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Protein Function Prediction: Methods and Protocols, Kihara Daisuke


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Автор: Kihara Daisuke
Название:  Protein Function Prediction: Methods and Protocols
ISBN: 9781493983681
Издательство: Springer
Классификация:
ISBN-10: 1493983687
Обложка/Формат: Paperback
Страницы: 239
Вес: 0.36 кг.
Дата издания: 17.07.2018
Серия: Methods in molecular biology
Язык: English
Издание: Softcover reprint of
Иллюстрации: 71 illustrations, color; 11 illustrations, black and white; x, 239 p. 82 illus., 71 illus. in color.
Размер: 23.39 x 15.60 x 1.35 cm
Читательская аудитория: General (us: trade)
Подзаголовок: Methods and protocols
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание: Preface...
Table of Contents...
Contributing Authors...

1. Using PFP and ESG Protein Function Prediction Web Servers
Qing Wei, Joshua McGraw, Ishita Khan, and Daisuke Kihara

2. GHOSTX: A Fast Sequence Homology Search Tool for Functional Annotation of Metagenomic Data
Shuji Suzuki, Takashi Ishida, Masahito Ohue, Masanori Kakuta, and Yutaka Akiyama

3. From Gene Annotation to Function Prediction for Metagenomics
Fatemeh Sharifi and Yuzhen Ye

4. An Agile Functional Analysis of Metagenomic Data using SUPER-FOCUS
Genivaldo Gueiros Z. Silva, Fabyano A. C. Lopes, and Robert A. Edwards

5. MPFit: Computational Tool for Predicting Moonlighting Proteins
Ishita Khan, Joshua McGraw, and Daisuke Kihara

6. Predicting Secretory Proteins with SignalP
Henrik Nielsen

7. The ProFunc Function Prediction Server
Roman A. Laskowski

8. G-LoSA for Prediction of Protein-Ligand Binding Sites and Structures
Hui Sun Lee and Wonpil Im

9. Local Alignment of Ligand Binding Sites in Proteins for Polypharmacology and Drug Repositioning
Michal Brylinski

10. WATsite2.0 with PyMOL Plugin: Hydration Site Prediction and Visualization
Ying Yang, Bingjie Hu, and Markus A. Lill

11. Enzyme Annotation and Metabolic Reconstruction Using KEGG
Minoru Kanehisa

12. Ortholog Identification and Comparative Analysis of Microbial Genomes using MBGD and RECOG
Ikuo Uchiyama

13. Exploring Protein Function Using the Saccharomyces Genome Database
Edith D. Wong

14. Network-Based Gene Function Prediction in Mouse and Other Model Vertebrates using MouseNet Server
Eiru Kim and Insuk Lee

15. The FANTOM5 Computation Ecosystem: Genomic Information Hub for Promoters and Active Enhancers
Imad Abugessaisa, Shuhei Noguchi, Piero Carninci, and Takeya Kasukawa

16. Multi-Algorithm Particle Simulations with Spatiocyte
Satya N. V. Arjunan and Koichi Takahashi



Computational Methods for Protein Structure Prediction and Modeling

Автор: Ying Xu; Dong Xu; Jie Liang
Название: Computational Methods for Protein Structure Prediction and Modeling
ISBN: 1441922067 ISBN-13(EAN): 9781441922069
Издательство: Springer
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Цена: 26120.00 р.
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Описание: Volume Two of this two-volume sequence presents a comprehensive overview of protein structure prediction methods and includes protein threading, De novo methods, applications to membrane proteins and protein complexes, structure-based drug design, as well as structure prediction as a systems problem.

Protein Synthesis: Methods and Protocols

Автор: Bhupendra Pushkar
Название: Protein Synthesis: Methods and Protocols
ISBN: 1774077035 ISBN-13(EAN): 9781774077030
Издательство: Mare Nostrum (Eurospan)
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Цена: 22730.00 р.
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Описание: Takes readers through the various ways in which proteins are synthesized and then further used for other applications. The book throws light on chemical reactions taking place in the process, and lays down different kinds of methods and the procedures that are followed in protein synthesis.

