine monohydrate and fexofenadine hydrochloride, as well as five others; and, meets the information needs of the drug development community.
Автор: Harry G. Brittain Название: Profiles of Drug Substances, Excipients, and Related Methodology, ISBN: 0128047844 ISBN-13(EAN): 9780128047842 Издательство: Elsevier Science Рейтинг: Цена: 28633.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. This organizational structure meets the needs of the pharmaceutical community and allows for the development of a timely vehicle for publishing review materials on this topic.
The scope of the Profiles series encompasses review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients.
Profiles of Drug Substances, Excipients, and Related Methodology, Volume 45, presents comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. The series encompasses review articles, with this release focusing on Azilsartan Medoxomil, Piroxicam, Carbetapentane Citrate, Emtricitabine, Etrlotinib, Isotretinoin and Meloxicam.
Автор: Howard Fillit, Jefferson Kinney, Jeffrey Cummings Название: Alzheimer`s Disease Drug Development: Research and Development Ecosystem ISBN: 1108838669 ISBN-13(EAN): 9781108838665 Издательство: Cambridge Academ Рейтинг: Цена: 16474.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Provides a definitive overview of the complex ecosystem facilitating Alzheimer`s Disease drug research and development. Demonstrates a drug`s journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.
Автор: Kenneth L. Andus; Thomas L. Raub Название: Biological Barriers to Protein Delivery ISBN: 1461362563 ISBN-13(EAN): 9781461362562 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In response to the tremendous increase in the number of protein and peptide drugs, this treatise critically reviews transport and metabolism mechanisms relating to the delivery of endogenous and recombinant proteins to mammalian organs, tissues, and cells.
Автор: Lynda M. Sanders; R. Wayne Hendren Название: Protein Delivery ISBN: 0306453592 ISBN-13(EAN): 9780306453595 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Presents case histories and reviews of protein-drug delivery technologies. This book includes an overview of insulin delivery and a discussion of the use of biodegradable microspheres.
Описание: * Greatly expanded and completely revised * Covers now not only drug application of biopharmaceuticals but also their use in diagnostics and vaccine development. * Includes material on quality control, safety issue, patent and legal regulations .
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
