Автор: Karp Daniel D Название: Handbook of Targeted Cancer Therapy and Immunotherapy ISBN: 1496389131 ISBN-13(EAN): 9781496389138 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 7979.00 р. Наличие на складе: Поставка под заказ.
Описание: A must-have resource for oncologists, researchers, and other cancer care professionals! This comprehensive yet concise reference includes clinical trial results of more than 190 targeted therapy and immunotherapy agents. Immunotherapy trial results expanded Tumor immunology section added Recent landmark trial results incorporated FDA approvals highlighted Approach clinical challenges from any direction. Chapters organized by tumor type, pathway, and drug name. Find information quickly and easily, using a color-coded, intuitive format. Small enough to fit in your lab coat pocket. Or, download the eBook to your smartphone or other device for even more convenient referencing. Enhance Your eBook Reading Experience: Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.
Описание: Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy, Second Edition, provides a comprehensive overview of the molecular methodologies in the neuro-oncology field. There have been profound changes in the landscape of approaches to brain tumor therapy since the first edition—mainly in the areas of molecular biology and molecular therapeutics, as well as in the maturation of immunotherapy approaches (e.g., vaccines). This updated edition has a new, primary focus on multidisciplinary molecular methods, and is broadened to include the latest cutting-edge molecular biology, therapeutics, immunobiology and immunotherapy approaches. . As the first comprehensive book to address the molecular research into these concepts, users will find it to be an invaluable resource on the topics discussed.
Описание: This comprehensive reference source will benefit all transplant specialists working with pharmacologic and biologic agents that modulate the immune system.
Автор: Sandip Pravin Patel; Razelle Kurzrock Название: Early Phase Cancer Immunotherapy ISBN: 3319876287 ISBN-13(EAN): 9783319876283 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Поставка под заказ.
Описание: This volume, a state-of-the-art review of early phase clinical trials for cancer immunotherapy, discusses biomarker selection, combinatorial strategies and their safety or toxicity, determination of Phase 2 dosing, endpoints in the setting of radiographic pseudoprogression, histology selection, and novel immunotherapeutics as they relate to early phase cancer immunotherapy.
Автор: Samuel G. Katz; Peter M. Rabinovich Название: Cell Reprogramming for Immunotherapy ISBN: 1071602020 ISBN-13(EAN): 9781071602027 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume details key protocols for developing strategies in immunotherapy. Chapters guide the readers through protocols related to various DNA, RNA and protein methods to reprogram the immune system, immune cells, analyzing the effect of the reprogrammed cells, and key methods to consider and analyze patients enrolled in clinical trials with novel immunotherapy regimens. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cell Reprogramming for Immunotherapy: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Автор: William E. Schiesser Название: Spatiotemporal Modeling of Cancer Immunotherapy ISBN: 3030176355 ISBN-13(EAN): 9783030176358 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The focus of this book is a detailed discussion of a dual cancer vaccine (CV)-immune checkpoint inhibitor (ICI) mathematical model formulated as a system of partial differential equations (PDEs) defining the spatiotemporal distribution of cells and biochemicals during tumor growth.A computer implementation of the model is discussed in detail for the quantitative evaluation of CV-ICI therapy. The coding (programming) consists of a series of routines in R, a quality, open-source scientific computing system that is readily available from the internet. The routines are based on the method of lines (MOL), a general PDE algorithm that can be executed on modest computers within the basic R system. The reader can download and use the routines to confirm the model solutions reported in the book, then experiment with the model by varying the parameters and modifying/extending the equations, and even studying alternative models with the PDE methodology demonstrated by the CV-ICI model.Spatiotemporal Modeling of Cancer Immunotherapy: Partial Differential Equation Analysis in R facilitates the use of the model, and more generally, computer- based analysis of cancer immunotherapy mathematical models, as a step toward the development and quantitative evaluation of the immunotherapy approach to the treatment of cancer.To download the R routines, please visit: http://www.lehigh.edu/~wes1/ci_download
Автор: Hironori Nakagami Название: Therapeutic Vaccines as Novel Immunotherapy ISBN: 9813296275 ISBN-13(EAN): 9789813296275 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Поставка под заказ.
Описание: This book offers an excellent introduction to the use of novel therapeutic vaccines for common diseases based on their ability to induce antibody production. While the role of vaccines in the treatment of infectious diseases and cancer is well known, vaccines have also recently been developed for a variety of other conditions, including Alzheimer’s disease, hypertension, diabetes, and spondyloarthritis. These therapeutic advances are fully and clearly documented by acknowledged experts in the field, who explain the relevant biology and highlight the challenges involved in deploying this treatment approach effectively and safely. In addition, recent progress in the construction and delivery of DNA vaccines is documented, and the process of developing new peptide vaccines is explored in depth. While the book will be particularly valuable for researchers and scholars interested in immunotherapy, it will also appeal to clinicians seeking effective new medicines to treat patients suffering from chronic diseases.
Автор: R.J.A. van Moorselaar; Frans M.J. Debruyne; Ronald Название: Immunotherapy of Renal Cell Carcinoma ISBN: 3540528350 ISBN-13(EAN): 9783540528357 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Автор: Paul Koldovsky; Ursula Koldovsky; Lutwin Beck; Kar Название: Lymphocytes in Immunotherapy of Cancer ISBN: 3540504575 ISBN-13(EAN): 9783540504573 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Vaccination has been investigated clinically for its po- tential to prevent cancer [1], and clinical research into the cure of cancer has included active immunization [2], nonspecific stimulation of defense mechanisms [3], and transfer of passive immunity by cells [4] or by antibodies [5].
Автор: Aung Naing; Joud Hajjar Название: Immunotherapy ISBN: 303037856X ISBN-13(EAN): 9783030378561 Издательство: Springer Рейтинг: Цена: 11179.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The second edition of Immunotherapy is an updated overview of immuno-oncology in acute myleloid leukemia, non-small cell lung cancer and melanoma, showcasing advances in the management of cancer broadly classified as hematological malignancies and solid tumors. Though the spectrum of clinical activity and duration of response seen with these agents is promising, objective response is limited to a subset of patients and is often associated with distinct side effects that are potentially life-threatening. With increasing use of checkpoint inhibitors as standard of care and in clinical trials, the burden of immune-related adverse events will undoubtedly increase. Given these limitations and increase in health care costs associated with such therapies, it is essential to identify patients who are likely to respond to immunotherapy and those who are at a risk for developing treatment-related side effects. This new edition will inform readers on the latest in biomarker development to identify patients who are more likely to respond, and strategies to overcome the challenges of immune-related adverse events. In addition, the authors recognize that including the missing patient voice in clinical trials and longitudinal assessment of symptom reports may help to identify early indicators of response or toxicity. Thus, the book includes a chapter on patient-reported outcomes in patients treated with immunotherapies. The authors believe that acquiring this knowledge will help health care professionals make informed treatment decisions.Edited by two renowned experts in the field, the book’s chapters are written by a diverse cast of experts conducting cutting-edge research, providing the reader with the most up-to-date science.
Автор: Roberto Ceriani Название: Breast Cancer Immunodiagnosis and Immunotherapy ISBN: 1475712987 ISBN-13(EAN): 9781475712988 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A practical reference to managing side effects associated with FDA-approved cancer immunotherapy drugs. Part One contains chapter-based overviews of immune checkpoint inhibitors in the clinic. Part Two is structured by common and uncommon toxicities that affect major organ sites throughout the body.
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