Membrane Protein Structure and Function Characterization: Methods and Protocols

Автор: Lacapere Jean-Jacques
Название: Membrane Protein Structure and Function Characterization: Methods and Protocols
ISBN: 1493983997 ISBN-13(EAN): 9781493983995
Издательство: Springer
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Цена: 19564.00 р.
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Описание: In this present volume, different approaches are detailed to produce membrane proteins, purify them, study their function, determine their structure, and model them in membrane.

New Approaches of Protein Function Prediction from Protein Intera

Автор: Hou, Jingyu
Название: New Approaches of Protein Function Prediction from Protein Intera
ISBN: 0128098147 ISBN-13(EAN): 9780128098141
Издательство: Elsevier Science
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Цена: 11706.00 р.
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Описание:

New Approaches of Protein Function Prediction from Protein Interaction Networks contains the critical aspects of PPI network based protein function prediction, including semantically assessing the reliability of PPI data, measuring the functional similarity between proteins, dynamically selecting prediction domains, predicting functions, and establishing corresponding prediction frameworks.

Functional annotation of proteins is vital to biological and clinical research and other applications due to the important roles proteins play in various biological processes. Although the functions of some proteins have been annotated via biological experiments, there are still many proteins whose functions are yet to be annotated due to the limitations of existing methods and the high cost of experiments. To overcome experimental limitations, this book helps users understand the computational approaches that have been rapidly developed for protein function prediction.

Protein Function Prediction

Автор: Daisuke Kihara
Название: Protein Function Prediction
ISBN: 1493970135 ISBN-13(EAN): 9781493970131
Издательство: Springer
Рейтинг:
Цена: 19564.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Preface...
Table of Contents...
Contributing Authors...

1. Using PFP and ESG Protein Function Prediction Web Servers
Qing Wei, Joshua McGraw, Ishita Khan, and Daisuke Kihara

2. GHOSTX: A Fast Sequence Homology Search Tool for Functional Annotation of Metagenomic Data
Shuji Suzuki, Takashi Ishida, Masahito Ohue, Masanori Kakuta, and Yutaka Akiyama

3. From Gene Annotation to Function Prediction for Metagenomics
Fatemeh Sharifi and Yuzhen Ye

4. An Agile Functional Analysis of Metagenomic Data using SUPER-FOCUS
Genivaldo Gueiros Z. Silva, Fabyano A. C. Lopes, and Robert A. Edwards

5. MPFit: Computational Tool for Predicting Moonlighting Proteins
Ishita Khan, Joshua McGraw, and Daisuke Kihara

6. Predicting Secretory Proteins with SignalP
Henrik Nielsen

7. The ProFunc Function Prediction Server
Roman A. Laskowski

8. G-LoSA for Prediction of Protein-Ligand Binding Sites and Structures
Hui Sun Lee and Wonpil Im

9. Local Alignment of Ligand Binding Sites in Proteins for Polypharmacology and Drug Repositioning
Michal Brylinski

10. WATsite2.0 with PyMOL Plugin: Hydration Site Prediction and Visualization
Ying Yang, Bingjie Hu, and Markus A. Lill

11. Enzyme Annotation and Metabolic Reconstruction Using KEGG
Minoru Kanehisa

12. Ortholog Identification and Comparative Analysis of Microbial Genomes using MBGD and RECOG
Ikuo Uchiyama

13. Exploring Protein Function Using the Saccharomyces Genome Database
Edith D. Wong

14. Network-Based Gene Function Prediction in Mouse and Other Model Vertebrates using MouseNet Server
Eiru Kim and Insuk Lee

15. The FANTOM5 Computation Ecosystem: Genomic Information Hub for Promoters and Active Enhancers
Imad Abugessaisa, Shuhei Noguchi, Piero Carninci, and Takeya Kasukawa

16. Multi-Algorithm Particle Simulations with Spatiocyte
Satya N. V. Arjunan and Koichi Takahashi

Protein Function Prediction for Omics Era

Автор: Daisuke Kihara
Название: Protein Function Prediction for Omics Era
ISBN: 9400799640 ISBN-13(EAN): 9789400799646
Издательство: Springer
Рейтинг:
Цена: 28732.00 р.
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Описание: This book examines the emerging development of computational gene function prediction methods, which are targeted to analyze large scale data, and also those which use such omics data as additional source of function prediction.

