Photoinduced Phenomena in Nucleic Acids II, Mario Barbatti; Antonio Carlos Borin; Susanne Ullr
Автор: Jurga Название: Modified Nucleic Acids in Biology and Medicine ISBN: 3319341731 ISBN-13(EAN): 9783319341736 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume is comprised of 18 chapters, covering various aspects of DNA modification and RNA modified bases. It also discusses in detail circular RNA, therapeutic oligonucleotides and their different properties. The chemical nature of DNA, RNA, protein and lipids makes these macromolecules easily modifiable, but they are also susceptible to damage from both endogenous and exogenous agents. Alkylation and oxidation show a potential to disrupt the cellular redox equilibrium and cause cellular damage leading to inflammation and even chronic disease. Furthermore, DNA damage can drive mutagenesis and the resulting DNA sequence changes can induce carcinogenesis and cancer progression. Modified nucleosides can occur as a result of oxidative DNA damage and RNA turnover, and are used as markers for various diseases. To function properly some RNA needs to be chemically modified post-transcriptionally. Dysregulation of the RNA-modification pattern or of the levels of the enzymes that catalyze these modifications alters RNA functionality and can result in complex phenotypes, likely due to defects in protein translation. While modifications are best characterized in noncoding ribonucleic acids like tRNA and rRNA, coding mRNAs have also been found to contain modified nucleosides. This book is a valuable resource, not only for graduate students but also researchers in the fields of molecular medicine and molecular biology.
Автор: Mario Barbatti; Antonio Carlos Borin; Susanne Ullr Название: Photoinduced Phenomena in Nucleic Acids II ISBN: 3319132717 ISBN-13(EAN): 9783319132716 Издательство: Springer Рейтинг: Цена: 36570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole.
Описание: The work presented in this thesis involves a number of sophisticated experiments highlighting novel applications of the Pixel Imaging Mass Spectrometry (PImMS) camera in the field of photoinduced molecular dynamics.
Автор: R.F. Khairutdinov; Jochen Mattay; H.D. Roth; P. Su Название: Photoinduced Electron Transfer IV ISBN: 3662149877 ISBN-13(EAN): 9783662149874 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: 1. K. Zamaraev, R. Khairutdinov: Photoinduced Electron Tunneling Reactions in Chemistry and Biology 2. P. Suppan: The Marcus Inverted Region 3. H.D. Roth: Structure and Reactivity of Organic Radical Cations
Автор: Jochen Mattay; M.A. Fox; D. Gust; S.V. Lymar; J. M Название: Photoinduced Electron Transfer III ISBN: 3662150174 ISBN-13(EAN): 9783662150177 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The work presented in this thesis involves a number of sophisticated experiments highlighting novel applications of the Pixel Imaging Mass Spectrometry (PImMS) camera in the field of photoinduced molecular dynamics.
Автор: Manoj Shukla; Jerzy Leszczynski Название: Radiation Induced Molecular Phenomena in Nucleic Acids ISBN: 9048177979 ISBN-13(EAN): 9789048177974 Издательство: Springer Рейтинг: Цена: 64148.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Comprehensive theoretical and experimental analysis of UV-radiation and low energy electron induced phenomena in nucleic acid bases (NABs) and base assemblies are presented in this book.
Автор: JORGEN KJEMS, Elena Ferapontova, Kurt V. Gothelf Название: Nucleic Acid Nanotechnology ISBN: 3642388140 ISBN-13(EAN): 9783642388149 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book surveys the intersection of nucleic acid research with nanotechnology, including advances in synthetic modifications, applications in bioengineering, nanoscale design, medicine, genetic analysis, chemistry, molecular biology and material science.
Автор: Peter B. Gahan Название: Circulating Nucleic Acids in Plasma and Serum ISBN: 9400790414 ISBN-13(EAN): 9789400790414 Издательство: Springer Рейтинг: Цена: 30606.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: DNA and RNA fractions have been isolated from the whole blood, serum, plasma, the surface of blood cells, urine, saliva and spinal fluid from both healthy individuals and clinical patients. Recent developments are presented concerning the isolation, quantification and analysis of these molecules and their use in the identification of specific nucleic acid fragments related to a variety of clinical disorders thereby permitting their early diagnosis and prognosis.
Автор: Volker A. Erdmann; Wojciech T. Markiewicz; Jan Bar Название: Chemical Biology of Nucleic Acids ISBN: 3662513242 ISBN-13(EAN): 9783662513248 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: new approaches to detect appropriately modified RNAs with EPR spectroscopy and the use of parallel and high-throughput techniques for the analysis of the structure and new functions of nucleic acids.
Автор: Val?rie Gabelica Название: Nucleic Acids in the Gas Phase ISBN: 3662511266 ISBN-13(EAN): 9783662511268 Издательство: Springer Рейтинг: Цена: 14365.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book gives physical chemists a broader view of potential biological applications of their techniques for the study of nucleic acids in the gas phase.
Автор: Fritz Eckstein; David M. J. Lilley Название: Nucleic Acids and Molecular Biology ISBN: 3642837115 ISBN-13(EAN): 9783642837111 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A wide range of topics are covered, including articles on nucleic acid structure, through their interactions with proteins to the control of gene expression. Gene transcription is also covered, from the points of view of DNA methylation, mammalian ribosomal and avian lysozyme genes, and the control of transcription in the proto-oncogene c-fos.
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