Автор: Cornelis Murre Название: Epigenetic Regulation of Lymphocyte Development ISBN: 3642447678 ISBN-13(EAN): 9783642447679 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The studies described in this volume serve as a starting point to familiarize one self with the multifarious differences in epigenetic designs that orchestrate the progression of developing blood cells. They also may serve as a general paradigm for the mechanisms that underpin the control of eukaryotic gene expression.
Описание: This volume reviews research in the field of B cell development and differentiation. The contents focus on the biochemical pathways regulating B cell biology and the role of signal transduction processes in regulating various aspects of B cell function, development and differentiation.
Автор: Sudhir Gupta; Frederick W. Alt; Max D. Cooper; Fri Название: Mechanisms of Lymphocyte Activation and Immune Regulation XI ISBN: 1441942831 ISBN-13(EAN): 9781441942838 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In recent years, major developments have increased understanding of various genetic and epigenetic regulatory processes that are critical for the generation of B cell repertoires.
Автор: Sudhir Gupta; William E. Paul; Anthony DeFranco; R Название: Mechanisms of Lymphocyte Activation and Immune Regulation V ISBN: 0306448971 ISBN-13(EAN): 9780306448973 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: It includes a contemporary assessment of B cell antigen receptor structures, and discussion of the role of Ig-a/lg-B polypeptides in linking the antigen receptor to intracellular signal transduction pathways.
Автор: Sudhir Gupta; William E. Paul; Ralph Steinman Название: Mechanisms of Lymphocyte Activation and Immune Regulation X ISBN: 1441937005 ISBN-13(EAN): 9781441937001 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume is edited by Dr. Sudhir Gupta, internationally recognized expert in Immunology, Professor of Medicine, Pathology, Microbiology and Molecular Genetics. Topics include toll receptors, dendritic cells, NK cells, and complement receptors.
Автор: Harinder Singh; Rudolf Grosschedl Название: Molecular Analysis of B Lymphocyte Development and Activation ISBN: 3642421881 ISBN-13(EAN): 9783642421884 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Gene Regulatory Networks Orchestrating B Cell Fate Specification, Commitment, and Differentiation.- Helix-Loop-Helix Proteins in Lymphocyte Lineage Determination.- Ikaros-Family Proteins: In Search of Molecular Functions During Lymphocyte Development.- Biochemistry of V(D)J Recombination.- The Pre-B Cell Receptor in B Cell Development: Recent Advances, Persistent Questions and Conserved Mechanisms.- Transcriptional Control of B Cell Activation.-Expression of MHC II Genes.- Class Switch Recombination: An Emerging Mechanism.- Blimp-1, Immunoglobulin Secretion, and the Switch to Plasma Cells.- Wnt Signaling in Lymphopoiesis.- Subject Index
Описание: This volume provides a review of current research in the field of B cell development and differentiation with particular emphasis on signal transduction processes.
Описание: Provides a review of research in the field of B cell development and differentiation with particular emphasis on signal transduction processes. This book focuses on the biochemical pathways which regulate B cell biology and the role of signal transduction processes in regulating various aspects of B cell function, development and differentiation.
Описание: The immune system must maintain a balance between the deletion of harmful self-reactive B cells and the generation of a diverse rep- ertoire of B cells that has the ability to recognize an almost un- limited array of foreign antigens.
Автор: Sudhir Gupta; J. John Cohen Название: Mechanisms of Lymphocyte Activation and Immune Regulation VI ISBN: 0306454831 ISBN-13(EAN): 9780306454837 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Sixth International Conference held in Newport Beach, California, Feb 2-4, 1996
Автор: Constantine Tsoukas Название: Lymphocyte Signal Transduction ISBN: 1489990135 ISBN-13(EAN): 9781489990136 Издательство: Springer Рейтинг: Цена: 34937.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Signal transduction through leukocyte receptors involves a variety of signaling molecules including kinases, phosphatases, adaptor proteins, small GTPases GTP exchange factors, membrane phospholipids as well as others. These signal transducers, regulated by inter- and intra-molecular interactions, as well as by various post-translational modifications, lead to the activation of transcription factors that mediate cellular differentiation and growth, effector cell functions, and apoptotic cell death. Several investigators from various parts of the world convened at the 3rd Lymphocyte Signal Transduction Workshop in Crete, Greece from May 27 to June 1, 2005 to discuss their most recent findings in leukocyte signaling. This volume represents a collection of topics discussed during the conference.
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