Computational Methods for Protein Structure Prediction and Modeling

Автор: Ying Xu; Dong Xu; Jie Liang
Название: Computational Methods for Protein Structure Prediction and Modeling
ISBN: 1441922059 ISBN-13(EAN): 9781441922052
Издательство: Springer
Рейтинг:
Цена: 26120.00 р.
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Описание: Volume One of this two-volume sequence focuses on the basic characterization of known protein structures, and structure prediction from protein sequence information. Eleven chapters survey of the field, covering key topics in modeling, force fields, classification, computational methods, and structure prediction.

Hdac/Hat Function Assessment and Inhibitor Development: Methods and Protocols

Автор: Krдmer Oliver H.
Название: Hdac/Hat Function Assessment and Inhibitor Development: Methods and Protocols
ISBN: 1493982265 ISBN-13(EAN): 9781493982264
Издательство: Springer
Рейтинг:
Цена: 15372.00 р.
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Описание: This detailed collection covers how the biological functions of histone deacetylases (HDACs) and histone acetyltransferases (HATs) can be detected in various experimental settings, both in vivo and in vitro.

Protein Supersecondary Structures: Methods and Protocols

Автор: Kister Alexander E.
Название: Protein Supersecondary Structures: Methods and Protocols
ISBN: 1493991604 ISBN-13(EAN): 9781493991600
Издательство: Springer
Рейтинг:
Цена: 20962.00 р.
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Описание:

This second edition volume expands on the previous edition with an update on the latest developments in the field and new techniques used to study secondary and supersecondary structures (SSS) in proteins. Chapters in this book discuss topics such as sequence and structural features of different SSS elements; software used for the automatic annotation of secondary structure elements in proteins; the new developments in secondary and SSS prediction and the modern approaches for energy landscape calculation; protein misfolding and amyloid structural formation; analysis of ‘transformer proteins’; discovery of the structure of the hydrophobic nucleus; and discussions of the main principles of protein structures formation. The contributing authors of the volume are the eminent experts in the field of protein research and bioinformatics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and authoritative, Protein Supersecondary Structures: Methods and Protocols, Second Edition is a valuable resource for researchers who are interested in learning more about the relationship between amino acids sequences and protein structures, the evolution of proteins and the dynamics of protein formation.
Protein Chromatography: Methods and Protocols

Автор: Walls Dermot, Loughran Sinйad T.
Название: Protein Chromatography: Methods and Protocols
ISBN: 1493961292 ISBN-13(EAN): 9781493961290
Издательство: Springer
Рейтинг:
Цена: 15372.00 р.
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Описание: A prerequisite for elucidating the structure and function of any protein is the prior purification of that protein. This necessity has led to the development of many purification schemes and chromatographic methods for the isolation of native proteins from complex sources. In Protein Chromatography: Methods and Protocols, leading researchers present clear protocol-style chapters that are suitable for newcomers and experts alike. The book opens with vital topics in protein biochemistry, addressing such areas as protein stability and storage, avoiding proteolysis during chromatography, protein quantitation methods including immuno-qPCR, and the contrasting challenges that microfluidics and scale-up production pose to the investigator, and then it segues into key methods involving the generation and purification of recombinant proteins through recombinant antibody production and the tagging of proteins, amongst other means, as well as many variations on classic techniques such as ion-exchange and immunoaffinity chromatography. Written in the highly successful Methods in Molecular Biology™ series format, protocols chapters include introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Protein Chromatography: Methods and Protocols will greatly aid scientists in establishing these essential techniques in their own laboratories and furthering our understanding of the many imperative functions of proteins.

