Methods and Applications of Statistics in Clinical Trials, Volume 2 - Planning, Analysis, and Inferential Methods, Balakrishnan
Автор: Field, Andy Miles, Jeremy Field, Zoe Название: Discovering statistics using r ISBN: 1446289133 ISBN-13(EAN): 9781446289136 Издательство: Sage Publications Рейтинг: Цена: 9504.00 р. Наличие на складе: Нет в наличии.
Описание: The R version of Andy Field`s hugely popular Discovering Statistics Using SPSS takes students on a journey of statistical discovery using the freeware R - a free, flexible and dynamically changing software tool for data analysis that is becoming increasingly popular across the social and behavioural sciences.
Автор: Lawrence M. Friedman; Curt D. Furberg; David L. De Название: Fundamentals of Clinical Trials ISBN: 3319307738 ISBN-13(EAN): 9783319307732 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Поставка под заказ.
Описание: This is the fifth edition of a very successful textbook on clinical trials methodology, written by recognized leaders who have long and extensive experience in all areas of clinical trials. The three authors of the first four editions have been joined by two others who add great expertise. A chapter on regulatory issues has been included and the chapter on data monitoring has been split into two and expanded. Many contemporary clinical trial examples have been added. There is much new material on adverse events, adherence, issues in analysis, electronic data, data sharing and international trials. This book is intended for the clinical researcher who is interested in designing a clinical trial and developing a protocol. It is also of value to researchers and practitioners who must critically evaluate the literature of published clinical trials and assess the merits of each trial and the implications for the care and treatment of patients. The authors use numerous examples of published clinical trials to illustrate the fundamentals. The text is organized sequentially from defining the question to trial closeout. One chapter is devoted to each of the critical areas to aid the clinical trial researcher. These areas include pre-specifying the scientific questions to be tested and appropriate outcome measures, determining the organizational structure, estimating an adequate sample size, specifying the randomization procedure, implementing the intervention and visit schedules for participant evaluation, establishing an interim data and safety monitoring plan, detailing the final analysis plan and reporting the trial results according to the pre-specified objectives. Although a basic introductory statistics course is helpful in maximizing the benefit of this book, a researcher or practitioner with limited statistical background would still find most if not all the chapters understandable and helpful. While the technical material has been kept to a minimum, the statistician may still find the principles and fundamentals presented in this text useful.
Автор: Gates, Kathleen, Название: Intensive longitudinal analysis of human processes / ISBN: 1482230593 ISBN-13(EAN): 9781482230598 Издательство: Taylor&Francis Рейтинг: Цена: 14545.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on a span of statistical topics relevant to researchers who seek to conduct person-specific analysis of human data. The primary audience are students and researchers in psychometrics, quantitative psychology, psychophysiology and neurocognition. This book can be used for both teaching and research.
Автор: Kimmo Vehkalahti , Brian S. Everitt Название: Multivariate Analysis for the Behavioral Sciences, Second Edition ISBN: 0815385153 ISBN-13(EAN): 9780815385158 Издательство: Taylor&Francis Рейтинг: Цена: 13014.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Multivariate Analysis for the Behavioral Sciences, Second Edition is designed to show how a variety of statistical methods can be used to analyse data collected by psychologists and other behavioral scientists.
A practical introduction to epidemiology, biostatistics, and research methodology for the whole health care community
This comprehensive text, which has been extensively revised with new material and additional topics, utilizes a practical slant to introduce health professionals and students to epidemiology, biostatistics, and research methodology. It draws examples from a wide range of topics, covering all of the main contemporary health research methods, including survival analysis, Cox regression, and systematic reviews and meta-analysis--the explanation of which go beyond introductory concepts. This second edition of Quantitative Methods for Health Research: A Practical Interactive Guide to Epidemiology and Statistics also helps develop critical skills that will prepare students to move on to more advanced and specialized methods.
