Gap Junction Protocols, Mathieu Vinken; Scott R. Johnstone
Автор: Zachariou Michael Название: Affinity Chromatography / Methods and Protocols ISBN: 1588296598 ISBN-13(EAN): 9781588296597 Издательство: Springer Рейтинг: Цена: 2000.00 р. Наличие на складе: Есть (2 шт.) Описание: Thirty-eight years after its introduction, affinity chromatography remains a key tool in th armory of separation techniques available to separation and interaction scientists. Expanded and updated from the first edition, this second edition volume aims to provide the beginner with the practical knowledge needed to develop affinity separations suitable for a variety of applications relevant to the post-genomic era.
Автор: Connell Joe Название: RT-PCR Protocols ISBN: 0896038750 ISBN-13(EAN): 9780896038752 Издательство: Springer Цена: 13270.00 р. Наличие на складе: Поставка под заказ.
Описание: A panel of highly regarded molecular biologists and clinical researchers describe in detail their most novel, useful, and interesting RT-PCR applications. Here the newcomer will find readily reproducible protocols for highly sensitive detection and quantification of gene expression, the in situ localization of gene expression in tissue, and the cloning of genes, as well as for analyzing T-cell clones and the differential expression of genes. For the expert seeking to extend the usefulness of RT-PCR, there are user-friendly applications that complement the latest technological advances, including laser-capture microdissection (LCM), real-time and quantitative PCR, microarray technology, cDNA cloning, and antibody engineering.
Автор: Martin Tracey A Название: Tight Junctions in Cancer Metastasis ISBN: 9400760272 ISBN-13(EAN): 9789400760271 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book summarizes current knowledge of tight junctions and their role in cancer and cancer metastasis. Coverage includes fundamental changes in tight junctions in the process of cancer development and the importance of cellular structure in drug therapy.
Автор: Lorenza Gonz?lez-Mariscal Название: Tight Junctions ISBN: 1441941150 ISBN-13(EAN): 9781441941152 Издательство: Springer Цена: 27951.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: ight junctions (TJs) are cell-ceil adhesion belts that encircle epithelial and endothelial cells at the limit between the apical and the lateral Tmembrane. These junctions are crucial for the establishment of separate compartments in multicellular organisms and for the exchange of substances between the internal milieu and the external environment. The perception of TJs has changed over the years. From being regarded as static paracellular seals, they have come to be perceived as dynamic structures that adjust their morphol- ogy and function in response to physiological, pharmacological and pathologi- cal challenges. The roles that TJs play in epithelial and endothelial cells has also widened, and nowadays this structure is regarded not only as a fence that limits within the membrane, the movement of proteins and lipids between the apical and basolateral membranes, or as a gate that regulates in a size and charge selec- tive manner the transit of ion and molecules through the paracellular pathway, but also as a structure integrated by molecules that participate in the control of cell proliferation. These observations highlight the importance of understand- ing TJ physiology in order to develop effective strategies for the treatment of pathological conditions such as cancer and autoimmune diseases. This broader perception of TJs is reflected in all the chapters of the book and has been attained thanks to the identification in recent years of a wide array of proteins that constitute TJs in epithelial and endothelial cells as well as in central nervous system myelin.
Автор: A.W. Robards; W.J. Lucas; John D. Pitts; H.J. Jong Название: Parallels in Cell to Cell Junctions in Plants and Animals ISBN: 3642839738 ISBN-13(EAN): 9783642839733 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the NATO Advanced Research Workshop on Parallels in Cell to Cell Communication in Plants and Animals held in York, England, July 2-7, 1989
Описание: Cell-cell adhesion is fundamental for the development and homeostasis of animal tissues and organs. * How do cadherins and catenins interact to assemble AJs and mediate adhesion? * How do AJs interface with other cellular machinery to couple adhesion with the whole cell? * How do AJs affect cell behaviour and multicellular development?
Автор: Tracey A. Martin; Wen G. Jiang Название: Tight Junctions in Cancer Metastasis ISBN: 9400798067 ISBN-13(EAN): 9789400798069 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book summarizes current knowledge of tight junctions and their role in cancer and cancer metastasis. Coverage includes fundamental changes in tight junctions in the process of cancer development and the importance of cellular structure in drug therapy.
Автор: Dr. Mahboob Ul Hussain Название: Connexins: The Gap Junction Proteins ISBN: 813221918X ISBN-13(EAN): 9788132219187 Издательство: Springer Рейтинг: Цена: 7685.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Gap-junction proteins, connexins are important cellular entities that regulate various facets of cellular physiology. The connexins constitute large family of proteins. The present book provides basic overview about various aspects of connexin proteins. The book has tried to touch the fundamental aspects of connexin family. This book will be useful to broad audience that includes under-and post-graduate students, research scholars, clinicians, etc. The reference section at the end of the book will be helpful for those who seek to know deeper details about this family of proteins.
Автор: David C. Spray; Rolf Dermietzel Название: Gap Junctions in the Nervous System ISBN: 3662219379 ISBN-13(EAN): 9783662219379 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Название: Tight Junctions Second Edition ISBN: 0849323835 ISBN-13(EAN): 9780849323836 Издательство: Taylor&Francis Рейтинг: Цена: 30624.00 р. Наличие на складе: Поставка под заказ.
Описание: As the first detailed overview of the subject, Tight Junctions brought together diverse perspectives from leading investigators to provide a multidisciplinary overview of the field. Since its publication in 1992, there has been an explosion of information about tight junctions, particularly in the area of molecular structure, cl and molecular biology, genetics and physiology. The field has advanced so fast and so far that it influences many areas of biology and now has practical implications for pharmacology of drug delivery and understanding a wide range of diseases altering epithelial permeability.
Описание: This book details the latest aspects of the culture of neural cells and explains the practical and theoretical considerations of the techniques involved. It features step-by-step, readily reproducible laboratory protocols and expert implementation advice.
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