Unconventional Protein Secretion: Methods and Protocols

Автор: Pompa Andrea, De Marchis Francesca
Название: Unconventional Protein Secretion: Methods and Protocols
ISBN: 1493981447 ISBN-13(EAN): 9781493981441
Издательство: Springer
Рейтинг:
Цена: 6986.00 р.
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Описание:

Part I: Background

1. ER to Golgi Dependent Protein Secretion: The Conventional Pathway

Corrado Viotti

2. Unconventional Protein Secretion in Animal Cells

Fanny Ng and Bor Luen Tang

3. Unconventional Protein Secretion in Plants

Destiny J. Davis, Byung-Ho Kang, Angelo S. Heringer, Thomas E. Wilkop, and Georgia Drakakaki

Part II: UPS Contemplates Multidisciplinary Approaches for Plants

4. Chemical Secretory Pathway Modulation in Plant Protoplasts

Francesca De Marchis, Andrea Pompa, and Michele Bellucci

5. From Cytosol to the Apoplast: The Hygromycin Phosphotransferase (HYGR) Model in Arabidopsis

Haiyan Zhang and Jinjin Li

6. Following the Time-Course of Post-Pollination Events by Transmission Electron Microscopy (TEM): Buildup of Exosome-Like Structures with Compatible Pollinations

Darya Safavian, Jennifer Doucet, and Daphne R. Goring

Part III: UPS Contemplates Multidisciplinary Approaches for Animals and Fungi

7. Investigating Alternative Transport of Integral Plasma Membrane Proteins from the ER to the Golgi: Lessons from the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)

Margarida D. Amaral, Carlos M. Farinha, Paulo Matos, and Hugo M. Botelho

8. Quantification of a Non-Conventional Protein Secretion: The Low Molecular Weight FGF-2 Example

Tania Arcondйguy, Christian Touriol, and Eric Lacazette

9. Human Primary Keratinocytes as a Tool for the Analysis of Caspase-1-Dependent Unconventional Protein Secretion

Gerhard E. Strittmatter, Martha Garstkiewicz, Jennifer Sand, Serena Grossi, Hans-Dietmar Beer

10. A Reporter System to Study Unconventional Secretion of Proteins Avoiding N-glycosylation in Ustilago maydis

Janpeter Stock, Marius Terfrьchte, and Kerstin Schipper

11. Stress-inducible Protein 1 (STI1): Extracellular Vesicles Analysis And Quantification

Marcos Vinicios Salles Dias, Vilma Regina Martins, and Glaucia Noeli Maroso Hajj

12. Analysis of Yeast Extracellular Vesicles

Marcio L. Rodrigues, Debora L. Oliveira, Gabriele Vargas, Wendell Girard-Dias, Anderson J. Franzen, Susana Frasйs, Kildare Miranda, and Leonardo Nimrichter

13. Exploring the Leishmania Hydrophilic Acylated Surface Protein B (HASPB) Export Pathway by Live Cell Imaging Methods

Lorna MacLean, Helen Price, and Peter O'Toole

14. Characterization of the Unconventional Secretion of the Ebola Matrix Protein VP40

Olivier Reynard and Mathieu Mateo

15. Role and Characterization of synuclein-γ Unconventional Protein Secretion in Cancer Cells

Caiyun Liu, Like Qu, and Chengchao Shou

Part IV: Secretome Isolation from Plant and Animal Samples to Identify Leaderless Secretory Proteins (LSP)

16. Characterization of the Tumor Secretome from Tumor Interstitial Fluid (TIF)

Pavel Gromov and Irina Gromova

17. Vacuum Infiltration-Centrifugation Method for Apoplastic Protein Extraction in Grapevine

Bertrand Delaunois, Fabienne Baillieul, Christophe Clйment, Philippe Jeandet, and Sylvain Cordelier

18. Isolation of Exosome-Like Vesicles from Plants by Ultracentrifugation on Sucrose/Deuterium Oxide (D2O) Density Cushions

Christopher Stanly, Immacolata Fiume, Giovambattista Capasso, and Gabriella Pocsfalvi

Modeling Peptide-Protein Interactions : Methods and Protocols

Автор: Schueler-Furman, Ora;London, Nir
Название: Modeling Peptide-Protein Interactions : Methods and Protocols
ISBN: 1493967967 ISBN-13(EAN): 9781493967964
Издательство: Springer
Рейтинг:
Цена: 13974.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This volume covers an array of techniques available for studying peptide-protein docking and design.


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