A clear distinction is made between knowledge and concepts that all students should ensure they understand, and those that can be pursued further by those who wish to do so. Self-assessment exercises throughout the text help students explore and reflect on their understanding. A program of practical exercises in SPSS (using a prepared data set) helps to consolidate the theory and develop skills and confidence in data handling, analysis, and interpretation. Highlights of the book include:
Combining epidemiology and bio-statistics to demonstrate the relevance and strength of statistical methods
Emphasis on the interpretation of statistics using examples from a variety of public health and health care situations to stress relevance and application
Use of concepts related to examples of published research to show the application of methods and balance between ideals and the realities of research in practice
Integration of practical data analysis exercises to develop skills and confidence
Supplementation by a student companion website which provides guidance on data handling in SPSS and study data sets as referred to in the text
Quantitative Methods for Health Research, Second Edition is a practical learning resource for students, practitioners and researchers in public health, health care and related disciplines, providing both a course book and a useful introductory reference.
Описание: This comprehensive book features both new and established material on the key statistical principles and concepts for designing modern-day clinical trials, such as hazard ratio, flexible designs, confounding, covariates, missing data, and longitudinal data.
Автор: Takashi Daimon; Akihiro Hirakawa; Shigeyuki Matsui Название: An Introduction to Dose-Finding Methods in Early Phase Clinical Trials ISBN: 4431555846 ISBN-13(EAN): 9784431555841 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Included are rule-based and model-based designs, such as 3 + 3 designs, accelerated titration designs, toxicity probability interval designs, continual reassessment method and related designs, and escalation overdose control designs.
Автор: Jones Название: Design and Analysis of Cross-Over Trials, Third Edition ISBN: 1439861420 ISBN-13(EAN): 9781439861424 Издательство: Taylor&Francis Рейтинг: Цена: 16843.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Design and Analysis of Cross-Over Trials is concerned with a specific kind of comparative trial known as the cross-over trial, in which subjects receive different sequences of treatments. Such trials are widely used in clinical and medical research, and in other diverse areas such as veterinary science, psychology, sports science, and agriculture.
The first edition of this book was the first to be wholly devoted to the subject. The second edition was revised to mirror growth and development in areas where the design remained in widespread use and new areas where it had grown in importance. This new Third Edition
Contains seven new chapters written in the form of short case studies that address re-estimating sample size when testing for average bioequivalence, fitting a nonlinear dose response function, estimating a dose to take forward from phase two to phase three, establishing proof of concept, and recalculating the sample size using conditional power
Employs the R package Crossover, speciallycreated to accompany the book and provide a graphical user interface for locating designs in a large catalog and for searching for new designs
Includes updates regarding the use of period baselines and the analysis of data from very small trials
Reflects the availability of new procedures in SAS, particularly proc glimmix
Presents the SAS procedure proc mcmc as an alternative to WinBUGS for Bayesian analysis
Complete with real data and downloadable SAS code, Design and Analysis of Cross-Over Trials, Third Edition provides a practical understanding of the latest methods along with the necessary tools for implementation.
Описание: This book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials. Blinded sample size recalculation procedures for internal pilot study designs are considered, as well as methods for sample size reassessment in adaptive designs that use unblinded data from interim analyses.
Автор: Shih, Weichung Joe (rutgers University School Of Public Health, Piscataway, New Jersey, Usa) Aisner, Joseph (rutgers University Robert Wood Johnson Me Название: Statistical design, monitoring, and analysis of clinical trials ISBN: 0367772442 ISBN-13(EAN): 9780367772444 Издательство: Taylor&Francis Рейтинг: Цена: 12707.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book concentrates on the biostatistics component of clinical trials. This new, second edition is updated throughout and includes three new chapters. This text reflects the academic research, commercial development, and public health aspects of clinical trials.
Описание: Upgraded to reflect the latest research and software applications on the topic, this new edition continues to provide a comprehensive introduction to the statistical methods for analyzing survival data.
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